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Supporting palliative care patients

23 November 2010

TRAD Alliance logo

A leading University palliative care expert will this week launch an international alliance of healthcare experts to lead research in the management of blood clots in patients with incurable diseases.

Dr Simon Noble, a clinical Senior Lecturer in Palliative Medicine, School of Medicine will lead the inaugural meeting of the Thrombosis Research in Advanced Disease (TRAD) Alliance – an alliance of some of Europe’s leading experts in managing treatment of blood clots in patients with incurable illnesses, like cancer.

"There is a massive gap in our knowledge of how best to treat patients with thrombosis, especially palliative patients with incurable diseases like cancer.

"With developments in the management of incurable malignant and non-malignant disease, it means that patients are living longer and the population of these patients will increase" according to Dr Noble.

Thromboembolism is the combination of thrombosis and its main complication, embolism – where the formation of a blood clot inside a blood vessel obstructs the flow of blood.

Dr Simon NobleDr Simon Noble

If the clot breaks free, the clot may travel to the lungs and form a pulmonary embolus which can prove fatal. The treatment of thrombosis is well established in healthy patients – but there is a limited knowledge of the treatment of palliative care patients.

The TRAD alliance brings some of the world’s experts to Cardiff to help find new ways of investigating the condition and disseminating new scientific research. A key part of the conference is a roundtable of experts who will also critically evaluate current practice guidelines and identify what research in necessary in this area.

Working with the University’s South East Wales Trials Unit and Hull/York Medical School the Alliance hopes to identify and then lead a series of clinical trials designed to lead new research in this area.

"These patients are more often the most vulnerable and present the most complex challenges in thrombosis treatment – yet, current research has left their needs unmet.

"It’s vital that we address this gap, for the sake of some our most vulnerable patients." Dr Noble added.

The Inaugural meeting of the Thrombosis Research in Advanced Disease Alliance (TRAD) takes place on Wednesday 24th November at the Holland House Hotel, Cardiff.

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