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All Publications 2001-13 (K-R)

KNUPP C

Understanding the organisation and role of myosin binding protein C in normal striated muscle by comparison with MyBP-C knockout cardiac muscle.
Luther PK, Bennett PM, Knupp C, Craig R, Padrón R, Harris SP, Patel J, Moss RL.
J Mol Biol. 2008 Dec 5;384(1):60-72.

Zebrafish--topical, transparent, and tractable for ultrastructural studies.
Squire JM, Knupp C, Luther PK.
J Gen Physiol. 2008 May;131(5):439-43.

Rajkumar G, Al-Khayat HA, Eakins F, Knupp C, Squire JM.
The CCP13 FibreFix program suite: semi-automated analysis of diffraction patterns from non-crystalline materials
Journal of Applied Crystallography 40: 178-184 Part 1 2007 

Squire JM, Bekyarova T, Farman G, Gore D, Rajkumar G, Knupp C, Lucaveche C, Reedy MC, Reedy MK, Irving TC.
The myosin filament superlattice in the flight muscles of flies: A-band lattice optimisation for stretch-activation?
J Mol Biol. 2006 1; 361(5):823-38. 

Knupp C, Pinali C, Munro PM, Gruber HE, Sherratt MJ, Baldock C, Squire JM.
Structural correlation between collagen VI microfibrils and collagen VI banded aggregates.
J Struct Biol. 2006; 154(3):312-26. 

Squire JM, Al-Khayat HA, Knupp C, Luther PK.
Molecular architecture in muscle contractile assemblies,
Advances in Protein Chemistry 71: 17+ 2005

Squire JM, Knupp C.
X-ray diffraction studies of muscle and the crossbridge cycle
Advances in Protein Chemistry 71: 195+ 2005 

Squire JM, Knupp C, Roessle M.
X-ray diffraction studies of striated muscles
Advances in Experimental Medicine and Biology 565: 45-60 2005 

Knupp C, Squire JM.
Molecular packing in network-forming collagens
Advances in Protein Chemistry 70: 375+ 2005 

Squire JM, Knupp C.
MusLABEL: A program to model striated muscle A-band lattices, to explore crossbridge interaction geometries and to simulate muscle diffraction patterns,
Journal of Muscle Research and Cell Motility 25 (4-5): 423-438 2004 

Squire JM, Roessle M, Knupp C.
New X-ray diffraction observations on vertebrate muscle: Organisation of C-protein (MyBP-C) and troponin and evidence for unknown structures in the vertebrate A-band,
Journal of Molecular Biology 343 (5): 1345-1363 2004 

Knupp C, Squire JM.
HELIX: a helical diffraction simulation program
Journal of Applied Cystallography 37: 832-835 Part 5 2004 

Amin S, Chong NHV, Bailey TA, Zhang JJ, Knupp C, Cheetham ME, Greenwood J, Luthert PJ.
Modulation of Sub-RPE deposits in vitro: A potential model for age-related macular degeneration,
Investigative Ophthalmology & Visual Science 45 (5): 1281-1288 2004 

Squire JM, Al-Khayat HA, Harford JJ, Hudson L, Irving TC, Knupp C, Mok NS, Reedy MK.
Myosin filament structure and myosin crossbridge dynamics in fish and insect muscles,
Advances in Experimental Medicine and Biology 538: 251-266 2003 

Squire JM, Luther PK, Knupp C.
Structural evidence for the interaction of C-protein (MyBP-C) with actin and sequence identification of a possible actin-binding domain
Journal of Molecular Biology 331 (3): 713-724 2003 

Squire JM, Al-Khayat HA, Harford JJ, Hudson L, Irving T, Knupp C, Reedy MK.
Modelling muscle motor conformations using low-angle X-ray diffraction.
IEE Proc Nanobiotechnol. 2003; 150(3):103-110. 

Knupp C, Squire JM.
Molecular packing in network-forming collagens.
ScientificWorld Journal. 2003 23; 3:558-77. 

Knupp C, Amin SZ, Munro PM, Luthert PJ, Squire JM.
Collagen VI assemblies in age-related macular degeneration.
J Struct Biol. 2002; 139(3):181-9.

Knupp C, Luther PK, Squire JM.
Titin organisation and the 3D architecture of the vertebrate-striated muscle I-band.
J Mol Biol. 2002 27; 322(4):731-9. 

Knupp C, Amin SZ, Munro PMG.
Collagen VI assemblies in age-related macular degeneration,
Journal of Structural Biology 139 (3): 181-189 2002 

Knupp C, Luther PK, Squire JM.
Titin organisation and the 3D architecture of the vertebrate-striated muscle I-band,
Journal of Molecular Biology 322 (4): 731-739 27 2002 0

Knupp C, Chong NHV, Munro PMG, Luthert PJ, Squire JM.
Analysis of the collagen VI assemblies associated with Sorsby's fundus dystrophy,
Journal of Structural Biology 137 (1-2): 31-40 2002

Squire JM, Knupp C, Mok NS.
Using fast time-resolved X-ray diffraction to monitor the crossbridge cycle,
Biophysical Journal 80 (1): 334 Part 2 2001 

Knupp C, Squire JM.
A new twist in the collagen story - the type VI segmented supercoil, Embo
Journal 20 (3): 372-376 2001 

 

MARGRAIN T

New approach to evaluate retinal protection by intraocular lenses against age-related lipofuscin accumulation-mediated retinal phototoxicity.
Carson D, Margrain TH, Patel A.
J Cataract Refract Surg. 2008 Oct;34(10):1785-92.

Evaluating patient anxiety levels during contact lens fitting.
Court H, Greenland K, Margrain TH.
Optom Vis Sci. 2008 Jul;85(7):574-80.

Measuring low vision service outcomes: Rasch
Ryan B, Court H, Margrain TH. Optom Vis Sci. 2008 Feb;85(2):112-21.

Court H, Greenland K, Margrain TH.
Content development of the optometric patient anxiety scale,
Optometry & Vision Science 84 (8): 729-737 2007

Binns AM, Margrain TH.
Evaluating retinal function in age-related maculopathy with the ERG photo stress test.,
Investigative Ophthalmology & Visual Science 48 (6): 2806-2813 2007

Wiggins D, Woodhouse JM, Margrain TH, Harris CM, Erichsen JT.
Infantile nystagmus adapts to visual demand,
Investigative ophthalmology & visual science 48 (5): 2089-2094 2007

Binns A, Margrain TH.
Development of a technique for recording the focal rod ERG
Ophthalmic and Physiological Optics 26 (1): 71-79 2006 

Wiggins D, Erichsen J, Margrain T, Woodhouse M.
The consequences of eye position for nystagmus patients,
Spatial Vision 18 (4): 506-506 2005 

Binns A, Margrain TH.
Evaluation of retinal function using the dynamic focal cone ERG,
Ophthalmic and Physiological Optics 25 (6): 492-500 2005

Qin XJ, Margrain TH, To CH, Bromham N, Guggenheim JA.
Anisometropia is independently associated with both spherical and cylindrical ametropia.
Invest Ophthalmol Vis Sci. 2005; 46(11):4024-31. 

Margrain TH, Ryan B, Wild JM.
A revolution in Welsh low vision service provision.
British Journal of Ophthalmology. 2005; 89(8):933-4. 

Margrain TH, Boulton M, Marshall J, Sliney DH.
Do blue light filters confer protection against age-related macular degeneration?
Prog Retin Eye Res. 2004; 23(5):523-31. 

Margrain TH, Greenland K, Anderson J.
Evaluating anxiety in patients attending optometric practice.
Ophthalmic Physiol Opt. 2003; 23(4):287-93. 

Freeman TC, Naji JJ, Margrain TH.
Head-centred motion perception in the ageing visual system.
Spat Vis. 2002; 15(2):117-27. 

Margrain TH, Thomson D.
Sources of variability in the clinical photostress test.
Ophthalmic Physiol Opt. 2002; 22(1):61-7. 

 

MEEK K

Light transmission in the human cornea as a function of position across the ocular surface: theoretical and experimental aspects.
Doutch J, Quantock AJ, Smith VA, Meek KM.
Biophys J. 2008 Dec;95(11):5092-9.

Immunochemical localization of keratan sulfate proteoglycans in cornea, sclera, and limbus using a keratanase-generated neoepitope monoclonal antibody. Akhtar S, Kerr BC, Hayes AJ, Hughes CE, Meek KM, Caterson B.
Invest Ophthalmol Vis Sci. 2008 Jun;49(6):2424-31.

Ultrastructural analysis of collagen fibrils and proteoglycans in keratoconus.
Akhtar S, Bron AJ, Salvi SM, Hawksworth NR, Tuft SJ, Meek KM.
Acta Ophthalmol. 2008 Nov;86(7):764-72.

Effect of complete epithelial debridement before riboflavin-ultraviolet-A corneal collagen crosslinking therapy.
Hayes S, O'Brart DP, Lamdin LS, Doutch J, Samaras K, Marshall J, Meek KM.
J Cataract Refract Surg. 2008 Apr;34(4):657-61.

Boote C, Hayes S, Jones S, Quantock AJ, Hocking PM, Inglehearn CF, Ali M, Meek KM. 
Collagen organization in the chicken cornea and structural alterations in the retinopathy, globe enlarged (rge) phenotype-An X-ray diffraction study.
J Struct Biol. 2007 7; 

Doutch J, Tucker C, Quantock AJ, Ade PAR and Meek KM.
Propagation of infrared wavelengths through the corneal stroma with reference to hydration changes
Proc. of SPIE in Press

Doutch J, Quantock AJ and Meek, KM.
Changes in visible light transmission across the corneal surface.
Proc.of SPIE in Press

Hayes S, Boote C, Tuft SJ, Quantock AJ, Meek KM.
A study of corneal thickness, shape and collagen organisation in keratoconus using videokeratography and X-ray scattering techniques.
Exp Eye Res. 2006 15; 

Hayashida Y, Akama TO, Beecher N, Lewis P, Young RD, Meek KM, Kerr B, Hughes CE, Caterson B, Tanigami A, Nakayama J, Fukada MN, Tano Y, Nishida K, Quantock AJ.
Matrix morphogenesis in cornea is mediated by the modification of keratan sulfate by GlcNAc 6-O-sulfotransferase.
Proc Natl Acad Sci U S A. 2006 5;103(36):13333-8. 

Boote C, Hayes S, Abahussin M, Meek KM.
Mapping collagen organization in the human cornea: left and right eyes are structurally distinct. Invest
Ophthalmol Vis Sci. 2006 ;47(3):901-8. 

Beecher N, Chakravarti S, Joyce S, Meek KM, Quantock AJ.
Neonatal development of the corneal stroma in wild-type and lumican-null mice.
Invest Ophthalmol Vis Sci. 2006 ;47(1):146-50. 

Beecher N, Carlson C, Allen BR, Kipchumba R, Conrad GW, Meek KM, Quantock AJ.
An x-ray diffraction study of corneal structure in mimecan-deficient mice.
Invest Ophthalmol Vis Sci. 2005 ;46(11):4046-9. 

Young RD, Tudor D, Hayes AJ, Kerr B, Hayashida Y, Nishida K, Meek KM, Caterson B, Quantock AJ.
Atypical composition and ultrastructure of proteoglycans in the mouse corneal stroma.
Investigative Ophthalmology & Visual Science. 2005 ;46(6):1973-8. 

Meek KM, Tuft SJ, Huang Y, Gill PS, Hayes S, Newton RH, Bron AJ.
Changes in collagen orientation and distribution in keratoconus corneas.
Investigative Ophthalmology & Visual Science. 2005 ;46(6):1948-56. 

Boote C, Dennis S, Huang Y, Quantock AJ, Meek KM.
Lammellar orientation in human cornea in relation to mechanical properties.
Journal of Structual Biology. 2005 ; 149(1): 1-6.

Akhtar S, Bron AJ, Qin X, Creer RC, Guggenheim JA, Meek KM. 
Gelatinous drop-like corneal dystrophy in a child with developmental delay: clinicopathological features and exclusion of the M1S1 gene.
Eye. 2005; 19(2):198-204.

Akhtar S, Bron AJ, Meek KM, Voon LW.
Clinical and ultrastructural findings in mare's tail lines of the corneal epithelium.
British Journal of Ophthalmology. 2004; 88(7):864-7.

Sturrock, EJ, Boote, C, Attenburrow, GE and Meek, KM
The effects of the biaxial stretching of leather on fibre orientation and tensile modulus.
Journal of Materials Science.2004 39 2481-2486

Bazou, D., Coakley, W.T., Meek, K.M., Yang, M. and Pham, D.T.
Characterisation of the morphology of 2-D particle aggregates in different electrolyte concentrations in an ultrasound trap.
Colloids and Surfaces: Physicochemical and Engineering Aspects 2004 243, 97-104.

Meek KM, Boote C.
The organization of collagen in the corneal stroma.
Exp Eye Res. 2004; 78(3):503-12. 

Boote C, Dennis S, Meek K.
Spatial mapping of collagen fibril organisation in primate cornea-an X-ray diffraction investigation.
Journal of Structual Biology. 2004 ;146(3):359-67. 

Connon CJ, Meek KM.
The structure and swelling of corneal scar tissue in penetrating full-thickness wounds.
Cornea. 2004 ;23(2):165-71. 

Connon CJ, Meek KM, Kinoshita S, Quantock AJ.
Spatial and temporal alterations in the collagen fibrillar array during the onset of transparency in the avian cornea.
Experimental Eye Research. 2004; 78(5):909-15 

Aghamohammadzadeh H, Newton RH, Meek KM.
X-ray scattering used to map the preferred collagen orientation in the human cornea and limbus.
Structure. 2004; 12(2):249-56. 

Meek KM, Quantock AJ, Boote C, Liu CY, Kao WW.
An X-ray scattering investigation of corneal structure in keratocan-deficient mice.
Matrix Biol. 2003; 22(6):467-75. 

Meek KM, Leonard DW, Connon CJ, Dennis S, Khan S.
Transparency, swelling and scarring in the corneal stroma.
Eye. 2003; 17(8):927-36. 

Meek KM, Dennis S, Khan S. Changes in the refractive index of the stroma and its extrafibrillar matrix when the cornea swells.
Biophys J. 2003; 85(4):2205-12. 

Boote C, Dennis S, Newton RH, Puri H, Meek KM.
Collagen fibrils appear more closely packed in the prepupillary cornea: optical and biomechanical implications.
Investigative Ophthalmology & Visual Science. 2003 ;44(7):2941-8. 

Connon CJ, Siegler V, Meek KM, Hodson SA, Caterson B, Kinoshita S, Quantock AJ.
Proteoglycan alterations and collagen reorganisation in the secondary avian cornea during development.
Ophthalmic Research. 2003; 35(4):177-84.

Connon CJ, Marshall J, Patmore AL, Brahma A, Meek KM.
Persistent haze and disorganization of anterior stromal collagen appear unrelated following phototherapeutic keratectomy.
J Refract Surg. 2003; 19(3):323-32. 

Quantock AJ, Dennis S, Adachi W, Kinoshita S, Boote C, Meek KM, Matsushima Y, Tachibana M.
Annulus of collagen fibrils in mouse cornea and structural matrix alterations in a murine-specific keratopathy.
Investigative Ophthalmology & Visual Science. 2003; 44(5):1906-11. 

Connon CJ, Meek KM.
Organization of corneal collagen fibrils during the healing of trephined wounds in rabbits.
Wound Repair Regen. 2003; 11(1):71-8. 

Quantock AJ, Boote C, Siegler V, Meek KM.
Collagen organization in the secondary chick cornea during development.
Investigative Ophthalmology & VisualScience 2003 ;44(1):130-6. 

Boote C, Siegler V, Meek KM, Quantock AJ
A wide-angle x-ray diffraction study of the developing embryonic chicken cornea.
Fibre Diffraction Review 2003 11, 123-129. 

Kostyuk O, Nalovina O, Mubard TM, Regini JW, Meek KM, Quantock AJ, Elliott GF, Hodson SA.
Transparency of the bovine corneal stroma at physiological hydration and its dependence on concentration of the ambient anion.
J Physiol. 2002 1;543(Pt 2):633-42.

Akhtar S, Tullo A, Caterson B, Davies JR, Bennett K, Meek KM.
Clinical and morphological features including expression of betaig-h3 and keratan sulphate proteoglycans in Maroteaux-Lamy syndrome type B and in normal cornea.
British Journal of Ophthalmology. 2002; 86(2):147-51. PMID: 11815337

Meek, KM (2002)
The Cornea. In Signals and Perception (D. Roberts, ed.).  pp 103-114.
Palgrave Macmillan, New York Also a book contribution:

Huang Y, Meek KM, Ho MW, Paterson CA.
Anaylsis of birefringence during wound healing and remodeling following alkali burns in rabbit cornea.
Exp Eye Res. 2001; 73(4):521-32. PMID: 11825023

Quantock AJ, Meek KM, Chakravarti S.
An x-ray diffraction investigation of corneal structure in lumican-deficient mice.
Investigative Ophthalmology & Visual Science 2001 ;42(8):1750-6. 

Akhtar S, Bron AJ, Meek KM, Bennett K.
Congenital hereditary endothelial dystrophy and band keratopathy in an infant with corpus callosum agenesis.
Cornea. 2001; 20(5):547-52. 

Akhtar S, Bron AJ, Hawksworth NR, Bonshek RE, Meek KM.
Ultrastructural morphology and expression of proteoglycans, betaig-h3, tenascin-C, fibrillin-1, and fibronectin in bullous keratopathy.
British Journal of Ophthalmology. 2001; 85(6):720-31. 

Meek KM, Quantock AJ.
The use of X-ray scattering techniques to determine corneal ultrastructure.
Prog Retin Eye Res. 2001; 20(1):95-137. 

Hadley J, Malik N, Meek K.
Collagen as a model system to investigate the use of aspirin as an inhibitor of protein glycation and crosslinking.
Micron. 2001; 32(3):307-15. 

Meek KM, Fullwood NJ.
Corneal and scleral collagens--a microscopist's perspective.
Micron. 2001; 32(3):261-72. 

Sturrock, EJ, Attenburrow, GE, Boote, C and Meek, KM
The effect on bending stiffness of drying leather under strain.
J Leather Tech. and Chem 2001. 86 6-10

 

MORGAN JE

Adenovirus-based targeting in myoblasts is hampered by nonhomologous vector integration.
Isman O, Roberts ML, Morgan JE, Graham IR, Goldring K, Lawrence-Watt DJ, Lu QL, Dunckley MG, Porter AC, Partridge TA, Dickson G. Hum Gene
Ther. 2008 Oct;19(10):1000-8.

Transscleral cyclodiode laser photocoagulation in the treatment of aqueous misdirection syndrome.
Stumpf TH, Austin M, Bloom PA, McNaught A, Morgan JE.
Ophthalmology. 2008 Nov;115(11):2058-61.

Quantification of retinal transneuronal degeneration in human glaucoma: a novel multiphoton-DAPI approach.
Lei Y, Garrahan N, Hermann B, Becker DL, Hernandez MR, Boulton ME, Morgan JE.
Invest Ophthalmol Vis Sci. 2008 May;49(5):1940-5.

Three-dimensional optical coherence tomography at 1050 nm versus 800 nm in retinal pathologies: enhanced performance and choroidal penetration in cataract patients.
Povazay B, Hermann B, Unterhuber A, Hofer B, Sattmann H, Zeiler F, Morgan JE, Falkner-Radler C, Glittenberg C, Blinder S, Drexler WJ Biomed
Opt. 2007 ;12(4):041211. 

Povazay B, Hofer B, Hermann B, Unterhuber A, Morgan JE, Glittenberg C, Binder S, Drexler W.
Minimum distance mapping using three-dimensional optical coherence tomography for glaucoma diagnosis.
J Biomed Opt. 2007 12(4):041204. 

Prashar A, Guggenheim JA, Erichsen JT, Hocking PM, Morgan JE.
Measurement of intraocular pressure (IOP) in chickens using a rebound tonometer: Quantitative evaluation of variance due to position inaccuracies.
Experimental Eye Research. 2007; 85(4):563-71.

Albon J, Farrant S, Akhtar S, Young R, Boulton ME, Smith G, Taylor M Guggenheim J, Morgan JE.
Connective tissue structure of the tree shrew optic nerve and associated ageing changes
Investigative Ophthalmology & Visual Science 48 (5): 2134-2144 2007 

Dhingra N, Morgan JE.
Pseudophakic cystoid macular oedema: 30 months after latanoprost challenge,
EYE 21 (2): 269-271 2007 

Bennett SL, Hewitt AW, Poulsen JL, Kearns LS, Morgan JE, Craig JE, Mackey DA.
Screening for glaucomatous disc changes prior to diagnosis of glaucoma in myocilin pedigrees,
Archives of Ophthalmology 125 (1): 112-116 2007 

North RV, Jones AL, Hunter E, Morgan JE, Wild JM.
Evaluation of the high specificity Screening Program (C-20-1) of the Frequency Doubling Technology (FDT) perimeter in clinical practice
Eye 20 (6): 681-687 2006 

Hewitt AW, Traill A, Cooper RL, Morgan JE, Mackey DA.
Tools for cup: disc ratio measurement
Clinical and Experimental Ophthalmology 34 (3): 288-289 2006 

Morgan JE, Datta AV, Erichsen JT,Erichsen JT, Albon J, Boulton ME.
Retinal ganglion cell remodelling in experimental glaucoma,
Advances in Experimental Medicine and Biology 572: 397-402 2006 

Hadjikoutis S, Morgan JE, Wild JM.
Ocular complications of neurological therapy,
European Journal of Neurology 12 (7): 499-507 2005 

Morgan JE, Sheen NJL, North RV, Choong Y, Ansari E.
Digital imaging of the optic nerve head: monoscopic and stereoscopic analysis,
British Journal of Ophthalmology 89 (7): 879-884 2005 

Morgan JE, Sheen NJL, North RV.
Discrimination of glaucomatous optic neuropathy by digital stereoscopic analysis,
Ophthalmology 112 (5): 855-862 2005 

Frenkel S, Morgan JE,
Blumenthal EZ.Histological measurement of retinal nerve fibre layer thickness,
Eye 19 (5): 491-498 2005 

Morgan JE.
Circulation and axonal transport in the optic nerve
Eye 18 (11): 1089-1095 2004 

Sheen NJL, Morgan JE, Poulsen JL.
Digital stereoscopic analysis of the optic disc - Evaluation of a teaching program,
Ophthalmology 111 (10): 1873-1879 2004 

Aldebasi YH, Drasdo N, Morgan JE.
S-cone, L+M-cone, and pattern, electroretinograms in ocular hypertension and glaucoma
Vision Research 44 (24): 2749-2756 2004 

Bizheva K, Unterhuber A, Hermann B, Povazay B, Sattmann H, Drexler W, Stingl A, Le T, Mei M, Holzwarth R, Reitsamer HA, Morgan JE.
Imaging ex vivo and in vitro brain morphology in animal models with ultrahigh resolution optical coherence tomography
Journal of Biomedical Optics 9 (4): 719-724 2004 

Anger EM, Unterhuber A, Hermann B, Sattmann H, Schubert C, Morgan JE, Cowey A, Ahnelt PK, Drexler W.
Ultrahigh resolution optical coherence tomography of the monkey fovea. Identification of retinal sublayers by correlation with semithin histology sections,
Experimental Eye Research 78 (6): 1117-1125 2004 

Unterhuber A, Povazay B, Bizheva K, Hermann B, Sattmann H, Stingl A, Le T, Seefeld M, Menzel R, Preusser M, Budka H, Schubert C, Reitsamer H, Ahnelt PK, Morgan JE, Cowey A, Drexler W.
Advances in broad bandwidth light sources for ultrahigh resolution optical coherence tomography,
Physics in Medicine and Biology 49 (7): 1235-1246 2004 

Sinha S, Pathak-Ray V, Ahluwalia H, Ahluwalia H, Morgan JE.
Viagra or what?
Eye 18 (4): 446-448 2004 

Goyal R, North RV, Morgan JE.
Comparison of laser interferometry and ultrasound A-scan in the measurement of axial length,
Acta Ophthalmologica Scandinavica 81 (4): 331-335 2003 

Unterhuber A, Povazay B, Hermann B, Sattmann H, Drexler W, Yakovlev V, Tempea G, Schubert C, Anger EM, Ahnelt PK, Stur M, Morgan JE, Cowey A, Jung G, Le T, Stingl A.
Compact, low-cost Ti : Al2O3 laser for in vivo ultrahigh-resolution optical coherence tomography,
Optics Letters 28 (11): 905-907 2003 

Rakebrandt F, North RV, Erichsen JT, Drasdo N, Fowler C, Cowey A, Morgan JE.
The construction of a model eye for investigation of laser-tissue interactions in scanning laser ophthalmoscopy
Optometry and Vision Science 80 (3): 252-258 2003 

Choong YF, Rakebrandt F, North RV, Morgan JE.
Acutance, an objective measure of retinal nerve fibre image clarity,
British Journal of Ophthalmology 87 (3): 322-326 2003 

Aldebasi YH, Drasdo N, Morgan JE.
Cortical OFF-potentials from the S-cone pathway reveal neural damage in early glaucoma,
Vision Research 43 (2): 221-226 2003 

Ansari EA, Morgan JE, Snowden RJ.
Psychophysical characterisation of early functional loss in glaucoma and ocular hypertension,
British Journal of Ophthalmology 86 (10): 1131-1135 2002 

Drasdo N, Aldebasi YH, Mortlock KE, Chiti Z, Morgan JE, North RV, Wild JM.
Ocular optics, electroretinography and primary open angle glaucoma,
Ophthalmic and Physiological Optics 22 (5): 455-462  2002 

Morgan JE, Diamond JP, Cook SD.
Remodelling the filtration bleb
British Journal of Ophthalmology 86 (8): 872-875 2002 

Morgan JE.
Retinal ganglion cell shrinkage in glaucoma
Journal of Glaucoma 11 (4): 365-370 2002 

Ansari EA, Morgan JE, Snowden RJ.
Glaucoma: squaring the psychophysics and neurobiology,
British Journal of Ophthalmology 86 (7): 823-826 2002 

Jones AL, Sheen NJL, North RV, Morgan JE.
The Humphrey optical coherence tomography scanner: quantitative analysis and reproducibility study of the normal human retinal nerve fibre layer,
British Journal of Ophthalmology 85 (6): 673-677 2001 

Aldebasi YH, Drasdo N, North RV, Morgan JE.
The pattern electroretinogram (PERG) with contralateral corneal reference,
Ophthalmic and Physiological Optics 21 (3): 243-246  2001 

 Sheen NJL, Aldridge C, Drasdo N, North RV, Morgan JE.
The effects of astigmatism and working distance on optic nerve head images using a Heidelberg retina tomograph scanning laser ophthalmoscope,
American Journal of Ophthalmology 131 (6): 716-721 2001 

Drasdo N, Aldebasi YH, Chiti Z, Morgan JE.
The S-cone PhNR and pattern ERG in primary open angle glaucoma,
Investigative Ophthalmology & Visual Science 42 (6): 1266-1272 2001

Escardo JA, Feyi-Waboso A, Lane CM, Morgan JE.
Orbital cellulitis caused by Fusobacterium necrophorum,
American Journal of Ophthalmology 131 (2): 280-281 2001 

 

NORTH R

North RV, Jones AL, Drasdo N, Wild JM, Morgan JE
Electrophysiological Evidence of Early Functional Damage in Glaucoma and Ocular Hypertension.
Invest. Ophthalmol. Vis. Sci. 2010 51: 1216-1222. (2010)

Gutstein W, Sinclair SH,  North RV,  Bekiroglu N.
Screening athletes with Down syndrome for ocular disease.
Optometry, 81:94-99 (2010)

Evans K, North RV, Purslow C, 
Tear Ferning in Contact Lens Wearers.
Ophthalmic & Physiological Optics. 29(2):199-204. (2009)

Ganglion cell loss and dysfunction: relationship to perimetric sensitivity.
Drasdo N, Mortlock KE, North RV.
Optom Vis Sci. 2008 Nov;85(11):1036-42.

North RV, Jones AL, Hunter E, Morgan JE, Wild JM.
Evaluation of the high specificity Screening Program (C-20-1) of the Frequency Doubling Technology (FDT) perimeter in clinical practice.
Eye. 2006; 20(6):681-7. 

Mortlock KE, Chiti Z, Drasdo N, North RV.
Silent substitution S-cone electroretinogram in subjects with diabetes mellitus,
Ophthalmic and Physiological Optics 25 (5): 392-399 2005 

Morgan JE, Sheen NJL, North RV, Choong Y, Ansari E.
Digital imaging of the optic nerve head: monoscopic and stereoscopic analysis,
British Journal of Ophthalmology 89 (7): 879-884 2005 

Morgan JE, Sheen NJL, North RV.
Discrimination of glaucomatous optic neuropathy by digital stereoscopic analysis
Ophthalmology 112 (5): 855-862 2005 

Arlotte DV, Perrott RL, Drasdo N, Owens DR, North RV.
The effect of post prandial glucose changes on oscillatory potentials in subjects with type 2 diabetes mellitus
Documenta Ophthalmologica 109 (1): 35-42 2004 

Sheen NJL, Morgan JE, Poulsen JL, North RV.
Digital stereoscopic analysis of the optic disc - Evaluation of a teaching program,
Ophthalmology 111 (10): 1873-1879 2004 

Aldebasi YH, Drasdo N, Morgan JE, North RV.
S-cone, L+M-cone, and pattern, electroretinograms in ocular hypertension and glaucoma,
Vision Research 44 (24): 2749-2756 2004 

Chiti Z, North RV, Mortlock KE.
The S-cone electroretinogram: a comparison of techniques, normative data and age-related variation,
Ophthalmic and Physiological Optics 23 (4): 370-376 2003 

Goyal R, North RV, Morgan JE.
Comparison of laser interferometry and ultrasound A-scan in the measurement of axial length,
Acta Ophthalmologica Scandinavica 81 (4): 331-335 2003 

Rakebrandt F, North RV, Erichsen JT.
The construction of a model eye for investigation of laser-tissue interactions in scanning laser ophthalmoscopy,
Optometry and Vision Science 80 (3): 252-258 2003 

Choong YF, Rakebrandt F, North RV.
Acutance, an objective measure of retinal nerve fibre image clarity,
British Journal of Ophthalmology 87 (3): 322-326 2003 

Aldebasi YH, Drasdo N, Morgan JE, North RV.
Cortical OFF-potentials from the S-cone pathway reveal neural damage in early glaucoma
Vision Research 43 (2): 221-226 2003 

Drasdo N, Aldebasi YH, Mortlock KE, Chiti Z, Morgan JE, North RV, Wild JM.
Ocular optics, electroretinography and primary open angle glaucoma,
Ophthalmic and Physiological Optics 22 (5): 455-462  2002 

Drasdo N, Chiti Z, Owens DR, North RV.
Effect of darkness on inner retinal hypoxia in diabetes,
Lancet 359 (9325): 2251-2253 2002 

Drasdo N, Aldebasi YH, Chiti Z, Mortlock KE, Morgan JE, North RV.
The s-cone PHNR and pattern ERG in primary open angle glaucoma.
Investigative Ophthalmology & Visual Science 2001; 42(6):1266-72. 

Perrott RL, North RV, Drasdo N.
The influence of plasma glucose upon pulsatile ocular blood flow in subjects with Type II diabetes mellitus,
Diabetologia 44 (6): 700-705 2001 

Jones AL, Sheen NJL, North RV.
The Humphrey optical coherence tomography scanner: quantitative analysis and reproducibility study of the normal human retinal nerve fibre layer,
British Journal of Ophthalmology 85 (6): 673-677 2001 

Aldebasi YH, Drasdo N, North RV.
The pattern electroretinogram (PERG) with contralateral corneal reference,
Ophthalmic and Physiological Optics 21 (3): 243-246  2001 

Sheen NJL, Aldridge C, Drasdo N, North RV, Morgan JE.
The effects of astigmatism and working distance on optic nerve head images using a Heidelberg retina tomograph scanning laser ophthalmoscope,
American Journal of Ophthalmology 131 (6): 716-721 2001 

Drasdo N, Aldebasi YH, Chiti Z, Mortlock KE, Morgan JE, North RV.
The S-cone PhNR and pattern ERG in primary open angle glaucoma,
Investigative Ophthalmology & Visual Science 42 (6): 1266-1272 2001


QUANTOCK A

Actin and type I Collagen Propeptide Distribution in the Developing Chick Cornea.
Gealy CC, Hayes AJ, Buckwell RE, Young RD, Caterson B, Quantock AJ, Ralphs JR.
Invest Ophthalmol Vis Sci. 2008 Dec 13. [Epub ahead of print] PMID: 19074811

Genomic Aberrations and Cellular Heterogeneity in SV40-Immortalized Human Corneal Epithelial Cells.
Yamasaki K, Kawasaki S, Young RD, Fukuoka H, Tanioka H, Nakatsukasa M, Quantock AJ, Kinoshita S.
Invest Ophthalmol Vis Sci. 2008 Sep 29. [Epub ahead of print] PMID: 18824731

Sulfation patterns of keratan sulfate in different macular corneal dystrophy immunophenotypes using three different probes.
Saito T, Nishida K, Nakayama J, Akama TO, Fukuda MN, Watanabe K, Quantock AJ, Maeda N, Watanabe H, Tano Y.
Br J Ophthalmol. 2008 Oct;92(10):1434-6.

Light transmission in the human cornea as a function of position across the ocular surface: theoretical and experimental aspects.
Doutch J, Quantock AJ, Smith VA, Meek KM.
Biophys J. 2008 Dec;95(11):5092-9.

Development of the corneal stroma, and the collagen-proteoglycan associations that help define its structure and function. Quantock AJ, Young RD. Dev Dyn. 2008 Oct;237(10):2607-21. Review.

Collagen organization in the chicken cornea and structural alterations in the retinopathy, globe enlarged (rge) phenotype--an X-ray diffraction study.
Boote C, Hayes S, Jones S, Quantock AJ, Hocking PM, Inglehearn CF, Ali M, Meek KM. J Struct Biol. 2008 Jan;161(1):1-8.

Boote C, Hayes S, Jones S, Quantock AJ, Hocking PM, Inglehearn CF, Ali M, Meek KM.
Collagen organization in the chicken cornea and structural alterations in the retinopathy, globe enlarged (rge) phenotype-An X-ray diffraction study.
J Struct Biol. 2007 

Gealy EC, Kerr BC, Young RD, Tudor D, Hayes AJ, Hughes CE, Caterson B, Quantock AJ, Ralphs JR.
Differential expression of the keratan sulphate proteoglycan, keratocan, during chick corneal embryogenesis. Histochem
Cell Biol. 2007 

Young RD, Gealy EC, Liles M, Caterson B, Ralphs JR, Quantock AJ.
Keratan sulfate glycosaminoglycan and the association with collagen fibrils in rudimentary lamellae in the developing avian cornea,
Investigative Ophthalmology & Visual Science 48 (7): 3083-3088 2007

Regini JW, Grossmann JG, Timmins P, Harding JJ, Quantock AJ, Hodson SA, Elliott GF.
X-ray- and neutron-scattering studies of alpha-crystallin and evidence that the target protein sits in the fenestrations of the alpha-crystallin shell,
Investigative Ophthalmology & Visual Science 48 (6): 2695-2700, 2007 

Hayes S, Boote C, Tuft SJ, Quantock AJ, Meek KM.
A study of corneal thickness, shape and collagen organisation in keratoconus using videokeratography and X-ray scattering techniques
Experimental Eye Research 84 (3): 423-434 2007 

Young RD, Akama TO, Liskova P, Ebenezer ND, Allan B, Kerr B, Caterson B, Fukuda MN, Quantock AJ.
Differential immunogold localisation of sulphated and unsulphated keratan sulphate proteoglycans in normal and macular dystrophy cornea using sulphation motif-specific antibodies, Histochemistry and Cell Biology 127 (1): 115-120 2007

Beecher N, Chakravarti S, Joyce S, Meek KM, Quantock AJ.
Neonatal development of the corneal stroma in wild-type and lumican-null mice.
Investigative Ophthalmology & Visual Science. 2006 47:146-150. 

Connon CJ, Kawasaki S, Liles M, Koizumi N, Yamasaki K, Nakamura T, Quantock AJ, Kinoshita S.
Gene expression and immunolocalisation of a calcium-activated chloride channel during the stratification of cultivated and developing corneal epithelium.
Cell Tissue Research. 2006; 323:177-182.

Assiri AA, Yousuf, BI, Woodhouse JM, Quantock AJ, Murphy PJ.
Ultrasound biometry in the diagnosis of amblyopia in keratoconus.
Contact Lens and the Anterior Eye 2006; 29:75-79. 

Connon CJ, Nakamura T, Quantock AJ, Kinoshita S.
The persistence of transplanted amniotic membrane in corneal stroma.
Am J Ophthalmol 2006; 141:190-192. 

Young RD, Quantock AJ, Sotozono C, Koizumi N, Kinoshita S.
Sulphation patterns of keratan sulphate proteoglycan in sclerocornea resemble cornea rather than sclera
British Journal of Ophthalmology. 2006; 90:391-393. 

Hayashida Y, Akama TO, Beecher N, Lewis P, Young RD, Meek KM, Kerr B, Hughes CE, Caterson B, Tanigami A, Nakayama J, Fukada MN, Tano Y, Nishida K, Quantock AJ.
Matrix morphogenesis in cornea is mediated by the modification of keratan sulfate by GlcNAc 6-O sulfotransferase.
Proc Natl Acad Sci U.S.A. 2006; 103:13333-13338.

Young RD, Akama TO, Liskova P, Ebenezer ND, Allan B, Kerr B, Caterson B, Fukuda MN, Quantock AJ.
Differential immunogold localization of sulphated and unsulphated keratan sulphate proteoglycans in normal and macular dystrophy cornea using sulphation motif-specific antibodies.
Histochem and Cell Biol 2006;in press.

Hayes S, Boote C, Tuft SJ, Quantock AJ, Meek KM.
A study of corneal thickness, shape and collagen organisation in keratoconus using videokeratography and x-ray scattering techniques.
Experimental Eye Research. 2006; in press. 

Boote C, Dennis S, Huang Y, Quantock AJ, Meek KM.
Lamellar orientation in human cornea in relation to mechanical properties.
J Struct Biol 2005; 149:1-6. 

Connon CJ, Kawasaki S, Yamasaki K, Quantock AJ, Kinoshita S.
The quantification of hCLCA2 and colocalisation with integrin 4 in stratified human epithelia.
Acta Histochemica 2005; 106:421-425. 

Young RD, Tudor D, Hayes AJ, Kerr B, Hayashida Y, Nishida K, Meek KM, Caterson B, Quantock AJ.
Atypical composition and ultrastructure of proteoglycans in the mouse corneal stroma.
Investigative Ophthalmology & Visual Science. 2005; 46:1973-1978. 

Quantock AJ, Sano Y, Young RD, Kinoshita S. 
Stromal architecture and immune tolerance in additive corneal xenografts in rodents.
Acta Ophthalmologica 2005; 83;462-466. 

Assiri AA, Yousuf, BI, Quantock AJ, Murphy PJ.
Incidence and severity of keratoconus in Asir Province, Saudi Arabia.
British Journal of Ophthalmology 2005;11:1403-1406. 

Beecher N, Carlson C, Allen BR, Kipchumba R, Conrad GW, Meek KM, Quantock AJ.
An x-ray diffraction study of corneal structure in mimecan-deficient mice.
Invest Ophthalmol Vis Sci 2005; 46:4046-4050. 

Quantock AJ, Nishida K.
Restoring corneal function with bioengineered cell layers.
Optometry Today 2004, April 3, 38-40. 

Connon CJ, Yamasaki K, Kawasaki S, Quantock AJ, Koizumi N, Kinoshita S.
Calcium activated chloride channel-2 in human epithelia.
J Histochem Cytochem 2004; 52:415-418.

Connon CJ, Meek KM, Kinoshita S, Quantock AJ.
Spatial and temporal alterations in the collagen fibrillar array during the onset of transparency in the avian cornea.
Experimental Eye Research. 2004; 78:909-915.

Quantock AJ, Boote C, Siegler V, Meek KM.
Collagen organization in the secondary chick cornea during development.
Investigative Ophthalmology & Visual Science. 2003; 44:130-136.

Connon CJ, Siegler V, Meek KM, Hodson SA, Caterson B, Kinoshita S, Quantock AJ.
Proteoglycan alterations and collagen reorganization in the secondary avian cornea during development.
Ophthalmic Research. 2003; 35:1-8. 

Quantock AJ, Padroni S, Connon CJ, Milne G, Schanzlin DJ.
Proteoglycan alterations in the rabbit corneal stroma after a lamellar incision.
J Cat Ref Surg 2003;29:821-824. 

Boote C, Siegler V, Meek KM, Quantock AJ.
A wide-angle x-ray diffraction study of the developing embryonic chicken cornea.
Fibre Diffraction Review 2003; 11:123-129. 

Quantock AJ, Dennis S, Adachi W, Kinoshita S, Boote C, Meek KM, Matsushima Y, Tachibana M.
Annulus of collagen fibrils in mouse cornea and structural matrix alterations in a murine-specific keratopathy.
Investigative Ophthalmology & Visual Science 2003; 44:1906-1911.

Meek KM, Quantock AJ, Boote C, Liu CY, Kao WW-Y.
An x-ray scattering investigation of corneal structure in keratocan-deficient mice.
Matrix Biology 2003; 22:467-475. 

Siegler V, Quantock AJ.
Two-stage compaction of the secondary avian cornea during development.
Experimental Eye Research. 2002; 74:427-431.

Kostyuk O, Nalovina O, Mubard TM, Regini JW, Meek KM, Quantock AJ, Elliott GF, Hodson SA.
Transparency of the bovine corneal stroma at physiological hydration and its dependence on concentration of the ambient anion.
J Physiol 2002; 543:633-642. 

Kinoshita S, Nakamura T, Kawasaki S, Koizumi N, Ueno M, Ishino Y, Ban Y, San M, Adachi W, Tosuki H, Endo K, Mochida C, Yamada J, Maruyama K, Inoki K, Tanifuji N, Terai K, Suzuki S, Sano Y, Inatomi T, Sotozono C, Yokoi N, Nishida K, Quantock AJ, Cooper L, Fullwood NJ.
Ocular surface reconstruction by tissue engineering.
J Jap Ophthalmol Soc 2002; 106:837-869. 

Quantock AJ, Koizumi N, Kinoshita S.
Limbal stem cell deficiencies and ocular surface reconstruction.
Optometry Today 2002, 

Meek KM, Quantock AJ.
The use of x-ray scattering techniques to determine corneal ultrastructure.
Prog Ret Eye Res 2001; 20:95-137.

Kinoshita S, Adachi W, Sotozono C, Nishida K, Yokoi N, Quantock AJ, Okubo K.
Characteristics of the ocular surface epithelium.
Prog Ret Eye Res 2001; 20:639-673.

Sugita J, Yokoi N, Fullwood NJ, Quantock AJ, Takada Y, Nakamura Y, Kinoshita S.
The detection of bacteria and bacterial biofilms in punctal plug holes.
Cornea 2001;20:362-365. 

Quantock AJ, Meek KM, Chakravarti S.
An x-ray diffraction investigation of corneal structure in lumican-deficient mice.
Investigative Ophthalmology & Visual Science.2001; 42:1750-1756. 

Quantock AJ, Walters HJ.
Corneal dystrophies and mutations in the BIG-H3 gene.
Optometry Today 2001, 16, 24-29.