Psychological medicine and clinical neurosciences

Research aimed at understanding the fundamental mechanisms underlying major psychiatric and neurological disorders.

There are programmes of work on schizophrenia, bipolar disorder, depression in children and adolescents, ADHD, Alzheimer's disease, Parkinson's disease, Huntington's disease, multiple sclerosis and epilepsy among others.

There is a major focus on genetics and genomics but also interest in brain imaging, epidemiology, animal models and cell biology. In addition, there is also work on psychoeducation, health services, research and public engagement.

The majority of the research is undertaken at the MRC Centre for Neuropsychiatric Genetics and Genomics (MRC CNGG).

Research themes

Brain tissue

Psychosis and major affective disorders

We are working to learn how genetic and environmental factors interact to cause major psychotic and mood disorders, such as schizophrenia and bipolar disorder.

Young teenage boy

Developmental disorders

We are researching how genetics and environment interact to lead to developmental disorders like ADHD and autism, and the causes of childhood depression.

Elderly man

Neurodegenerative disorders

We are working to develop better treatments and support for conditions including Alzheimer's, Huntington's and Parkinson's.