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Dr Matthew Locke 

Research Projects

  • Predominately involved in studying pluripotent stem cell induction from the readily accessible oral mucosal tissues. Through knowledge of the differential characteristics of oral mucosal lamina propria cells we believe that they will make particularly receptive cells for iPS derivation.
  • Role of fibroblast extracellular matrix in regulation of epithelial cells in health and disease, supported by Action Medical Research funding.
  • Oral fibroblast phenotype stability in-vitro - supported by The Oral and Dental Research Trust, Proctor and Gamble Research Awards.
  • Ex-vivo models for the biological testing of new and novel dental restorative materials.