Microbial Disease
Confocal laser scanning microscopy showing Candida albicans (red) infection of a reconstituted human oral epithelium.
Key findings, achievements and areas of work
- Characterisation of the role of micro-organisms and host cell interaction in impaired healing (£425K Norwegian Research Council)
- The development of novel polymers, preventing biofilm formation (£76K DoH) and novel approaches to the management of oral diseases e.g. orofacial herpes (£166K GSK)
- The development of novel in vitro models to study skin/pathogen interaction and screen antimicrobial agents (£285K Johnson & Johnson; 2005 ETRS Young Investigator Award)
- Rationalisation of antibiotic prescribing for acute oral conditions in primary care (£197K NHS R&D)
- Molecular identification and pathogenicity of candida and clinical associations with disease
- Molecular detection of micro-organisms within oral squamous cell carcinoma
Group Members
Peptide nucleic acid (PNA)-FISH showing differentiation of Pseudomonas aeruginosa (yellow), Staphylococcus aureus (purple) and Microcoocus luteus (red).
- Mrs Sarah Bamford - Research Technician
- Mrs Charlotte Emanuel - Clinical Lecturer
- Dr Elaine Ferguson - Postdoctoral Research Scientist
- Dr Katja Hill - Senior Research Fellow
- Dr Sam J Hooper - Postdoctoral Researcher
- Prof Michael A O Lewis - Professor of Oral Medicine/Head of Oral Surgery Medicine & Pathology
- Mr A John C Potts - Consultant in Oral Pathology
- Professor Phil Stephens - Professor of Cell Biology, Vice Dean (Research)
- Professor David Thomas - Professor of Oral Surgery
- Dr David Williams - Reader in Oral Microbiology
- Dr Melanie J Wilson - Senior Lecturer/Honorary Consultant in Oral Microbiology