Dr Nicholas Francis
I am an academic general practitioner and my research interests are around improving the management of problems commonly seen in general practice.
My research has primarily focused around three main areas:
1) Infections, complications of infections, and antimicrobial use and resistance.
2) Skin conditions, including eczema, acne, skin infections and molluscum contagiosum.
3) Respiratory conditions, including respiratory infections, COPD and asthma.
I lead a module on common infections that forms part of the Clinical Epidemiology Intercalated BSc for Medical Students.
I also contribute to the undergraduate medical education curriculum by teaching medical epidemiolgy, examining ISCEs, and acting as a mentor.
Current Research Projects
PACE: General Practitioner (GP) use of a C-Reactive Protein (CRP) Point of Care Test (POCT) to help target antibiotic prescribing to patients with Acute Exacerbations of Chronic Obstructive Pulmonary Disease (AECOPD) who are most likely to benefit.
I am co-Chief Investigator of this NIHR-HTA funded trial of CRP point of care testing to guide the use of antibiotics for acute exacerbation of COPD. http://www.pace-study.co.uk/
OSTRICH: Oral Steroids for the Resolution of Otitis media with effusion in Children
I am co-Chief Investigator of this NIHR-HTA funded trial of oral steroids to improve hearing loss in children with persistent otitis media with effusion. http://www.ostrich-study.co.uk/
CEDAR: Children's Ear Pain Study
I am the Principal Investigator for Wales for this NIHR-HTA funded trial of analgesic ear drops to reduce the use of antibiotics in children with acute otitis media. http://www.bristol.ac.uk/primaryhealthcare/researchthemes/cedar/
PREPARE: Platform for European Preparedness Against (Re-)Emerging Epidemics
This is a large EU-funded project that aims to conduct large-scale clinical research studies on infectious diseases, and is prepared to rapidly respond to any severe infectious disease outbreak. I am involved in work package 1, which seeks to identify and implement solutions to any ethical, administrative, regulatory or legal bottlenecks to conducting research in an infectious disease pandemic. I am also on the trial management group for the ALIC4E trial (https://www.phc.ox.ac.uk/phctrials/trial-portfolio/alic4e) which forms work package 4. https://www.prepare-europe.eu/