Prof Wolfgang Drexler
I am Link Chair Professor of Biomedical Imaging and Head of the Biomedical Imaging Group at the School of Optometry and Vision Sciences. My research plans involve multidisciplinary research collaborations across a wide range of disciplines to develop in vivo three-dimensional subcellular, molecular and functional imaging technology that is of significant diagnostic value.
So far my group has played a leading role in the development of optical coherence tomography (OCT), an optical medical diagnostic imaging modality which enables non-invasive high resolution in vivo three-dimensional tomographic visualization of internal microstructure in biological systems. During my stay at MIT, Cambridge, USA, I have initiated pioneering work in ultrahigh resolution OCT, approaching resolution levels of conventional histopathology, enabling optical biopsy and the first demonstration of in vivo subcellular and retinal ultrahigh resolution OCT (published in Nature Medicine in 2001).
Since then my research group has been involved in the development and commercialization of compact ultrabroad bandwidth laser technology for biomedical applications as well as in the development of ultrahigh resolution OCT technology for clinical applications in ophthalmology, dermatology, gastroenterology and neurology. My group has accomplished pioneering work in three dimensional adaptive optics ultrahigh resolution OCT for cellular resolution retinal imaging, novel full field OCT technology for high speed volumetric, scanner less biomedical imaging and in the development of functional extensions of OCT for non-invasive depth resolved detection of retinal physiology (optophysiology published in PNAS 2006) and metabolic tissue information.