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20 November 2007
Focus On Genetics also features articles on: Genetics in Medicine, the Wales Gene Park, The "Impossible" breakthrough, Stopping the cancer "clock", Getting to grips with depression and Facing moral dilemmas.
Professor Julian Sampson, School of Medicine, became interested in the potential of genetics in medicine over two decades ago while involved in the treatment of children with cancer. "It was clear that changes in genes — sometimes inherited, sometimes occurring out of the blue — were causing the initiation and growth of tumours in these patients" he says. "I became interested in the part genetics has to play in determining health and disease."
Since then Professor Sampson has identified genes that cause a range of diseases from bowel cancer to kidney failure and has developed accurate diagnostic tests for them.
Now he is exploring the use of novel treatments that replace the action of the damaged genes using drugs.
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