![Robert Andrews](https://profiles-cardiff.imgix.net/attachments/223?w=200&h=200&auto=format&crop=faces&fit=crop&q=90")
Dr Robert Andrews
Senior Lecturer
- AndrewsR9@caerdydd.ac.uk
- +44 29206 87359
- Adeilad Ymchwil Cardiofasgwlaidd Syr Geraint Evans, Ystafell 1/14, Ysbyty Athrofaol Cymru, Parc y Mynydd Bychan, Caerdydd, CF14 4XN
Trosolwyg
I provide analysis support and teaching for data-driven research within the Systems Immunity Research Institute and the College of Biomedical and Lift Sciences. My projects include: ‘omic analysis, analysis coaching, data clinics, establishing research networks and infrastructure.
Cyhoeddiad
2024
- Czubala, M. A. et al. 2024. Tissue-specific transcriptional programming of macrophages controls the microRNA transcriptome targeting multiple functional pathways. Journal of Biological Chemistry, article number: 107244. (10.1016/j.jbc.2024.107244)
- Nieto-Rosado, M. et al. 2024. Colonisation of hospital surfaces from low- and middle-income countries by extended spectrum β-lactamase- and carbapenemase-producing bacteria. Nature Communications 15, article number: 2758. (10.1038/s41467-024-46684-z)
- Cabezas De La Fuente, D. et al. 2024. Impaired oxysterol-liver X receptor signaling underlies aberrant cortical neurogenesis in a human stem cell model of neurodevelopmental disorder. Cell Reports 43(3), article number: 113946. (10.1016/j.celrep.2024.113946)
2023
- Conroy, M. J. et al. 2023. LIPID MAPS: Update to databases and tools for the lipidomics community. Nucleic Acids Research, article number: gkad896. (10.1093/nar/gkad896)
- Hanna, S. J. et al. 2023. Single-cell RNAseq identifies clonally expanded antigen-specific T-cells following intradermal injection of gold nanoparticles loaded with diabetes autoantigen in humans. Frontiers in Immunology 14, article number: 1276255. (10.3389/fimmu.2023.1276255)
- Millrine, D. et al. 2023. Th1 cells alter the inflammatory signature of IL-6 by channeling STAT transcription factors to Alu-like retroelements. The Journal of Immunology 211(2), pp. 274-286. (10.4049/jimmunol.2300114)
- Clement, M. et al. 2023. Inhibitory IL-10-producing CD4+ T cells are T-bet-dependent and facilitate cytomegalovirus persistence via coexpression of arginase-1. eLife 12, article number: e79165. (10.7554/eLife.79165)
- Baldwin, A. et al. 2023. Storage of halved strawberry fruits affects aroma, phytochemical content and gene expression, and is affected by pre-harvest factors. Frontiers in Plant Science 14, article number: 1165056. (10.3389/fpls.2023.1165056)
- Parkinson, E. et al. 2023. Gene filtering strategies for machine learning guided biomarker discovery using neonatal sepsis RNA-seq data. Frontiers in Genetics 14, article number: 1158352. (10.3389/fgene.2023.1158352)
- Oruganti, S. et al. 2023. Immune and metabolic markers for identifying and investigating severe Coronavirus disease and Sepsis in children and young people (pSeP/COVID ChYP study): protocol for a prospective cohort study. BMJ Open 13, article number: e067002. (10.1136/bmjopen-2022-067002)
- Rastogi, N. et al. 2023. Nuclear factor I-C overexpression promotes monocytic development and cell survival in acute myeloid leukemia. Leukemia 37, pp. 276-287. (10.1038/s41375-022-01801-z)
2022
- Ni, Z. et al. 2022. Guiding the choice of informatics software and tools for lipidomics research applications. Nature Methods 20(2), pp. 193-204. (10.1038/s41592-022-01710-0)
- Carvalho, M. J. et al. 2022. Antibiotic resistance genes in the gut microbiota of mothers and linked neonates with or without sepsis from low- and middle-income countries. Nature Microbiology 7, pp. 1337-1347. (10.1038/s41564-022-01184-y)
- Sands, K. et al. 2022. Characterisation of Staphylococci species from neonatal blood cultures in low- and middle-income countries. BMC Infectious Diseases 22(1), article number: 593. (10.1186/s12879-022-07541-w)
- Takala, R. et al. 2022. Pinolenic acid exhibits Anti-inflammatory and Anti-atherogenic effects in Peripheral blood- derived Monocytes from patients with Rheumatoid Arthritis. Scientific Reports 12, article number: 8807. (10.1038/s41598-022-12763-8)
- Ponsford, M. J. et al. 2022. Examining the utility of extended laboratory panel testing in the emergency department for risk stratification of patients with COVID-19: a single-centre retrospective service evaluation. Journal of Clinical Pathology 75(4), pp. 255-262. (10.1136/jclinpath-2020-207157)
- Takala, R., Ramji, D. P., Andrews, R., Zhou, Y., Burston, J. and Choy, E. 2022. Anti-inflammatory and immunoregulatory effects of pinolenic acid in rheumatoid arthritis. Rheumatology 61(3), pp. 992-1004. (10.1093/rheumatology/keab467)
- Khan, U. B., Jauneikaite, E., Andrews, R., Chalker, V. J. and Spiller, O. B. 2022. Identifying large-scale recombination and capsular switching events in Streptococcus agalactiae strains causing disease in adults in the UK between 2014 and 2015. Microbial Genomics 8(3), article number: 783. (10.1099/mgen.0.000783)
- Misheva, M. et al. 2022. Oxylipin metabolism is controlled by mitochondrial β-oxidation during bacterial inflammation. Nature Communications 13(1), article number: 139. (10.1038/s41467-021-27766-8)
2021
- Chakraborty, M. et al. 2021. nSeP: immune and metabolic biomarkers for early detection of neonatal sepsis-protocol for a prospective multicohort study. BMJ Open 11(12), article number: e050100. (10.1136/bmjopen-2021-050100)
- Lu, Y. et al. 2021. Single-nucleus RNA sequencing identifies new classes of proximal tubular epithelial cells in kidney fibrosis. Journal of the American Society of Nephrology 32(10), pp. 2501-2516. (10.1681/ASN.2020081143)
- Jones, R. E., Andrews, R., Holmans, P., Hill, M. and Taylor, P. R. 2021. Modest changes in Spi1 dosage reveal the potential for altered microglial function as seen in Alzheimer's disease. Scientific Reports 11(1), article number: 14935. (10.1038/s41598-021-94324-z)
- Hrastelj, J. et al. 2021. CSF-resident CD4+ T-cells display a distinct gene expression profile with relevance to immune surveillance and multiple sclerosis. Brain Communications (10.1093/braincomms/fcab155)
- Khalid, U. et al. 2021. Determination of a microRNA signature of protective kidney ischemic preconditioning originating from proximal tubules. Scientific Reports 11(1), article number: 9862. (10.1038/s41598-021-89195-3)
- Sands, K. et al. 2021. Characterization of antimicrobial resistant Gram-negative bacteria that cause neonatal sepsis in seven low and middle-income countries. Nature Microbiology 6, pp. 512–523. (10.1038/s41564-021-00870-7)
- Crittenden, S. et al. 2021. Prostaglandin E2 promotes intestinal inflammation via inhibiting microbiota-dependent regulatory T cells. Science Advances 7(7), article number: eabd7954. (10.1126/sciadv.abd7954)
- Tyrrell, V. J. et al. 2021. Lipidomic and transcriptional analysis of the Linoleoyl-omega-Hydroxyceramide biosynthetic pathway in human psoriatic lesions. Journal of Lipid Research 62, article number: 100094. (10.1016/j.jlr.2021.100094)
2020
- Pires, A. et al. 2020. Immune remodelling of the extracellular matrix drives loss of cancer stem cells and tumor rejection. Cancer Immunology Research 8(12), pp. 1520 - 1531. (10.1158/2326-6066.CIR-20-0070)
- Greenshields-Watson, A. et al. 2020. CD4 + T cells recognize conserved influenza A epitopes through shared patterns of V-Gene usage and complementary biochemical features. Cell Reports 32(2), article number: 107885. (10.1016/j.celrep.2020.107885)
- Meckelmann, S. W. et al. 2020. Metabolic dysregulation of the lysophospholipid/autotaxin axis in the chromosome 9p21 gene SNP rs10757274. Circulation: Genomic and Precision Medicine 13(3), pp. 149-164., article number: e002806. (10.1161/CIRCGEN.119.002806)
- Scurr, M. J. et al. 2020. Cancer antigen discovery is enabled by RNA-sequencing of highly purified malignant and non-malignant cells. Clinical Cancer Research (10.1158/1078-0432.CCR-19-3087)
2019
- Thompson, A. et al. 2019. The protective effect of inflammatory monocytes during systemic C. albicans infection is dependent on collaboration between C-type lectin-like receptors. PLoS Pathogens 15(6), article number: e1007850. (10.1371/journal.ppat.1007850)
- Twohig, J. P. et al. 2019. Activation of naïve CD4+ T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4+ T cells. Nature Immunology 20, pp. 458-470. (10.1038/s41590-019-0350-0)
- Allen-Redpath, K. et al. 2019. Phospholipid membranes drive abdominal aortic aneurysm development through stimulating coagulation factor activity. Proceedings of the National Academy of Sciences 116(16), pp. 8038-8047. (10.1073/pnas.1814409116)
- Liu, Z. et al. 2019. Circular RNA hsa_circ_001783 regulates breast cancer progression via sponging miR-200c-3p. Cell Death and Disease 10, article number: 55. (10.1038/s41419-018-1287-1)
- Lear, B. et al. 2019. De novo transcriptome analysis of peduncle necking in cut Rosa hybrida cultivar 'H30'. Acta Horticulturae 1263, pp. 351-358.
2018
- Kentala, H. et al. 2018. OSBP-related protein-2 (ORP2): a novel Akt effector that controls cellular energy metabolism. Cellular and Molecular Life Sciences 75(21), pp. 4041-4057.
- McCully, M. L. et al. 2018. CCR8 expression defines tissue-resident memory T cells in human skin. Journal of Immunology 200(5), pp. 1639-1650. (10.4049/jimmunol.1701377)
- McNamara, G. I., Creeth, H. D. J., Harrison, D. J., Tansey, K. E., Andrews, R. M., Isles, A. R. and John, R. M. 2018. Loss of offspring Peg3 reduces neonatal ultrasonic vocalizations and increases maternal anxiety in wild-type mothers. Human Molecular Genetics 27(3), pp. 440-450. (10.1093/hmg/ddx412)
- Kentala, H., Koponen, A., Kivelä, A. M., Andrews, R., Li, C., Zhou, Y. and Olkkonen, V. M. 2018. Analysis of ORP2 knockout hepatocytes uncovers a novel function in actin cytoskeletal regulation. FASEB Journal (10.1096/fj.201700604R)
2017
- Dovey, O. M. et al. 2017. Molecular synergy underlies the co-occurrence patterns and phenotype of NPM1-mutant acute myeloid leukemia. Blood 130(17), pp. 1911-1922. (10.1182/blood-2017-01-760595)
- Fisher, C., Andrews, R. and Skarnes, W. 2017. An efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers. Nucleic Acids Research (10.1093/nar/gkx811)
- Liao, C. et al. 2017. Peritoneal macrophage heterogeneity is associated with different peritoneal dialysis outcomes. Kidney International 91(5), pp. 1088-1103. (10.1016/j.kint.2016.10.030)
Articles
- Czubala, M. A. et al. 2024. Tissue-specific transcriptional programming of macrophages controls the microRNA transcriptome targeting multiple functional pathways. Journal of Biological Chemistry, article number: 107244. (10.1016/j.jbc.2024.107244)
- Nieto-Rosado, M. et al. 2024. Colonisation of hospital surfaces from low- and middle-income countries by extended spectrum β-lactamase- and carbapenemase-producing bacteria. Nature Communications 15, article number: 2758. (10.1038/s41467-024-46684-z)
- Cabezas De La Fuente, D. et al. 2024. Impaired oxysterol-liver X receptor signaling underlies aberrant cortical neurogenesis in a human stem cell model of neurodevelopmental disorder. Cell Reports 43(3), article number: 113946. (10.1016/j.celrep.2024.113946)
- Conroy, M. J. et al. 2023. LIPID MAPS: Update to databases and tools for the lipidomics community. Nucleic Acids Research, article number: gkad896. (10.1093/nar/gkad896)
- Hanna, S. J. et al. 2023. Single-cell RNAseq identifies clonally expanded antigen-specific T-cells following intradermal injection of gold nanoparticles loaded with diabetes autoantigen in humans. Frontiers in Immunology 14, article number: 1276255. (10.3389/fimmu.2023.1276255)
- Millrine, D. et al. 2023. Th1 cells alter the inflammatory signature of IL-6 by channeling STAT transcription factors to Alu-like retroelements. The Journal of Immunology 211(2), pp. 274-286. (10.4049/jimmunol.2300114)
- Clement, M. et al. 2023. Inhibitory IL-10-producing CD4+ T cells are T-bet-dependent and facilitate cytomegalovirus persistence via coexpression of arginase-1. eLife 12, article number: e79165. (10.7554/eLife.79165)
- Baldwin, A. et al. 2023. Storage of halved strawberry fruits affects aroma, phytochemical content and gene expression, and is affected by pre-harvest factors. Frontiers in Plant Science 14, article number: 1165056. (10.3389/fpls.2023.1165056)
- Parkinson, E. et al. 2023. Gene filtering strategies for machine learning guided biomarker discovery using neonatal sepsis RNA-seq data. Frontiers in Genetics 14, article number: 1158352. (10.3389/fgene.2023.1158352)
- Oruganti, S. et al. 2023. Immune and metabolic markers for identifying and investigating severe Coronavirus disease and Sepsis in children and young people (pSeP/COVID ChYP study): protocol for a prospective cohort study. BMJ Open 13, article number: e067002. (10.1136/bmjopen-2022-067002)
- Rastogi, N. et al. 2023. Nuclear factor I-C overexpression promotes monocytic development and cell survival in acute myeloid leukemia. Leukemia 37, pp. 276-287. (10.1038/s41375-022-01801-z)
- Ni, Z. et al. 2022. Guiding the choice of informatics software and tools for lipidomics research applications. Nature Methods 20(2), pp. 193-204. (10.1038/s41592-022-01710-0)
- Carvalho, M. J. et al. 2022. Antibiotic resistance genes in the gut microbiota of mothers and linked neonates with or without sepsis from low- and middle-income countries. Nature Microbiology 7, pp. 1337-1347. (10.1038/s41564-022-01184-y)
- Sands, K. et al. 2022. Characterisation of Staphylococci species from neonatal blood cultures in low- and middle-income countries. BMC Infectious Diseases 22(1), article number: 593. (10.1186/s12879-022-07541-w)
- Takala, R. et al. 2022. Pinolenic acid exhibits Anti-inflammatory and Anti-atherogenic effects in Peripheral blood- derived Monocytes from patients with Rheumatoid Arthritis. Scientific Reports 12, article number: 8807. (10.1038/s41598-022-12763-8)
- Ponsford, M. J. et al. 2022. Examining the utility of extended laboratory panel testing in the emergency department for risk stratification of patients with COVID-19: a single-centre retrospective service evaluation. Journal of Clinical Pathology 75(4), pp. 255-262. (10.1136/jclinpath-2020-207157)
- Takala, R., Ramji, D. P., Andrews, R., Zhou, Y., Burston, J. and Choy, E. 2022. Anti-inflammatory and immunoregulatory effects of pinolenic acid in rheumatoid arthritis. Rheumatology 61(3), pp. 992-1004. (10.1093/rheumatology/keab467)
- Khan, U. B., Jauneikaite, E., Andrews, R., Chalker, V. J. and Spiller, O. B. 2022. Identifying large-scale recombination and capsular switching events in Streptococcus agalactiae strains causing disease in adults in the UK between 2014 and 2015. Microbial Genomics 8(3), article number: 783. (10.1099/mgen.0.000783)
- Misheva, M. et al. 2022. Oxylipin metabolism is controlled by mitochondrial β-oxidation during bacterial inflammation. Nature Communications 13(1), article number: 139. (10.1038/s41467-021-27766-8)
- Chakraborty, M. et al. 2021. nSeP: immune and metabolic biomarkers for early detection of neonatal sepsis-protocol for a prospective multicohort study. BMJ Open 11(12), article number: e050100. (10.1136/bmjopen-2021-050100)
- Lu, Y. et al. 2021. Single-nucleus RNA sequencing identifies new classes of proximal tubular epithelial cells in kidney fibrosis. Journal of the American Society of Nephrology 32(10), pp. 2501-2516. (10.1681/ASN.2020081143)
- Jones, R. E., Andrews, R., Holmans, P., Hill, M. and Taylor, P. R. 2021. Modest changes in Spi1 dosage reveal the potential for altered microglial function as seen in Alzheimer's disease. Scientific Reports 11(1), article number: 14935. (10.1038/s41598-021-94324-z)
- Hrastelj, J. et al. 2021. CSF-resident CD4+ T-cells display a distinct gene expression profile with relevance to immune surveillance and multiple sclerosis. Brain Communications (10.1093/braincomms/fcab155)
- Khalid, U. et al. 2021. Determination of a microRNA signature of protective kidney ischemic preconditioning originating from proximal tubules. Scientific Reports 11(1), article number: 9862. (10.1038/s41598-021-89195-3)
- Sands, K. et al. 2021. Characterization of antimicrobial resistant Gram-negative bacteria that cause neonatal sepsis in seven low and middle-income countries. Nature Microbiology 6, pp. 512–523. (10.1038/s41564-021-00870-7)
- Crittenden, S. et al. 2021. Prostaglandin E2 promotes intestinal inflammation via inhibiting microbiota-dependent regulatory T cells. Science Advances 7(7), article number: eabd7954. (10.1126/sciadv.abd7954)
- Tyrrell, V. J. et al. 2021. Lipidomic and transcriptional analysis of the Linoleoyl-omega-Hydroxyceramide biosynthetic pathway in human psoriatic lesions. Journal of Lipid Research 62, article number: 100094. (10.1016/j.jlr.2021.100094)
- Pires, A. et al. 2020. Immune remodelling of the extracellular matrix drives loss of cancer stem cells and tumor rejection. Cancer Immunology Research 8(12), pp. 1520 - 1531. (10.1158/2326-6066.CIR-20-0070)
- Greenshields-Watson, A. et al. 2020. CD4 + T cells recognize conserved influenza A epitopes through shared patterns of V-Gene usage and complementary biochemical features. Cell Reports 32(2), article number: 107885. (10.1016/j.celrep.2020.107885)
- Meckelmann, S. W. et al. 2020. Metabolic dysregulation of the lysophospholipid/autotaxin axis in the chromosome 9p21 gene SNP rs10757274. Circulation: Genomic and Precision Medicine 13(3), pp. 149-164., article number: e002806. (10.1161/CIRCGEN.119.002806)
- Scurr, M. J. et al. 2020. Cancer antigen discovery is enabled by RNA-sequencing of highly purified malignant and non-malignant cells. Clinical Cancer Research (10.1158/1078-0432.CCR-19-3087)
- Thompson, A. et al. 2019. The protective effect of inflammatory monocytes during systemic C. albicans infection is dependent on collaboration between C-type lectin-like receptors. PLoS Pathogens 15(6), article number: e1007850. (10.1371/journal.ppat.1007850)
- Twohig, J. P. et al. 2019. Activation of naïve CD4+ T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4+ T cells. Nature Immunology 20, pp. 458-470. (10.1038/s41590-019-0350-0)
- Allen-Redpath, K. et al. 2019. Phospholipid membranes drive abdominal aortic aneurysm development through stimulating coagulation factor activity. Proceedings of the National Academy of Sciences 116(16), pp. 8038-8047. (10.1073/pnas.1814409116)
- Liu, Z. et al. 2019. Circular RNA hsa_circ_001783 regulates breast cancer progression via sponging miR-200c-3p. Cell Death and Disease 10, article number: 55. (10.1038/s41419-018-1287-1)
- Lear, B. et al. 2019. De novo transcriptome analysis of peduncle necking in cut Rosa hybrida cultivar 'H30'. Acta Horticulturae 1263, pp. 351-358.
- Kentala, H. et al. 2018. OSBP-related protein-2 (ORP2): a novel Akt effector that controls cellular energy metabolism. Cellular and Molecular Life Sciences 75(21), pp. 4041-4057.
- McCully, M. L. et al. 2018. CCR8 expression defines tissue-resident memory T cells in human skin. Journal of Immunology 200(5), pp. 1639-1650. (10.4049/jimmunol.1701377)
- McNamara, G. I., Creeth, H. D. J., Harrison, D. J., Tansey, K. E., Andrews, R. M., Isles, A. R. and John, R. M. 2018. Loss of offspring Peg3 reduces neonatal ultrasonic vocalizations and increases maternal anxiety in wild-type mothers. Human Molecular Genetics 27(3), pp. 440-450. (10.1093/hmg/ddx412)
- Kentala, H., Koponen, A., Kivelä, A. M., Andrews, R., Li, C., Zhou, Y. and Olkkonen, V. M. 2018. Analysis of ORP2 knockout hepatocytes uncovers a novel function in actin cytoskeletal regulation. FASEB Journal (10.1096/fj.201700604R)
- Dovey, O. M. et al. 2017. Molecular synergy underlies the co-occurrence patterns and phenotype of NPM1-mutant acute myeloid leukemia. Blood 130(17), pp. 1911-1922. (10.1182/blood-2017-01-760595)
- Fisher, C., Andrews, R. and Skarnes, W. 2017. An efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers. Nucleic Acids Research (10.1093/nar/gkx811)
- Liao, C. et al. 2017. Peritoneal macrophage heterogeneity is associated with different peritoneal dialysis outcomes. Kidney International 91(5), pp. 1088-1103. (10.1016/j.kint.2016.10.030)
Addysgu
Rwy'n Gymrawd Addysg Uwch Uwch ac yn Hyfforddwr Carpentries ac mae gennyf hanes hir o ddysgu sgiliau data i ymchwilwyr yn y Gwyddorau Bywyd, gan gynnwys 13 mlynedd gyda Chyrsiau Uwch Ymddiriedolaeth Wellcome. Ar hyn o bryd, rwy'n arwain addysgu ac asesu ar gyfer 3 modiwl ar ein rhaglenni MSc mewn Biowybodeg, Imiwnoleg Glinigol Gymhwysol ac Arbrofol a Genomeg Meddygol, arbenigo mewn omeg a data TEG.
Mae'r gwobrau hyfforddi yn cynnwys cyd-arwain ar Gymrodoriaeth Hyfforddiant DaSH ELIXIR-UK (2021, £0.7M) ac arweinydd modiwl mewn Genomeg Addysg a Hyfforddiant ar gyfer Addysg a Gwella Iechyd Cymru (AaGIC) (2023, £0.9M).
Bywgraffiad
Dyfarniadau
Darparu modiwlau ôl-raddedig mewn Gwasanaethau Addysg a Hyfforddiant Genomeg, Addysg a Gwella Iechyd Cymru (AaGIC), Derek Blake (1), Nigel Williams, Ann Taylor, Ric Anney, Tom Connor (2), Hywel Williams (3), Zara Poghosyan (4), Nicki Taverner (5), Robert Andrews (6). £0.9M Ebrill 2023 - Ebrill 2027
UKRI-MRC, Grant Prosiect Protein tyrosine phosphatases fel rheostatau o signalau cytokine Jak-STAT a phenderfynyddion heterogenedd clefyd. SA. Jones, NM Williams, GW Jones, R Andrews, B. Szomolay. £1.02,M. Medi 2022- Medi 2025
ELIXIR Curadu llwybrau lipid gan arbenigwyr parth i gynhyrchu adnoddau bioleg mynediad agored. R Andrews (PI), V O'Donnell, M Conroy, E Willighagen €0.1M Ionawr 2022 - Mehefin 2023
Ysgolheigion Arloesi UKRI. Hyfforddiant Stiwardiaeth Data FAIR Ebrill 2021 - Ebrill 2023. K Poterlowicz (coI), R Andrews (coI), C Goble, N Hall, S Sasone. £0.75M Ebrill 2021 - Ebrill 2023.
Sefydliad Prydeinig y Galon, Grant Rhaglen Penderfynu sut mae ffosffolipidau bioactif yn rheoleiddio datblygiad ymlediad aortig abdomenol a cheulo gan ddefnyddio dulliau amlomig V O'Donnell (PI) P Collins, V Jenkins, K Channon, R Lee, Z Mallatt, N Mutch, R Andrews, J Watkins (Cyd-Is), £1.2M. Maw 2021- Maw 2026
