Yr Athro Michael O'Donovan

2024

• González-Peñas, J. et al. 2024. Accelerated cortical thinning in schizophrenia is associated with rare and common predisposing variation to schizophrenia and neurodevelopmental disorders. Biological Psychiatry (10.1016/j.biopsych.2024.03.011)
• Kappel, D. et al. 2024. Rare variants in pharmacogenes influence clozapine metabolism in individuals with schizophrenia. European Neuropsychopharmacology 80, pp. 47-54. (10.1016/j.euroneuro.2023.12.007)
• Legge, S. et al. 2024. An assessment of the genetic and phenotypic features of Schizophrenia in the UK biobank. JAMA Psychiatry
• Dennison, C. et al. 2024. Stratifying early-onset emotional disorders: using genetics to assess persistence in young people of European and South Asian ancestry. Journal of Child Psychology and Psychiatry 65(1), pp. 42-51. (10.1111/jcpp.13862)
• D'Andrea, G. et al. 2024. Variation of subclinical psychosis across 16 sites in Europe and Brazil: findings from the multi-national EU-GEI study. Psychological Medicine (10.1017/S0033291723003781)
• Koch, E. et al. 2024. How real-world data can facilitate the development of precision medicine treatment in psychiatry. Biological Psychiatry (10.1016/j.biopsych.2024.01.001)

2023

• Clifton, N. E., Lin, J. Q., Holt, C. E., O’Donovan, M. C. and Mill, J. 2023. Enrichment of the local synaptic translatome for genetic risk associated with schizophrenia and autism spectrum disorder. Biological Psychiatry (10.1016/j.biopsych.2023.12.006)
• Wang, S. et al. 2023. Rare X-linked variants carry predominantly male risk in Autism, Tourette Syndrome, and ADHD. Nature Communications 14, article number: 8077. (10.1038/s41467-023-43776-0)
• Spinazzola, E. et al. 2023. The association between reasons for first using cannabis, later pattern of use, and risk of first-episode psychosis: the EU-GEI case-control study. Psychological Medicine 53(15), pp. 7418-7427. (10.1017/S0033291723001071)
• Shakeshaft, A., Martin, J., Dennison, C. A., Riglin, L., Lewis, C. M., O'Donovan, M. and Thapar, A. 2023. Estimating the impact of transmitted and non-transmitted psychiatric and neurodevelopmental polygenic scores on youth emotional problems. Molecular Psychiatry (10.1038/s41380-023-02319-1)
• Yuan, K. et al. 2023. Fine-mapping across diverse ancestries drives the discovery of putative causal variants underlying human complex traits and diseases. European Neuropsychopharmacology 75(Supp 1), pp. S6-S7. (10.1016/j.euroneuro.2023.08.021)
• Lock, S. K. et al. 2023. Mediation and longitudinal analysis to interpret the association between clozapine pharmacokinetics, pharmacogenomics, and absolute neutrophil count. Schizophrenia 9, article number: 74. (10.1038/s41537-023-00404-6)
• Toste, C., O'Donovan, M. and Bray, N. 2023. Mapping microRNA expression quantitative trait loci in the prenatal human brain implicates miR-1908-5p expression in bipolar disorder and other brain-related traits. Human Molecular Genetics 32(20), pp. 2941-2949., article number: ddad118. (10.1093/hmg/ddad118)
• van der Meer, D. et al. 2023. Clustering schizophrenia genes by their temporal expression patterns aids functional interpretation. Schizophrenia Bulletin: The Journal of Psychoses and Related Disorders (10.1093/schbul/sbad140)
• Doherty, A., O'Donovan, M., Hamshere, M., Jones, I., Owen, M. and Walters, J. 2023. Genome-wide association study meta-analysis of suicide attempt identifies twelve genome-wide significant loci and implicates genetic risks for specific health factors. The American Journal of Psychiatry 180(10), pp. 723-738. (10.1176/appi.ajp.21121266)
• Clifton, N., Schulmann, A., Schizophrenia Working Group of the Psychiatric Genomics Consorti, ., Holmans, P., O'Donovan, M. and Vawter, M. 2023. The relationship between case-control differential gene expression from brain tissue and genetic associations in schizophrenia. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 192(5-6), pp. 85-92. (10.1002/ajmg.b.32931)
• Owen, M., Legge, S., Rees, E., Walters, J. and O'Donovan, M. 2023. Genomic findings in schizophrenia and their implications. Molecular Psychiatry 28, pp. 3638-3647. (10.1038/s41380-023-02293-8)
• Le Guen, Y. et al. 2023. Multiancestry analysis of the HLA locus in Alzheimer’s and Parkinson’s diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes. Proceedings of the National Academy of Sciences 120(36), article number: e2302720120. (10.1073/pnas.2302720120)
• Ollà, I. et al. 2023. Pathogenic mis-splicing of CPEB4 in schizophrenia. Biological Psychiatry 94(4), pp. 341-351. (10.1016/j.biopsych.2023.03.010)
• Maury, E. A. et al. 2023. Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions. Cell Genomics 3(8), article number: 100356. (10.1016/j.xgen.2023.100356)
• Allardyce, J. et al. 2023. Specificity of polygenic signatures across symptom dimensions in bipolar disorder: an analysis of UK Bipolar Disorder Research Network data. The Lancet Psychiatry 10(8), pp. 623-631. (10.1016/S2215-0366(23)00186-4)
• Lewis, K. et al. 2023. The dynamic interplay between sleep and mood: an intensive longitudinal study of individuals with bipolar disorder. Psychological Medicine 53(8), pp. 3345-3354. (10.1017/S0033291721005377)
• Rodriguez, V. et al. 2023. Use of multiple polygenic risk scores for distinguishing schizophrenia-spectrum disorder and affective psychosis categories in a first-episode sample; the EU-GEI study. Psychological Medicine 53(8), pp. 3396-3405. (10.1017/S0033291721005456)
• Demontis, D. et al. 2023. Author Correction: Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains. Nature Genetics 55, article number: 730. (10.1038/s41588-023-01350-w)
• Johnson, E. C. et al. 2023. Investigation of convergent and divergent genetic influences underlying schizophrenia and alcohol use disorder. Psychological Medicine 53(4), pp. 1196-1204. (10.1017/S003329172100266X)
• Lynham, A. J. et al. 2023. DRAGON-Data: A platform and protocol for integrating genomic and phenotypic data across large psychiatric cohorts. BJPsych Open 9(2), article number: e32. (10.1192/bjo.2022.636)
• Pardinas, A. F. et al. 2023. Pharmacokinetics and pharmacogenomics of clozapine in an ancestrally diverse sample: a longitudinal analysis and genome-wide association study using UK clinical monitoring data. The Lancet Psychiatry 10(3), pp. 209-219. (10.1016/S2215-0366(23)00002-0)
• Dimitriadis, S. I. et al. 2023. Genetic risk for schizophrenia is associated with increased proportion of indirect connections in brain networks revealed by a semi-metric analysis: evidence from population sample stratified for polygenic risk. Cerebral Cortex 33(6), pp. 2997-3011. (10.1093/cercor/bhac256)
• Liu, D. et al. 2023. Schizophrenia risk conferred by rare protein-truncating variants is conserved across diverse human populations. Nature Genetics 55, pp. 369-376. (10.1038/s41588-023-01305-1)
• Demontis, D. et al. 2023. Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains. Nature Genetics 55, pp. 198-208. (10.1038/s41588-022-01285-8)
• Ajnakina, O. et al. 2023. Development and validation of predictive model for a diagnosis of first episode psychosis using the multinational EU-GEI case-control study and modern statistical learning methods.. Schizophrenia Bulletin Open 4(1), article number: sgad008. (10.1093/schizbullopen/sgad008)
• Cameron, D. et al. 2023. Single nuclei RNA sequencing of 5 regions of the human prenatal brain implicates developing neuron populations in genetic risk for schizophrenia. Biological Psychiatry 93, pp. 157-166. (10.1016/j.biopsych.2022.06.033)
• Kappel, D. B. et al. 2023. Genomic stratification of clozapine prescription patterns using schizophrenia polygenic scores. Biological Psychiatry 93, pp. 149-156. (10.1016/j.biopsych.2022.07.014)
• Martin, J. et al. 2023. Investigating direct and indirect genetic effects in attention-deficit/hyperactivity disorder using parent-offspring trios. Biological Psychiatry 93(1), pp. 37-44. (10.1016/j.biopsych.2022.06.008)
• Frei, O. et al. 2023. Improved functional mapping with GSA-MiXeR implicates biologically specific gene-sets and estimates enrichment magnitude. Nature Genetics

2022

• Crawford, K. et al. 2022. Golgi apparatus, endoplasmic reticulum and mitochondrial function implicated in Alzheimer's disease through polygenic risk and RNA sequencing. Molecular Psychiatry (10.1038/s41380-022-01926-8)
• Riglin, L. et al. 2022. Early manifestations of genetic liability for ADHD, autism and schizophrenia at ages 18 and 24 months. JCPP Advances 2(3), article number: e12093. (10.1002/jcv2.12093)
• Bracher-Smith, M. et al. 2022. Machine learning for prediction of schizophrenia using genetic and demographic factors in the UK Biobank. Schizophrenia Research 246, pp. 156-164. (10.1016/j.schres.2022.06.006)
• Richards, A. et al. 2022. Genetic liabilities differentiating bipolar disorder, schizophrenia and major depression and phenotypic heterogeneity in bipolar disorder. JAMA Psychiatry 79(10), pp. 1032-1039. (10.1001/jamapsychiatry.2022.2594)
• Creeth, H. D. J. et al. 2022. Ultrarare coding variants and cognitive function in schizophrenia. JAMA Psychiatry 79(10), pp. 963-970. (10.1001/jamapsychiatry.2022.2289)
• Riglin, L. et al. 2022. “Late-onset” ADHD symptoms in young adulthood: is this the same as child-onset ADHD?. Journal of Attention Disorders 26(10), pp. 1271-1282. (10.1177/10870547211066486)
• Paquin, V. et al. 2022. Age- and sex-specific associations between risk scores for schizophrenia and self-reported health in the general population. Social Psychiatry and Psychiatric Epidemiology (10.1007/s00127-022-02346-3)
• van Os, J. et al. 2022. Evidence, and replication thereof, that molecular-genetic and environmental risks for psychosis impact through an affective pathway. Psychological Medicine 52(10), pp. 1910-1922. (10.1017/S0033291720003748)
• Henquet, C. et al. 2022. A replication study of JTC bias, genetic liability for psychosis and delusional ideation. Psychological Medicine 52(9), pp. 1777-1783. (10.1017/S0033291720003578)
• Crawford, K. et al. 2022. Analysis of Alzheimer's disease Polygenic Risk Scores using RNA-sequencing provides further novel biological pathways. [Online]. medRxiv: Cold Spring Harbor Laboratory. (10.1101/2022.06.29.22276952) Available at: https://doi.org/10.1101/2022.06.29.22276952
• Morris, E., O'Donovan, M., Virani, A. and Austin, J. 2022. An ethical analysis of divergent clinical approaches to the application of genetic testing for autism and schizophrenia. Human Genetics 141, pp. 1069-1084. (10.1007/s00439-021-02349-1)
• Palmer, D. et al. 2022. Exome sequencing in bipolar disorder reveals AKAP11 as a risk gene shared with schizophrenia. Nature Genetics (10.1038/s41588-022-01034-x)
• Bellenguez, C. et al. 2022. New insights into the genetic etiology of Alzheimer's disease and related dementias. Nature Genetics 54(4), pp. 412-436. (10.1038/s41588-022-01024-z)
• Trubetskoy, V. et al. 2022. Mapping genomic loci prioritises genes and implicates synaptic biology in schizophrenia. Nature 604, pp. 502-508. (10.1038/s41586-022-04434-5)
• Singh, T., Schizophrenia Exome Meta-Analysis (SCHEMA) Consortium, ., Kirov, G., Rees, E., Walters, J., Owen, M. and O'Donovan, M. 2022. Rare coding variants in ten genes confer substantial risk for schizophrenia. Nature 604, pp. 509-516. (10.1038/s41586-022-04556-w)
• Lancaster, T., Dimitriadis, S., Perry, G., Zammit, S., O'Donovan, M. and Linden, D. 2022. Morphometric analysis of structural MRI using schizophrenia meta-analytic priors distinguish patients from controls in two independent samples and in a sample of individuals with high polygenic risk. Schizophrenia Bulletin 48(2), pp. 524-532., article number: sbab125. (10.1093/schbul/sbab125)
• Fusar-Poli, L. et al. 2022. Examining facial emotion recognition as an intermediate phenotype for psychosis: findings from the EUGEI study. Progress in Neuro-Psychopharmacology and Biological Psychiatry 113, article number: 110440. (10.1016/j.pnpbp.2021.110440)
• Mullins, N. et al. 2022. Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors. Biological Psychiatry 91(3), pp. 313-327. (10.1016/j.biopsych.2021.05.029)
• Jones, H. J. et al. 2022. Examining pathways between genetic liability for schizophrenia and patterns of tobacco and cannabis use in adolescence. Psychological Medicine 52(1), pp. 132-139. (10.1017/S0033291720001798)
• Vassos, E. et al. 2022. Lack of support for the genes by early environment interaction hypothesis in the pathogenesis of schizophrenia. Schizophrenia Bulletin 48(1), pp. 20-26. (10.1093/schbul/sbab052)
• Sanders, B. et al. 2022. Transcriptional programs regulating neuronal differentiation are disrupted in DLG2 knockout human embryonic stem cells and enriched for schizophrenia and related disorders risk variants. Nature Communications 13(1), article number: 27. (10.1038/s41467-021-27601-0)
• Pardinas, A. et al. 2022. Interaction testing and polygenic risk scoring to estimate the contribution of common genetic variants to treatment resistance in schizophrenia. JAMA Psychiatry 79(3), pp. 260-269. (10.1001/jamapsychiatry.2021.3799)

2021

• Dimitriadis, S. I. et al. 2021. Global brain flexibility during working memory is reduced in a high genetic risk group for schizophrenia. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging 6(12), pp. 1176-1184. (10.1016/j.bpsc.2021.01.007)
• Di Florio, A. et al. 2021. Post-partum psychosis and its association with bipolar disorder in the UK: a case-control study using polygenic risk scores. The Lancet Psychiatry 8(12), pp. 1045-1052. (10.1016/S2215-0366(21)00253-4)
• Kalman, J. L. et al. 2021. Characterisation of age and polarity at onset in bipolar disorder. The British Journal of Psychiatry 219(6), pp. 659-669. (10.1192/bjp.2021.102)
• Ajnakina, O. et al. 2021. Duration of untreated psychosis in first-episode psychosis is not associated with common genetic variants for major psychiatric conditions: results from the multi-center EU-GEI study. Schizophrenia Bulletin 47(6), pp. 1653-1662. (10.1093/schbul/sbab055)
• Dimitriadis, S. I. et al. 2021. Genetic risk for schizophrenia is associated with altered visually-induced gamma band activity: evidence from a population sample stratified polygenic risk. Translational Psychiatry 11, article number: 592. (10.1038/s41398-021-01678-z)
• Martin, J. et al. 2021. Sex differences in anxiety and depression in children with ADHD investigating genetic liability and comorbidity. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 186(7), pp. 412-422. (10.1002/ajmg.b.32842)
• Jia, X. et al. 2021. Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder. Molecular Psychiatry 26, pp. 5239-5250. (10.1038/s41380-020-01006-9)
• Dennison, C. et al. 2021. Risk factors, clinical features, and polygenic risk scores in schizophrenia and schizoaffective disorder depressive-type. Schizophrenia Bulletin 47(5), pp. 1375-1384. (10.1093/schbul/sbab036)
• Clifton, N. E. et al. 2021. Developmental profile of psychiatric risk associated with voltage-gated cation channel activity. Biological Psychiatry 90(6) (10.1016/j.biopsych.2021.03.009)
• Rees, E. et al. 2021. Schizophrenia, autism spectrum disorders and developmental disorders share specific disruptive coding mutations. Nature Communications 12, article number: 5353. (10.1038/s41467-021-25532-4)
• Martin, J. et al. 2021. Examining sex differences in neurodevelopmental and psychiatric genetic risk in anxiety and depression. PLoS ONE 16(9), article number: e0248254. (10.1371/journal.pone.0248254)
• Riglin, L. et al. 2021. ADHD and depression: investigating a causal explanation. Psychological Medicine 51(11), pp. 1890-1897. (10.1017/S0033291720000665)
• Quattrone, D. et al. 2021. The continuity of effect of schizophrenia polygenic risk score and patterns of cannabis use on transdiagnostic symptom dimensions at first-episode psychosis: findings from the EU-GEI study. Translational Psychiatry 11(1), article number: 423. (10.1038/s41398-021-01526-0)
• Legge, S. et al. 2021. Associations between schizophrenia polygenic liability, symptom dimensions, and cognitive ability in schizophrenia. JAMA Psychiatry 78(10), pp. 1143-1151. (10.1001/jamapsychiatry.2021.1961)
• Clifton, N. E. et al. 2021. Genetic association of FMRP targets with psychiatric disorders. Molecular Psychiatry 26, pp. 2977-2990. (10.1038/s41380-020-00912-2)
• Hubbard, L. et al. 2021. Rare copy number variations are associated with poorer cognition in schizophrenia. Biological Psychiatry 90(1), pp. 28-34. (10.1016/j.biopsych.2020.11.025)
• Byrne, E. et al. 2021. Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders. Molecular Psychiatry 26, pp. 2070-2081. (10.1038/s41380-020-0705-9)
• Hall, L. S. et al. 2021. Cis-effects on gene expression in the human prenatal brain associated with genetic risk for neuropsychiatric disorders. Molecular Psychiatry 26, pp. 2082-2088. (10.1038/s41380-020-0743-3)
• Amare, A. T. et al. 2021. Association of polygenic score for major depression with response to lithium in patients with bipolar disorder. Molecular Psychiatry 26, pp. 2457-2470. (10.1038/s41380-020-0689-5)
• Tigaret, C. M. et al. 2021. Neurotrophin receptor activation rescues cognitive and synaptic abnormalities caused by hemizygosity of the psychiatric risk gene Cacna1c. Molecular Psychiatry 26, pp. 1748-1760. (10.1038/s41380-020-01001-0)
• Mullins, N. et al. 2021. Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. Nature Genetics 53, pp. 817-829. (10.1038/s41588-021-00857-4)
• Peterson, R. E. et al. 2021. Genome-wide analyses of smoking behaviors in schizophrenia: findings from the Psychiatric Genomics Consortium. Journal of Psychiatric Research 137, pp. 215-225. (10.1016/j.jpsychires.2021.02.027)
• Riglin, L. et al. 2021. Investigating attention‐deficit hyperactivity disorder and autism spectrum disorder traits in the general population: What happens in adult life?. Journal of Child Psychology and Psychiatry 62(4), pp. 449-457. (10.1111/jcpp.13297)
• Willcocks, I. et al. 2021. Clozapine metabolism is associated with absolute neutrophil count in individuals with treatment-resistant schizophrenia. Frontiers in Pharmacology 12, article number: 658734. (10.3389/fphar.2021.658734)
• Konte, B. et al. 2021. HLA-DQB1 6672G>C (rs113332494) is associated with clozapine-induced neutropenia and agranulocytosis in individuals of European ancestry. Translational Psychiatry 11, article number: 214. (10.1038/s41398-021-01322-w)
• Tripoli, G. et al. 2021. Jumping to conclusions, general intelligence, and psychosis liability: findings from the multi-centre EU-GEI case-control study. Psychological Medicine 51(4), pp. 623-633. (10.1017/S003329171900357X)
• Dennison, C. A. et al. 2021. Association of genetic liability for psychiatric disorders with accelerometer-assessed physical activity in the UK Biobank. PLoS ONE 16(3), article number: e0249189. (10.1371/journal.pone.0249189)
• Erzin, G. et al. 2021. Examining the association between exposome score for schizophrenia and functioning in schizophrenia, siblings, and healthy controls: Results from the EUGEI study. European Psychiatry 64(1), article number: e25. (10.1192/j.eurpsy.2021.19)
• Smeland, O. B. et al. 2021. Genome-wide association analysis of Parkinson's disease and schizophrenia reveals shared genetic architecture and identifies novel risk loci. Biological Psychiatry 89(3), pp. 227-235. (10.1016/j.biopsych.2020.01.026)
• Owen, M. J. and O'Donovan, M. C. 2021. Large-scale genomics: a paradigm shift in psychiatry?. Biological Psychiatry 89, pp. 5-7. (10.1016/j.biopsych.2020.01.017)
• Hannon, E. et al. 2021. DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia. eLife 10, article number: e58430. (10.7554/eLife.58430)
• Chauquet, S., Zhu, Z., O'Donovan, M., Walters, J., Wray, N. and Shah, S. 2021. Investigating the potential effects of antihypertensive medication on psychiatric disorders: a mendelian randomisation study. JAMA Psychiatry 78(6), pp. 623-631. (10.1001/jamapsychiatry.2021.0005)
• Hasmi, L. et al. 2021. What makes the psychosis 'clinical high risk' state risky: psychosis itself or the co-presence of a non-psychotic disorder?. Epidemiology and Psychiatric Sciences 30, article number: e53. (10.1017/S204579602100041X)

2020

• Pries, L. et al. 2020. Association of recent stressful life events with mental and physical health in the context of genomic and exposomic liability for schizophrenia. JAMA Psychiatry 77(12), pp. 1296-1304. (10.1001/jamapsychiatry.2020.2304)
• Ward, J. et al. 2020. The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function. Molecular Psychiatry 25, pp. 3091-3099. (10.1038/s41380-019-0439-8)
• Pries, L. et al. 2020. Examining the independent and joint effects of genomic and exposomic liabilities for schizophrenia across the psychosis spectrum. Epidemiology and Psychiatric Sciences 29, article number: e182. (10.1017/S2045796020000943)
• Kendall, K. M. et al. 2020. Impact of schizophrenia genetic liability on the association between schizophrenia and physical illness: a data linkage study. BJPsych Open 6(6), article number: e139. (10.1192/bjo.2020.42)
• Legge, S. E. et al. 2020. The Duffy-null genotype and risk of infection. Human Molecular Genetics 29(20), pp. 3341-3349. (10.1093/hmg/ddaa208)
• Jones, H. J. et al. 2020. A Mendelian randomization study of the causal association between anxiety phenotypes and schizophrenia. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 183(6), pp. 360-369. (10.1002/ajmg.b.32808)
• van Os, J. et al. 2020. Replicated evidence that endophenotypic expression of schizophrenia polygenic risk is greater in healthy siblings of patients compared to controls, suggesting gene-environment interaction. The EUGEI study. Psychological Medicine 50(11), pp. 1884-1897. (10.1017/S003329171900196X)
• Wong, H., Wadon, M., Evans, A., Kirov, G., Modi, N., O'Donovan, M. and Thapar, A. 2020. Contribution of de novo and inherited rare copy number variants to very preterm birth. Journal of Medical Genetics 57(8), pp. 552-557. (10.1136/jmedgenet-2019-106619)
• Riglin, L. et al. 2020. Using genetics to examine a general liability to childhood psychopathology. Behavior Genetics 50, pp. 213-220. (10.1007/s10519-019-09985-4)
• Coleman, J. R. I. et al. 2020. Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank. Molecular Psychiatry 25, pp. 1430-1446. (10.1038/s41380-019-0546-6)
• Akingbuwa, W. A. et al. 2020. Genetic associations between childhood psychopathology and adult depression and associated traits in 42 998 individuals. JAMA Psychiatry 77(7), pp. 715-728. (10.1001/jamapsychiatry.2020.0527)
• Wong, H. S., Hopkins, L., O'Donovan, M. C., Thapar, A. and Modi, N. 2020. Pilot study to establish a prospective neonatal cohort: Study of Preterm Infants and Neurodevelopmental Genes (SPRING). Molecular Psychiatry 4(1), article number: e000648. (10.1136/bmjpo-2020-000648)
• Lee, S. C. et al. 2020. Area deprivation, urbanicity, severe mental illness and social drift — a population-based linkage study using routinely collected primary and secondary care data. Schizophrenia Research 220, pp. 130-140. (10.1016/j.schres.2020.03.044)
• Legge, S. et al. 2020. Clinical indicators of treatment-resistant psychosis. British Journal of Psychiatry 216(5), pp. 259-266. (10.1192/bjp.2019.120)
• Wadon, M., Modi, N., Wong, H., Thapar, A. and O'Donovan, M. 2020. Recent advances in the genetics of preterm birth. Annals of Human Genetics 84(3), pp. 205-213. (10.1111/ahg.12373)
• Martin, J. et al. 2020. A brief report: de novo copy number variants in children with attention deficit hyperactivity disorder. Translational Psychiatry 10, article number: 135. (10.1038/s41398-020-0821-y)
• Foley, C. et al. 2020. Identifying schizophrenia patients who carry pathogenic genetic copy number variants using standard clinical assessment: retrospective cohort study. British Journal of Psychiatry 216(5), pp. 275-279. (10.1192/bjp.2019.262)
• Szatkiewicz, J. P. et al. 2020. Characterization of single gene copy number variants in schizophrenia. Biological Psychiatry 87(8), pp. 736-744. (10.1016/j.biopsych.2019.09.023)
• Sullivan, S. A. et al. 2020. A population-based cohort study examining the incidence and impact of psychotic experiences from childhood to adulthood, and prediction of psychotic disorder. American Journal of Psychiatry 177(4), pp. 308-317. (10.1176/appi.ajp.2019.19060654)
• Richards, A. et al. 2020. The relationship between polygenic risk scores and cognition in schizophrenia. Schizophrenia Bulletin 46(2), pp. -. (10.1093/schbul/sbz061)
• Lewis, K. J. et al. 2020. Comparison of genetic liability for sleep traits among individuals with Bipolar Disorder I or II and control participants. JAMA Psychiatry 77(3), pp. 303-310. (10.1001/jamapsychiatry.2019.4079)
• Glanville, K. P. et al. 2020. Classical human leukocyte antigen alleles and C4 haplotypes are not significantly associated with depression. Biological Psychiatry 87(5), pp. 419-430. (10.1016/j.biopsych.2019.06.031)
• Rees, E. et al. 2020. De novo mutations identified by exome sequencing implicate rare missense variants in SLC6A1 in schizophrenia. Nature Neuroscience 23(2), pp. 179-184. (10.1038/s41593-019-0565-2)
• Hall, L. S. et al. 2020. A transcriptome-wide association study implicates specific pre- and post-synaptic abnormalities in schizophrenia. Human Molecular Genetics 29(1), pp. 159-167. (10.1093/hmg/ddz253)

2019

• Legge, S. E. et al. 2019. Association of genetic liability to psychotic experiences with neuropsychotic disorders and traits. JAMA Psychiatry 76(12), pp. 1256-1265. (10.1001/jamapsychiatry.2019.2508)
• Lam, M. et al. 2019. Comparative genetic architectures of schizophrenia in East Asian and European populations. Nature Genetics 51, pp. 1670-1678. (10.1038/s41588-019-0512-x)
• Lee, P. H. et al. 2019. Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders. Cell 179(7), pp. 1469-1482.e11. (10.1016/j.cell.2019.11.020)
• Escott-Price, V. et al. 2019. Polygenic risk for schizophrenia and season of birth within the UK Biobank cohort. Psychological Medicine 49(15), pp. 2499-2504. (10.1017/S0033291718000454)
• Chapman, R. M. et al. 2019. Convergent evidence that ZNF804A is a regulator of pre-messenger RNA processing and gene expression. Schizophrenia Bulletin 45(6), pp. 1267-1278. (10.1093/schbul/sby183)
• Toste, C. et al. 2019. No effect of genome-wide significant schizophrenia risk variation at the DRD2 locus on the allelic expression of DRD2 in post-mortem striatum. Molecular Neuropsychiatry 5(4), pp. 212-217. (10.1159/000501022)
• Sykes, L. et al. 2019. Genetic variation in the psychiatric risk gene CACNA1C modulates reversal learning across species. Schizophrenia Bulletin 45(5), pp. 1024-1032. (10.1093/schbul/sby146)
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• Mulllins, N. et al. 2019. GWAS of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores. American Journal of Psychiatry 176(8), pp. 651-660. (10.1176/appi.ajp.2019.18080957)
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• Rice, F., Riglin, L., Thapar, A. K., Heron, J., Anney, R., O'Donovan, M. C. and Thapar, A. 2019. Characterizing developmental trajectories and the role of neuropsychiatric genetic risk variants in early-onset depression. JAMA Psychiatry 76(3), pp. 306-313. (10.1001/jamapsychiatry.2018.3338)
• Legge, S. E. et al. 2019. A genome-wide association study in individuals of African ancestry reveals the importance of the Duffy-null genotype in the assessment of clozapine-related neutropenia. Molecular Psychiatry 24, pp. 328-337. (10.1038/s41380-018-0335-7)
• Kunkle, B. W. et al. 2019. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics 51(3), pp. 414-430. (10.1038/s41588-019-0358-2)
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2018

• Arnau-Soler, A. et al. 2018. Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder. PLoS ONE 13(12), article number: e0209160. (10.1371/journal.pone.0209160)
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• O'Brien, H. E. et al. 2018. Expression quantitative trait loci in the developing human brain and their enrichment in neuropsychiatric disorders. Genome Biology 19, article number: 194. (10.1186/s13059-018-1567-1)
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• Cooper, M. et al. 2018. Investigating late-onset ADHD: a population cohort investigation. Journal of Child Psychology and Psychiatry 59(10), pp. 1105-1113. (10.1111/jcpp.12911)
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• Fabbri, C. et al. 2018. Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: meta-analysis of data from genome-wide association studies. European Neuropsychopharmacology 28(8), pp. 945-954. (10.1016/j.euroneuro.2018.05.009)
• Donohoe, G. et al. 2018. Genetically predicted complement component 4A expression: effects on memory function and middle temporal lobe activation. Psychological Medicine 48(10), pp. 1608-1615. (10.1017/S0033291717002987)
• Guyatt, A. L. et al. 2018. Association of copy number variation across the genome with neuropsychiatric traits in the general population. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 177(5), pp. 489-502. (10.1002/ajmg.b.32637)
• Skene, N. G. et al. 2018. Genetic identification of brain cell types underlying schizophrenia. Nature Genetics 50, pp. 825-833. (10.1038/s41588-018-0129-5)
• Baker, E., Schmidt, K. M., Sims, R., O'Donovan, M. C., Williams, J., Holmans, P. and Escott-Price, V. 2018. POLARIS: polygenic LD-adjusted risk score approach for set-based analysis of GWAS data. Genetic Epidemiology 42(4), pp. 366-377. (10.1002/gepi.22117)
• Martin, J. et al. 2018. A genetic investigation of sex bias in the prevalence of attention-deficit/hyperactivity disorder. Biological Psychiatry 83(12), pp. 1044-1053. (10.1016/j.biopsych.2017.11.026)
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• Pardinas, A. F. et al. 2018. Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection. Nature Genetics 50, pp. 381-389. (10.1038/s41588-018-0059-2)
• Strawbridge, R. J. et al. 2018. Genome-wide analysis of self-reported risk-taking behaviour and cross-disorder genetic correlations in the UK Biobank cohort. Translational Psychiatry 8, article number: 39. (10.1038/s41398-017-0079-1)
• Allardyce, J. et al. 2018. Association between schizophrenia-related polygenic liability and the occurrence and level of mood-incongruent psychotic symptoms in bipolar disorder. JAMA Psychiatry 75(1), pp. 28-35. (10.1001/jamapsychiatry.2017.3485)

2017

• Green, E. K. et al. 2017. Genome-wide significant locus for Research Diagnostic Criteria Schizoaffective Disorder Bipolar type. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 174(8), pp. 767-771. (10.1002/ajmg.b.32572)
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• Ward, J. et al. 2017. Genome-wide analysis in UK Biobank identifies four loci associated with mood instability and genetic correlation with MDD, anxiety disorder and schizophrenia. Translational Psychiatry 7, article number: 1264. (10.1038/s41398-017-0012-7)
• Li, Z. et al. 2017. Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia. Nature Genetics 49, pp. 1576-1583. (10.1038/ng.3973)
• Leonenko, G. et al. 2017. Mutation intolerant genes and targets of FMRP are enriched for nonsynonymous alleles in schizophrenia. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 174(7), pp. 724-731. (10.1002/ajmg.b.32560)
• Legge, S. E. et al. 2017. Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia. Molecular Psychiatry 22, pp. 1502-1508. (10.1038/mp.2016.97)
• Riglin, L. et al. 2017. Investigating the genetic underpinnings of early-life irritability. Translational Psychiatry 7, article number: e1241. (10.1038/tp.2017.212)
• Sims, R. et al. 2017. Rare coding variants in PLCG2, ABI3 and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics 49, pp. 1373-1384. (10.1038/ng.3916)
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• Witt, S. H. et al. 2017. Genome-wide association study of borderline personality disorder reveals genetic overlap with the bipolar disorder, schizophrenia and major depression. Translational Psychiatry 7, article number: e1155.
• Hannon, E., Weedon, M., Bray, N., O'Donovan, M. and Mill, J. 2017. Pleiotropic effects of trait-associated genetic variation on DNA methylation: utility for refining GWAS loci. American Journal of Human Genetics 100(6), pp. 954-959. (10.1016/j.ajhg.2017.04.013)
• García-González, J. et al. 2017. Pharmacogenetics of antidepressant response: a polygenic approach. Progress in Neuro-Psychopharmacology and Biological Psychiatry 75, pp. 128-134. (10.1016/j.pnpbp.2017.01.011)
• McLaughlin, R. L. et al. 2017. Genetic correlation between amyotrophic lateral sclerosis and schizophrenia. Nature Communications 8, article number: 14774. (10.1038/ncomms14774)
• Riglin, L., Collishaw, S., Richards, A., Thapar, A., Maughan, B., O'Donovan, M. C. and Thapar, A. 2017. Schizophrenia polygenic risk score and psychotic risk detection - authors' reply. The Lancet Psychiatry 4(3), pp. 188-189. (10.1016/S2215-0366(17)30052-4)
• Clifton, N. E. et al. 2017. Schizophrenia copy number variants and associative learning. Molecular Psychiatry 22(2), pp. 178-182. (10.1038/mp.2016.227)
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• Lo, M. et al. 2017. Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders. Nature Genetics 49, pp. 152-156. (10.1038/ng.3736)
• Cosgrove, D. et al. 2017. MiR-137-derived polygenic risk: effects on cognitive performance in patients with schizophrenia and controls. Translational Psychiatry 7(1), pp. e1012. (10.1038/tp.2016.286)
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• Fabbri, C. et al. 2017. Consensus paper of the WFSBP Task Force on Genetics: genetics, epigenetics and gene expression markers of major depressive disorder and antidepressant response. World Journal of Biological Psychiatry 18(1), pp. 5-28. (10.1080/15622975.2016.1208843)
• Fraguas, D., Díaz-Caneja, C. M., State, M. W., O'Donovan, M. C., Gur, R. E. and Arango, C. 2017. Mental disorders of known aetiology and precision medicine in psychiatry: a promising but neglected alliance [Editorial]. Psychological Medicine 47(2), pp. 193-197. (10.1017/S0033291716001355)
• Riglin, L., Collishaw, S., Richards, A., Thapar, A. K., Maughan, B., O'Donovan, M. C. and Thapar, A. 2017. Schizophrenia risk alleles and neurodevelopmental outcomes in childhood: a population-based cohort study. Lancet Psychiatry 4(1), pp. 57-62. (10.1016/S2215-0366(16)30406-0)
• Sullivan, P. F. et al. 2017. Psychiatric genomics: an update and an agenda. American Journal of Psychiatry 175(1), pp. 15-27. (10.1176/appi.ajp.2017.17030283)

2016

• Riglin, L. et al. 2016. Association of genetic risk variants with attention-deficit/hyperactivity disorder trajectories in the general population. JAMA Psychiatry 73(12), pp. 1285-1292. (10.1001/jamapsychiatry.2016.2817)
• Whitton, L. et al. 2016. Cognitive analysis of schizophrenia risk genes that function as epigenetic regulators of gene expression. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 171(8), pp. 1170-1179. (10.1002/ajmg.b.32503)
• Thapar, A. et al. 2016. Psychiatric gene discoveries shape evidence on ADHD's biology. Molecular Psychiatry 21, pp. 1202-1207. (10.1038/mp.2015.163)
• Rees, E. et al. 2016. Analysis of intellectual disability copy number variants for association with schizophrenia. JAMA Psychiatry 73(9), pp. 963-969. (10.1001/jamapsychiatry.2016.1831)
• Mooney, M. A. et al. 2016. Pathway analysis in attention deficit hyperactivity disorder: an ensemble approach. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 171(6), pp. 815-826. (10.1002/ajmg.b.32446)
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• van Goozen, S. H. M. et al. 2016. Identifying mechanisms that underlie links between COMT genotype and aggression in male adolescents with ADHD. Journal of Child Psychology and Psychiatry 57(4), pp. 472-480. (10.1111/jcpp.12464)
• Singh, T. et al. 2016. Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders. Nature Neuroscience 19(4), pp. 571-577. (10.1038/nn.4267)
• Lawrie, S. M., O'Donovan, M. C., Saks, E., Burns, T. and Lieberman, J. A. 2016. Towards diagnostic markers for the psychoses. The Lancet Psychiatry 3(4), pp. 375-385. (10.1016/S2215-0366(16)00021-3)
• Carroll, L. S. et al. 2016. Mutation screening of SCN2A in schizophrenia and identification of a novel loss-of-function mutation. Psychiatric Genetics 26(2), pp. 60-65. (10.1097/YPG.0000000000000110)
• Lawrie, S. M., O'Donovan, M. C., Saks, E., Burns, T. and Lieberman, J. A. 2016. Improving classification of psychoses. The Lancet Psychiatry 3(4), pp. 367-374. (10.1016/S2215-0366(15)00577-5)
• Franke, B. et al. 2016. Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept. Nature Neuroscience 19(3), pp. 420-431. (10.1038/nn.4228)
• Singh, T. et al. 2016. Rare loss-of-function variants in KMT2F are associated with schizophrenia and developmental disorders. Nature Neuroscience 19, pp. 571-577. (10.1101/036384)
• Richards, A. et al. 2016. Exome arrays capture polygenic rare variant contributions to schizophrenia. Human Molecular Genetics 25(5), pp. 1001-1007. (10.1093/hmg/ddv620)
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• Bigdeli, T. B. et al. 2016. Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 171(2), pp. 276-289. (10.1002/ajmg.b.32402)
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• Hannon, E. et al. 2016. Methylation QTLs in the developing brain and their enrichment in schizophrenia risk loci. Nature Neuroscience 19(1), pp. 48-54. (10.1038/nn.4182)
• Jun, G. et al. 2016. A novel Alzheimer disease locus located near the gene encoding tau protein. Molecular Psychiatry 21, pp. 108-117. (10.1038/mp.2015.23)
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• Hubbard, L. et al. 2016. Evidence of common genetic overlap between schizophrenia and cognition. Schizophrenia Bulletin 42(3), pp. 832-842. (10.1093/schbul/sbv168)
• Pers, T. H., Timshel, P., Ripke, S., Sullivan, P. F., O'Donovan, M. C., Franke, L. and Hirschhorn, J. N. 2016. Comprehensive analysis of schizophrenia-associated loci highlights ion channel pathways and biologically plausible candidate causal genes. Human Molecular Genetics 25(6), pp. 1247-1254. (10.1093/hmg/ddw007)
• Corvin, A. and O'Donovan, M. C. 2016. Psychiatric genetics: what's new in 2015?. The Lancet Psychiatry 3(1), pp. 10-12. (10.1016/S2215-0366(15)00571-4)
• O'Donovan, M. C. and Owen, M. J. 2016. The implications of the shared genetics of psychiatric disorders. Nature Medicine 22, pp. 1214-1219. (10.1038/nm.4196)

2015

• Loh, P. et al. 2015. Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis. Nature Genetics 47, pp. 1385-1392. (10.1038/ng.3431)
• Tansey, K. E. et al. 2015. Common alleles contribute to schizophrenia in CNV carriers [Erratum]. Molecular Psychiatry 21, article number: 1153. (10.1038/mp.2015.170)
• Escott-Price, V., Kirov, G., Rees, E., Isles, A. R., Owen, M. J. and O'Donovan, M. C. 2015. No evidence for enrichment in schizophrenia for common allelic associations at imprinted loci. PLoS ONE 10(12), pp. -., article number: e0144172. (10.1371/journal.pone.0144172)
• Andreassen, O. A. et al. 2015. Correction: Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate. PLoS Genetics 11(11), article number: e1005544. (10.1371/journal.pgen.1005544)
• Ingason, A. et al. 2015. Expression analysis in a rat psychosis model identifies novel candidate genes validated in a large case?control sample of schizophrenia. Translational Psychiatry 5(10), article number: e656. (10.1038/tp.2015.151)
• Walter, K. et al. 2015. The UK10K project identifies rare variants in health and disease. Nature 526, pp. 82-90. (10.1038/nature14962)
• Lee, S. H. et al. 2015. New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis. International Journal of Epidemiology 44(5), pp. 1706-1721. (10.1093/ije/dyv136)
• O'Donovan, M. C. 2015. What have we learned from the Psychiatric Genomics Consortium. World Psychiatry 14(3), pp. 291-293. (10.1002/wps.20270)
• Vilhjálmsson, B. et al. 2015. Modeling linkage disequilibrium increases accuracy of polygenic risk scores. American Journal of Human Genetics 97(4), pp. 576-592. (10.1016/j.ajhg.2015.09.001)
• Huang, J. et al. 2015. Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel. Nature Communications 6, article number: 8111. (10.1038/ncomms9111)
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• Martin, J., Hamshere, M. L., Stergiakouli, E., O'Donovan, M. C. and Thapar, A. 2015. Neurocognitive abilities in the general population and composite genetic risk scores for attention-deficit hyperactivity disorder. Journal of Child Psychology and Psychiatry 56(6), pp. 648-656. (10.1111/jcpp.12336)
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• Green, E. K. et al. 2015. Copy number variation in bipolar disorder. Molecular Psychiatry 21(1), pp. 89-93. (10.1038/mp.2014.174)
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2014

• Georgieva, L. et al. 2014. De novo CNVs in bipolar affective disorder and schizophrenia. Human Molecular Genetics 23(24), pp. 6677-6683. (10.1093/hmg/ddu379)
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• Crawford, A. A. et al. 2014. Adverse effects from antidepressant treatment: randomised controlled trial of 601 depressed individuals. Psychopharmacology 231(15), pp. 2921-2931. (10.1007/s00213-014-3467-8)
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• Craddock, N. J. et al. 2014. Identifying gene-environment interactions in schizophrenia: contemporary challenges for integrated, large-scale investigations. Schizophrenia Bulletin 40(4), pp. 729-736. (10.1093/schbul/sbu069)
• Morris, D. W. et al. 2014. An inherited duplication at the gene p21 Protein-Activated Kinase 7 (PAK7) is a risk factor for psychosis. Human Molecular Genetics 23(12), pp. 3316-3326. (10.1093/hmg/ddu025)
• Escott-Price, V. et al. 2014. Gene-wide analysis detects two new susceptibility genes for Alzheimer's Disease. PLoS ONE 9(6), article number: e94661. (10.1371/journal.pone.0094661)
• Liu, G. et al. 2014. Cardiovascular disease contributes to Alzheimer's disease: evidence from large-scale genome-wide association studies. Neurobiology of Aging 35(4), pp. 786-92. (10.1016/j.neurobiolaging.2013.10.084)
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• Rees, E. et al. 2014. CNV analysis in a large schizophrenia sample implicates deletions at 16p12.1 and SLC1A1 and duplications at 1p36.33 and CGNL1. Human Molecular Genetics 23(6), pp. 1669-1676. (10.1093/hmg/ddt540)
• Mulle, J. G. et al. 2014. Reciprocal duplication of the Williams-Beuren Syndrome deletion on chromosome 7q11.23 is associated with schizophrenia. Biological Psychiatry 75(5), pp. 371-7. (10.1016/j.biopsych.2013.05.040)
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• Fromer, M. et al. 2014. De novo mutations in schizophrenia implicate synaptic networks. Nature 506, pp. 179-184. (10.1038/nature12929)
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• Andreassen, O. A. et al. 2014. Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci. Molecular Psychiatry 20(2), pp. 207. (10.1038/mp.2013.195)
• Tansey, K. et al. 2014. Genetic susceptibility for bipolar disorder and response to antidepressants in major depressive disorder. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 165(1), pp. 77-83. (10.1002/ajmg.b.32210)
• Martin, J., Hamshere, M. L., O'Donovan, M. C., Rutter, M. and Thapar, A. 2014. Factor structure of autistic traits in children with ADHD. Journal of Autism and Developmental Disorders 44(1), pp. 204-215. (10.1007/s10803-013-1865-0)
• Hodgson, K. et al. 2014. Genetic predictors of antidepressant side effects: A grouped candidate gene approach in the Genome-Based Therapeutic Drugs for Depression (GENDEP) study. Journal of Psychopharmacology 28(2), pp. 142-150. (10.1177/0269881113517957)
• Bacanu, S. et al. 2014. Functional SNPs are enriched for schizophrenia association signals [Letter]. Molecular Psychiatry 19(3), pp. 276-277. (10.1038/mp.2013.33)

2013

• Green, E. K. et al. 2013. Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample. Molecular Psychiatry 18(12), pp. 1302-1307. (10.1038/mp.2012.142)
• van Scheltinga, A. F. T. et al. 2013. Schizophrenia genetic variants are not associated with intelligence. Psychological Medicine 43(12), pp. 2563-2570. (10.1017/S0033291713000196)
• Grozeva, D. et al. 2013. Reduced burden of very large and rare CNVs in bipolar affective disorder. Bipolar Disorders 15(8), pp. 893-8. (10.1111/bdi.12125)
• Lambert, J. et al. 2013. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease [Letter]. Nature Genetics 45(12), pp. 1452-1458. (10.1038/ng.2802)
• Rees, E. et al. 2013. Evidence that duplications of 22q11.2 protect against schizophrenia. Molecular Psychiatry n/a (10.1038/mp.2013.156)
• Zammit, S. et al. 2013. A population-based study of genetic variation and psychotic experiences in adolescents. Schizophrenia Bulletin 40(6), pp. 1254-1262. (10.1093/schbul/sbt146)
• de Candia, T. et al. 2013. Additive genetic variation in schizophrenia risk is shared by populations of African and European descent. American Journal of Human Genetics 93(3), pp. 463-470. (10.1016/j.ajhg.2013.07.007)
• Ruderfer, D. et al. 2013. Mosaic copy number variation in schizophrenia. European Journal of Human Genetics 21(9), pp. 1007-1011. (10.1038/ejhg.2012.287)
• Lee, S. et al. 2013. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nature Genetics 45(9), pp. 984-994. (10.1038/ng.2711)
• Ripke, S. et al. 2013. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nature Genetics 45(10), pp. 1150-1159. (10.1038/ng.2742)
• Walters, J. T. R. et al. 2013. The role of the major histocompatibility complex region in cognition and brain structure: a schizophrenia GWAS follow-up. American Journal of Psychiatry 170(8), pp. 877-885. (10.1176/appi.ajp.2013.12020226)
• Hamshere, M. L. et al. 2013. Shared polygenic contribution between childhood attention-deficit hyperactivity disorder and adult schizophrenia. British Journal of Psychiatry 203(2), pp. 107-111. (10.1192/bjp.bp.112.117432)
• Hamshere, M. L. et al. 2013. High loading of polygenic risk for ADHD in children with comorbid aggression. American Journal of Psychiatry 170(8), pp. 909-916. (10.1176/appi.ajp.2013.12081129)
• Majounie, E. et al. 2013. Variation in tau isoform expression in different brain regions and disease states. Neurobiology of Aging 34(7), pp. 1922.e7-1922.e12. (10.1016/j.neurobiolaging.2013.01.017)
• Yang, L. et al. 2013. Polygenic transmission and complex neuro developmental network for attention deficit hyperactivity disorder: Genome-wide association study of both common and rare variants. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 162(5), pp. 419-430. (10.1002/ajmg.b.32169)
• Hamshere, M. L. et al. 2013. Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC. Molecular Psychiatry 18(6), pp. 708-712. (10.1038/mp.2012.67)
• Landerl, K. et al. 2013. Predictors of developmental dyslexia in European orthographies with varying complexity. Journal of Child Psychology and Psychiatry 54(6), pp. 686-694. (10.1111/jcpp.12029)
• Zou, F. et al. 2013. Linking protective GAB2 variants, increased cortical GAB2 expression and decreased Alzheimer's Disease pathology. PLoS ONE 8(5), article number: e64802. (10.1371/journal.pone.0064802)
• Kavanagh, D., Dwyer, S., O'Donovan, M. C. and Owen, M. J. 2013. The ENCODE project: implications for psychiatric genetics. Molecular Psychiatry 18(5), pp. 540-542. (10.1038/mp.2013.13)
• Smoller, J. W. et al. 2013. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. The Lancet 381(9875), pp. 1371-1379. (10.1016/S0140-6736(12)62129-1)
• Lambert, J. C. et al. 2013. Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease [Correction]. Molecular Psychiatry 18(4), pp. 521. (10.1038/mp.2012.75)
• Kronenberg, F. et al. 2013. Novel Loci Associated with Increased Risk of Sudden Cardiac Death in the Context of Coronary Artery Disease [Article]. PLoS ONE 8(4), pp. e59905. (10.1371/journal.pone.0059905)
• Ripke, S. et al. 2013. A mega-analysis of genome-wide association studies for major depressive disorder. Molecular Psychiatry 18(4), pp. 497-511. (10.1038/mp.2012.21)
• Gibson, G. et al. 2013. All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs. PLoS Genetics 9(4), article number: e1003449. (10.1371/journal.pgen.1003449)
• Terwisscha van Scheltinga, A. F. et al. 2013. Genetic schizophrenia risk variants jointly modulate total brain and white matter volume. Biological Psychiatry 73(6), pp. 525-531. (10.1016/j.biopsych.2012.08.017)
• Guha, S. et al. 2013. Implication of a rare deletion at distal 16p11.2 in schizophrenia. JAMA Psychiatry 70(3), pp. 253-260. (10.1001/2013.jamapsychiatry.71)
• Williams, H. J., Monks, S., Murphy, K. C., Kirov, G., O'Donovan, M. C. and Owen, M. J. 2013. Schizophrenia two-hit hypothesis in velo-cardio facial syndrome. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 162(2), pp. 177-182. (10.1002/ajmg.b.32129)
• Donohoe, G. et al. 2013. Neuropsychological effects of the CSMD1 genome-wide associated schizophrenia risk variant rs10503253. Genes, Brain and Behavior 12(2), pp. 203-209. (10.1111/gbb.12016)
• Chapman, J. et al. 2013. A genome-wide study shows a limited contribution of rare copy number variants to Alzheimer's disease risk. Human Molecular Genetics 22(4), pp. 816-824. (10.1093/hmg/dds476)
• Andreassen, O. et al. 2013. Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors. American Journal of Human Genetics 92(2), pp. 197-209. (10.1016/j.ajhg.2013.01.001)
• Kim, Y. et al. 2013. Non-random mating, parent-of-origin, and maternal-fetal incompatibility effects in schizophrenia. Schizophrenia Research 143(1), pp. 11-17. (10.1016/j.schres.2012.11.002)
• Green, E. K. et al. 2013. Association at SYNE1 in both bipolar disorder and recurrent major depression. Molecular Psychiatry 18, pp. 614-617. (10.1038/mp.2012.48)
• Prata, D. P. et al. 2013. Risk variant of oligodendrocyte lineage transcription factor 2 is associated with reduced white matter integrity. Human Brain Mapping 34(9), pp. 2025-2031. (10.1002/hbm.22045)
• Kirov, G. et al. 2013. The penetrance of copy number variations for schizophrenia and developmental delay. Biological Psychiatry 75(5), pp. 378-385. (10.1016/j.biopsych.2013.07.022)
• Aberg, K. A. et al. 2013. A comprehensive family-based replication study of schizophrenia genes. JAMA Psychiatry 70(6), pp. 573-581. (10.1001/jamapsychiatry.2013.288)
• Visscher, P. M. et al. 2013. Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate. PLoS Genetics 9(4), pp. e1003455. (10.1371/journal.pgen.1003455)
• Chapuis, J. et al. 2013. Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology [Article]. Molecular Psychiatry 18(11), pp. 1225-1234. (10.1038/mp.2013.1)

2012

• Hollingworth, P. et al. 2012. Genome-wide association study of Alzheimer's disease with psychotic symptoms. Molecular Psychiatry 17(12), pp. 1316-1327. (10.1038/mp.2011.125)
• Eyre, S. et al. 2012. High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. Nature Genetics 44(12), pp. 1336-1340. (10.1038/ng.2462)
• Cooper, J. D. et al. 2012. Seven newly identified loci for autoimmune thyroid disease. Human Molecular Genetics 21(23), pp. 5202-5208. (10.1093/hmg/dds357)
• Jostins, L. et al. 2012. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature 491(7422), pp. 119-124. (10.1038/nature11582)
• Williams, H. J., Georgieva, L., Dwyer, S. L., Kirov, G., Owen, M. J. and O'Donovan, M. C. 2012. Absence of de novo point mutations in exons of GRIN2B in a large schizophrenia trio sample [Letter]. Schizophrenia Research 141(2-3), pp. 274-276. (10.1016/j.schres.2012.08.024)
• O'Donovan, M. C., Owen, M. J., Walters, J. T. R., Irish Schizophrenia Genomics Consortium, . and Wellcome Trust Case Control Consortium 2, . 2012. Genome-wide association study implicates HLA-C*01:02 as a risk factor at the major histocompatibility complex locus in schizophrenia. Biological psychiatry 72(8), pp. 620-628. (10.1016/j.biopsych.2012.05.035)
• Fromer, M. et al. 2012. Discovery and statistical genotyping of copy-number variation from whole-exome sequencing depth. American Journal of Human Genetics 91(4), pp. 597-607. (10.1016/j.ajhg.2012.08.005)
• Tansey, K. E. et al. 2012. Genetic predictors of response to serotonergic and noradrenergic antidepressants in major depressive disorder: a genome-wide analysis of individual-level data and a meta-analysis. Plos Medicine 9(10), article number: e1001326. (10.1371/journal.pmed.1001326)
• Levinson, D. F. et al. 2012. Genome-wide association study of multiplex schizophrenia pedigrees. American Journal of Psychiatry 169(9), pp. 963-973. (10.1176/appi.ajp.2012.11091423)
• Hamilton, G. et al. 2012. The role of ECE1 variants in cognitive ability in old age and Alzheimer's disease risk. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 159B(6), pp. 696-709. (10.1002/ajmg.b.32073)
• Ayalew, M. et al. 2012. Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction. Molecular Psychiatry 17(9), pp. 887-905. (10.1038/mp.2012.37)
• Shi, H. et al. 2012. Genetic variants influencing human aging from late-onset Alzheimer's disease (LOAD) genome-wide association studies (GWAS). Neurobiology of Aging 33(8), article number: 1849.e5. (10.1016/j.neurobiolaging.2012.02.014)
• Hamilton, G. et al. 2012. Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus. Neurobiology of Aging 33(8), article number: 1848.e1. (10.1016/j.neurobiolaging.2012.02.005)
• Escott-Price, V., Schmidt, K. M., Vedernikov, A., Owen, M. J., Craddock, N. J., Holmans, P. A. and O'Donovan, M. C. 2012. Permutation-based approaches do not adequately allow for linkage disequilibrium in gene-wide multi-locus association analysis. European Journal of Human Genetics 20(8), pp. 890-896. (10.1038/ejhg.2012.8)
• Sullivan, P. F., Daly, M. J. and O'Donovan, M. C. 2012. Genetic architectures of psychiatric disorders: the emerging picture and its implications. Nature Reviews Genetics 13(8), pp. 537-551. (10.1038/nrg3240)
• Jia, P. et al. 2012. Network-assisted investigation of combined causal signals from genome-wide association studies in schizophrenia. PLoS Computational Biology 8(7), article number: e1002587. (10.1371/journal.pcbi.1002587)
• Derks, E. M. et al. 2012. Investigation of the genetic association between quantitative measures of psychosis and schizophrenia: A polygenic risk score analysis. PLoS ONE 7(6), article number: e37852. (10.1371/journal.pone.0037852)
• Rees, E., Kirov, G., O'Donovan, M. C. and Owen, M. J. 2012. De Novo mutation in schizophrenia. Schizophrenia Bulletin 38(3), pp. 377-381. (10.1093/schbul/sbs047)
• Hudson, G. et al. 2012. No consistent evidence for association between mtDNA variants and Alzheimer disease. Neurology 78(14), pp. 1038-1042. (10.1212/WNL.0b013e31824e8f1d)
• Keller, M. C. et al. 2012. Runs of homozygosity implicate autozygosity as a schizophrenia risk factor. Plos Genetics 8(4), article number: e1002656. (10.1371/journal.pgen.1002656)
• Håvik, B. et al. 2012. DCLK1 variants are associated across schizophrenia and attention deficit/hyperactivity disorder. PLoS ONE 7(4), pp. e35424. (10.1371/journal.pone.0035424)
• Grozeva, D. et al. 2012. Independent estimation of the frequency of rare CNVs in the UK population confirms their role in schizophrenia. Schizophrenia Research 135(1-3), pp. 1-7. (10.1016/j.schres.2011.11.004)
• Lambert, J. C. et al. 2012. Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease. Molecular Psychiatry 18, pp. 461-470. (10.1038/mp.2012.14)
• Collins, A. L., Kim, Y., Sklar, P., O'Donovan, M. C. and Sullivan, P. F. 2012. Hypothesis-driven candidate genes for schizophrenia compared to genome-wide association results. Psychological Medicine 42(3), pp. 607-616. (10.1017/S0033291711001607)
• Kirov, G. et al. 2012. De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia. Molecular Psychiatry 17(2), pp. 142-153. (10.1038/mp.2011.154)
• Jia, P. et al. 2012. A bias-reducing pathway enrichment analysis of genome-wide association data confirmed association of the MHC region with schizophrenia. Journal of Medical Genetics 49(2), pp. 96-103. (10.1136/jmedgenet-2011-100397)
• Richards, A. et al. 2012. Schizophrenia susceptibility alleles are enriched for alleles that affect gene expression in adult human brain. Molecular Psychiatry 17(2), pp. 193-201. (10.1038/mp.2011.11)
• Stergiakouli, E. et al. 2012. Investigating the contribution of common genetic variants to the risk and pathogenesis of ADHD. American Journal of Psychiatry 169(2), pp. 186-194. (10.1176/appi.ajp.2011.11040551)
• Williams, N. M. et al. 2012. Genome-wide analysis of copy number variants in attention deficit hyperactivity disorder: the role of rare variants and duplications at 15q13.3. American Journal of Psychiatry 169(2), pp. 195-204. (10.1176/appi.ajp.2011.11060822)
• Gerrish, A. et al. 2012. The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's Disease. Journal of Alzheimer's Disease 28(2), pp. 377-387. (10.3233/JAD-2011-110824)
• Sullivan, P., Craddock, N. J., O'Donovan, M. C. and Owen, M. J. 2012. Don't give up on GWAS [Letter]. Molecular Psychiatry 17(1), pp. 2-3. (10.1038/mp.2011.94)
• Doherty, J. L., O'Donovan, M. C. and Owen, M. J. 2012. Recent genomic advances in schizophrenia. Clinical Genetics 81(2), pp. 103-109. (10.1111/j.1399-0004.2011.01773.x)
• Chapman, R. M., Tinsley, C. L., Doyle, A. M., O'Donovan, M. C. and Blake, D. J. 2012. Inducible over-expression and siRNA mediated knock-down of the schizophrenia susceptibility gene ZNF804A: Detection of altered gene expression and splicing using whole genome exon arrays. International Journal of Developmental Neuroscience 30(8), pp. 673-673. (10.1016/j.ijdevneu.2012.10.011)

2011

• Hinney, A. et al. 2011. Genome-wide association study in German patients with attention deficit/hyperactivity disorder. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 156(8), pp. 888-897. (10.1002/ajmg.b.31246)
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• Rees, E., Escott-Price, V., Owen, M. J., O'Donovan, M. C. and Kirov, G. 2011. De novo rates and selection of schizophrenia-associated copy number variants. Biological Psychiatry 70(12), pp. 1109-1114. (10.1016/j.biopsych.2011.07.011)
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• Ingason, A. et al. 2011. Maternally derived microduplications at 15q11-q13: Implication of imprinted genes in psychotic illness. American Journal of Psychiatry 168(4), pp. 408-417. (10.1176/appi.ajp.2010.09111660)
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• Zuliani, R. et al. 2011. Genetic variants in the ErbB4 gene are associated with white matter integrity. Psychiatry Research: Neuroimaging 191(2), pp. 133-137. (10.1016/j.pscychresns.2010.11.001)
• Reilly, M. P. et al. 2011. Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies. The Lancet 377(9763), pp. 383-392. (10.1016/S0140-6736(10)61996-4)
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• Williams, H. J., Escott-Price, V., Smith, R. L., Dwyer, S. L., Russo, G., Owen, M. J. and O'Donovan, M. C. 2011. Association between TCF4 and schizophrenia does not exert its effect by common nonsynonymous variation or by influencing cis-acting regulation of mRNA expression in adult human brain. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 156(7), pp. 781-784. (10.1002/ajmg.b.31219)
• Carroll, L. S., Williams, H. J., Walters, J. T. R., Kirov, G., O'Donovan, M. C. and Owen, M. J. 2011. Mutation screening of the 3q29 microdeletion syndrome candidate genes DLG1 and PAK2 in schizophrenia. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 156(7), pp. 844-849. (10.1002/ajmg.b.31231)
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• Escott-Price, V., O'Dushlaine, C., Purcell, S., Craddock, N. J., Holmans, P. A. and O'Donovan, M. C. 2011. Evaluation of an approximation method for assessment of overall significance of multiple-dependent tests in a genomewide association study. Genetic Epidemiology 35(8), pp. 861-866. (10.1002/gepi.20636)
• Cichon, S. et al. 2011. Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder. American Journal of Human Genetics 88(3), pp. 372-381. (10.1016/j.ajhg.2011.01.017)
• Hansen, T. et al. 2011. At-risk variant in TCF7L2 for type II diabetes increases risk of schizophrenia. Biological Psychiatry 70(1), pp. 59-63. (10.1016/j.biopsych.2011.01.031)
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• Langley, K. et al. 2011. Clinical and cognitive characteristics of children with attention-deficit hyperactivity disorder, with and without copy number variants. British Journal of Psychiatry 199(5), pp. 398-403.
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2010

• Langley, K., Heron, J., O'Donovan, M. C., Owen, M. J. and Thapar, A. 2010. Genotype link with extreme antisocial behavior: The contribution of cognitive pathways. Archives of General Psychiatry 67(12), pp. 1317-1323. (10.1001/archgenpsychiatry.2010.163)
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• Jones, L. et al. 2010. Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease. PLoS ONE 5(11), article number: e13950. (10.1371/journal.pone.0013950)
• Williams, N. M. et al. 2010. Rare chromosomal deletions and duplications in attention-deficit hyperactivity disorder: a genome-wide analysis. The Lancet 376(9750), pp. 1401-1408. (10.1016/S0140-6736(10)61109-9)
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• Allison, D. B. et al. 2010. Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function. PLoS Genetics 6(9), article number: e1001097. (10.1371/journal.pgen.1001097)
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• Ikeda, M. et al. 2010. Identification of novel candidate genes for treatment response to risperidone and susceptibility for schizophrenia: integrated analysis among pharmacogenomics, mouse expression, and genetic case-control association approaches. Biological psychiatry 67(3), pp. 263-269. (10.1016/j.biopsych.2009.08.030)
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• Owen, M. J., Craddock, N. J. and O'Donovan, M. C. 2010. Suggestion of roles for both common and rare risk variants in genome-wide studies of schizophrenia. Archives of General Psychiatry 67(7), pp. 667-673. (10.1001/archgenpsychiatry.2010.69)
• Ikeda, M. et al. 2010. Failure to confirm association between PIK4CA and psychosis in 22q11.2 deletion syndrome. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 153B(4), pp. 980-982. (10.1002/ajmg.b.31060)
• Green, E. K. et al. 2010. Variation at the GABAA receptor gene, Rho 1 (GABRR1) associated with susceptibility to bipolar schizoaffective disorder. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 153B(7), pp. 1347-1349. (10.1002/ajmg.b.31108)
• Dwyer, S. L., Williams, H., Holmans, P. A., Escott-Price, V., Craddock, N. J., Owen, M. J. and O'Donovan, M. C. 2010. No evidence that rare coding variants in ZNF804A confer risk of schizophrenia. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 153B(8), pp. 1411-1416. (10.1002/ajmg.b.31117)
• Talkowski, M. E. et al. 2010. Fine-mapping reveals novel alternative splicing of the dopamine transporter. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 153B(8), pp. 1434-1447. (10.1002/ajmg.b.31125)
• Neale, B. M. et al. 2010. Meta-analysis of genome-wide association studies of attention-deficit/hyperactivity disorder. Journal of the American Academy of Child & Adolescent Psychiatry 49(9), pp. 884-897. (10.1016/j.jaac.2010.06.008)
• Blake, D. J., Forrest, M., Chapman, R. M., Tinsley, C. L., O'Donovan, M. C. and Owen, M. J. 2010. TCF4, Schizophrenia, and Pitt-Hopkins Syndrome. Schizophrenia Bulletin 36(3), pp. 443-447. (10.1093/schbul/sbq035)
• Liu, Y. et al. 2010. Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder [Letter]. Molecular Psychiatry 16(1), pp. 2-4. (10.1038/mp.2009.107)
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2009

• Fowler, T. A. et al. 2009. Psychopathy trait scores in adolescents with childhood ADHD: the contribution of genotypes affecting MAOA, 5HTT and COMT activity. Psychiatric Genetics 19(6), pp. 312-319. (10.1097/YPG.0b013e3283328df4)
• Hayesmoore, J. B. G., Bray, N. J., Cross, W. C., Owen, M. J., O'Donovan, M. C. and Morris, H. R. 2009. The effect of age and the H1c MAPT haplotype on MAPT expression in human brain. Neurobiology of Aging 30(10), pp. 1652-1656. (10.1016/j.neurobiolaging.2007.12.017)
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• Harold, D. et al. 2009. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease [Letter]. Nature Genetics 41(10), pp. 1088-1093. (10.1038/ng.440)
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• Holmans, P. A. et al. 2009. Genomewide linkage scan of schizophrenia in a large multicenter pedigree sample using single nucleotide polymorphisms. Molecular Psychiatry 14(8), pp. 786-795. (10.1038/mp.2009.11)
• Orozco, G. et al. 2009. Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23. Human Molecular Genetics 18(14), pp. 2693-2699. (10.1093/hmg/ddp193)
• Holmans, P. A. et al. 2009. Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder. American Journal of Human Genetics 85(1), pp. 13-24. (10.1016/j.ajhg.2009.05.011)
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• Raychaudhuri, S. et al. 2009. Identifying relationships among genomic disease regions: Predicting genes at pathogenic SNP associations and rare deletions. Plos Genetics 5(6), pp. -. (10.1371/journal.pgen.1000534)
• Kirov, G. et al. 2009. Support for the involvement of large copy number variants in the pathogenesis of schizophrenia. Human Molecular Genetics 18(8), pp. 1497-1503. (10.1093/hmg/ddp043)
• Escott-Price, V. et al. 2009. Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk. Molecular Psychiatry 14(3), pp. 252-260. (10.1038/mp.2008.133)
• O'Donovan, M. C. et al. 2009. Analysis of 10 independent samples provides evidence for association between schizophrenia and a SNP flanking fibroblast growth factor receptor 2. Molecular Psychiatry 14(1), pp. 30-36. (10.1038/mp.2008.108)
• Hamshere, M. L. et al. 2009. Genetic utility of broadly defined bipolar schizoaffective disorder as a diagnostic concept. British Journal of Psychiatry 195(1), pp. 23-29. (10.1192/bjp.bp.108.061424)
• Harold, D. et al. 2009. Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease [Corrigendum]. Nature Genetics 41(10), pp. 1156. (10.1038/ng1009-1156d)
• Purcell, S. M. et al. 2009. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 460(7256), pp. 748-752. (10.1038/nature08185)
• Williams, H., Owen, M. J. and O'Donovan, M. C. 2009. Schizophrenia genetics: new insights from new approaches. British Medical Bulletin 91(1), pp. 61-74. (10.1093/bmb/ldp017)
• O'Donovan, M. C., Craddock, N. J. and Owen, M. J. 2009. Strong evidence for multiple psychosis susceptibility genes - a rejoinder to Crow [Letter]. Psychological Medicine 39(1), pp. 170-171. (10.1017/S0033291708004583)
• Langley, K. et al. 2009. Molecular genetic contribution to the developmental course of attention-deficit hyperactivity disorder. European Child & Adolescent Psychiatry 18(1), pp. 26-32. (10.1007/s00787-008-0698-4)
• Morgan, A. R. et al. 2009. Association analysis of dynamin-binding protein (DNMBP) on chromosome 10q with late onset Alzheimer's disease in a large caucasian UK sample. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 150B(1), pp. 61-64. (10.1002/ajmg.b.30768)
• Talkowski, M. E. et al. 2009. Convergent patterns of association between phenylalanine hydroxylase variants and schizophrenia in four independent samples. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 150B(4), pp. 560-569. (10.1002/ajmg.b.30862)
• Carroll, L. S., Kendall, K., O'Donovan, M. C., Owen, M. J. and Williams, N. M. 2009. Evidence that putative ADHD low risk alleles atSNAP25may increase the risk of schizophrenia. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 150B(7), pp. 893-899. (10.1002/ajmg.b.30915)
• Green, E. K. et al. 2009. P2RX7: A bipolar and unipolar disorder candidate susceptibility gene?. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 150B(8), pp. 1063-1069. (10.1002/ajmg.b.30931)
• Abraham, R. A., Sims, R., Carroll, L. S., Hollingworth, P., O'Donovan, M. C., Williams, J. and Owen, M. J. 2009. An association study of common variation at theMAPTlocus with late-onset Alzheimer's disease. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 150B(8), pp. 1152-1155. (10.1002/ajmg.b.30951)
• Dwyer, S. L., Carroll, L. S., Mantripragada, K. K., Owen, M. J., O'Donovan, M. C. and Williams, N. M. 2009. Mutation screening of the DTNBP1 exonic sequence in 669 schizophrenics and 710 controls using high-resolution melting analysis. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 153B(3), pp. 766-774. (10.1002/ajmg.b.31045)
• O'Donovan, M. C. and Owen, M. J. 2009. Genetics and the brain: many pathways to enlightenment [Editorial]. Human Genetics 126(1), pp. 1-2. (10.1007/s00439-009-0705-y)
• Owen, M. J., Williams, H. J. and O'Donovan, M. C. 2009. Schizophrenia genetics: advancing on two fronts. Current Opinion in Genetics & Development 19(3), pp. 266-270. (10.1016/j.gde.2009.02.008)
• Gerrish, A., Williams, H. J., Escott-Price, V., Owen, M. J., O'Donovan, M. C. and Williams, N. M. 2009. An examination of MUTED as a schizophrenia susceptibility gene [Letter]. Schizophrenia Research 107(1), pp. 110-111. (10.1016/j.schres.2008.08.011)
• Sims, R. et al. 2009. Evidence that variation in the oligodendrocyte lineage transcription factor 2 (OLIG2) gene is associated with psychosis in Alzheimer's disease. Neuroscience Letters 461(1), pp. 54-59. (10.1016/j.neulet.2009.05.051)
• Yosifova, A. et al. 2009. Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population. Journal of Affective Disorders 117(1-2), pp. 87-97. (10.1016/j.jad.2008.12.021)
• Ingason, A. et al. 2009. A large replication study and meta-analysis in European samples provides further support for association of AHI1 markers with schizophrenia. Human Molecular Genetics 19(7), pp. 1379-1386. (10.1093/hmg/ddq009)
• Craddock, N. J., O'Donovan, M. C. and Owen, M. J. 2009. Psychosis genetics: modeling the relationship between Schizophrenia, Bipolar Disorder, and Mixed (or "Schizoaffective") Psychoses. Schizophrenia Bulletin 35(3), pp. 482-490. (10.1093/schbul/sbp020)
• Kirov, G., Rujescu, D., Ingason, A., Collier, D. A., O'Donovan, M. C. and Owen, M. J. 2009. Neurexin 1 (NRXN1) deletions in Schizophrenia. Schizophrenia Bulletin 35(5), pp. 851-854. (10.1093/schbul/sbp079)
• Fowler, T. A. et al. 2009. Psychopathy traits in adolescents with childhood attention-deficit hyperactivity disorder. British Journal of Psychiatry 194(1), pp. 62-67. (10.1192/bjp.bp.107.046870)
• Williams, H. J., Owen, M. J. and O'Donovan, M. C. 2009. New findings from genetic association studies of schizophrenia. Journal of Human Genetics 54(1), pp. 9-14. (10.1038/jhg.2008.7)
• Betcheva, E. T. et al. 2009. Case-control association study of 59 candidate genes reveals the DRD2 SNP rs6277 (C957T) as the only susceptibility factor for schizophrenia in the Bulgarian population. Journal of Human Genetics 54(2), pp. 98-107. (10.1038/jhg.2008.14)

2008

• Barton, A. et al. 2008. Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13. Nature Genetics 40(10), pp. 1156-1159. (10.1038/ng.218)
• Hayesmoore, J. B., Bray, N. J., Owen, M. J. and O'Donovan, M. C. 2008. DISC1mRNA expression is not influenced by common Cis-acting regulatory polymorphisms or imprinting.. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 147B(7), pp. 1065-1069. (10.1002/ajmg.b.30715)
• Ikeda, M. et al. 2008. Variants of dopamine and serotonin candidate genes as predictors of response to risperidone treatment in first-episode schizophrenia. Pharmacogenomics 9(10), pp. 1437-1443. (10.2217/14622416.9.10.1437)
• Craddock, N. J. et al. 2008. Wake up call: Response from authors [eLetter]. British Journal of Psychiatry
• Abraham, R. et al. 2008. A genome-wide association study for late-onset Alzheimer's disease using DNA pooling. BMC Medical Genomics 1(1), article number: 44. (10.1186/1755-8794-1-44)
• Ferreira, M. A. R. et al. 2008. Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nature Genetics 40(9), pp. 1056-1058. (10.1038/ng.209)
• Georgieva, L. et al. 2008. Support for Neuregulin 1 as a susceptibility gene for Bipolar disorder and schizophrenia. Biological psychiatry 64(5), pp. 419-427. (10.1016/j.biopsych.2008.03.025)
• Barton, A. et al. 2008. Re-evaluation of putative rheumatoid arthritis susceptibility genes in the post-genome wide association study era and hypothesis of a key pathway underlying susceptibility. Human Molecular Genetics 17(15), pp. 2274-2279. (10.1093/hmg/ddn128)
• Loos, R. J. F. et al. 2008. Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nature Genetics 40(6), pp. 768-775. (10.1038/ng.140)
• Fisher, S. A. et al. 2008. Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease. Nature Genetics 40(6), pp. 710-712. (10.1038/ng.145)
• Thomas, L. et al. 2008. GENetic and clinical predictors of treatment response in depression: the GenPod randomised trial protocol. Trials 9(1), pp. 29-29. (10.1186/1745-6215-9-29)
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2007

• Nejentsev, S. et al. 2007. Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A. Nature 450(7171), pp. 887-892. (10.1038/nature06406)
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• Craddock, N. J., O'Donovan, M. C. and Owen, M. J. 2007. Phenotypic and genetic complexity of psychosis Invited commentary on .. Schizophrenia: a common disease caused by multiple rare alleles. British Journal of Psychiatry 190(3), pp. 200-203. (10.1192/bjp.bp.106.033761)

2006

• Harold, D. et al. 2006. Further evidence that the KIAA0319 gene confers susceptibility to developmental dyslexia. Molecular Psychiatry 11(12), pp. 1085-91. (10.1038/sj.mp.4001904)
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• Kirov, G., Nikolov, I., Georgieva, L., Escott-Price, V., Owen, M. J. and O'Donovan, M. C. 2006. Pooled DNA genotyping on Affymetrix SNP genotyping arrays. BMC Genomics 7(1), pp. 27-37. (10.1186/1471-2164-7-27)
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• Grupe, A. et al. 2006. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. The American Journal of Human Genetics 78(1), pp. 78-88.
• Peirce, T. R. et al. 2006. Convergent evidence for 2',3'-cyclic nucleotide 3'-phosphodiesterase as a possible susceptibility gene for schizophrenia. Archives of general psychiatry 63(1), pp. 18-24. (10.1001/archpsyc.63.1.18)
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• Craddock, N. J., Owen, M. J. and O'Donovan, M. C. 2006. The catechol-O-methyl transferase (COMT) gene as a candidate for psychiatric phenotypes: evidence and lessons. Molecular Psychiatry 11(5), pp. 446-458. (10.1038/sj.mp.4001808)
• Green, E. K. et al. 2006. Genetic variation of brain-derived neurotrophic factor (BDNF) in bipolar disorder: case-control study of over 3000 individuals from the UK. British Journal of Psychiatry 188(1), pp. 21-25. (10.1192/bjp.bp.105.009969)

2005

• Langley, K. et al. 2005. No support for association between the dopamine transporter (DAT1) gene and ADHD. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 139B(1), pp. 7-10. (10.1002/ajmg.b.30206)
• Thapar, A. et al. 2005. Catechol O-methyltransferase gene variant and birth weight predict early-onset antisocial behavior in children with attention-deficit/hyperactivity disorder. Archives of General Psychiatry 62(11), pp. 1275-1278. (10.1001/archpsyc.62.11.1275)
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• Thapar, A., O'Donovan, M. C. and Owen, M. J. 2005. The genetics of attention deficit hyperactivity disorder. Human Molecular Genetics 14(2), pp. 275-282. (10.1093/hmg/ddi263)
• Hamshere, M. L. et al. 2005. Genomewide linkage scan in schizoaffective disorder: significant evidence for linkage at 1q42 close to DISC1, and suggestive evidence at 22q11 and 19p13. Archives of general psychiatry 62(10), pp. 1081-1088. (10.1001/archpsyc.62.10.1081)
• Williams, N. M., O'Donovan, M. C. and Owen, M. J. 2005. Is the dysbindin gene (DTNBP1) a susceptibility gene for schizophrenia?. Schizophrenia Bulletin 31(4), pp. 800-805. (10.1093/schbul/sbi061)
• Buckland, P. R., Hoogendoorn, B., Coleman, S. L., Guy, C., Smith, S. K. and O'Donovan, M. C. 2005. Strong bias in the location of functional promoter polymorphisms. Human Mutation 26(3), pp. 214-223. (10.1002/humu.20207)
• Williams, H. J. et al. 2005. No association between schizophrenia and polymorphisms in COMT in two large samples. American Journal of Psychiatry 162(9), pp. 1736-1738. (10.1176/appi.ajp.162.9.1736)
• Redfern, A. et al. 2005. Global gene expression profiling in the hippocampus and frontal cortex of Escitalopram-treated Learned Helplessness rats. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 138B(1), pp. 107-107.
• Nowotny, P. et al. 2005. Association studies between risk for late-onset Alzheimer's disease and variants in insulin degrading enzyme. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 136B(1), pp. 62-68. (10.1002/ajmg.b.30186)
• Glaser, B. et al. 2005. No association between the putative functional ZDHHC8 single nucleotide polymorphism rs175174 and schizophrenia in large European samples. Biological psychiatry 58(1), pp. 78-80.
• Green, E. K. et al. 2005. Operation of the schizophrenia susceptibility gene, neuregulin 1, across traditional diagnostic boundaries to increase risk for bipolar disorder. Archives of general psychiatry 62(6), pp. 642-648. (10.1001/archpsyc.62.6.642)
• Kirov, G., O'Donovan, M. C. and Owen, M. J. 2005. Finding schizophrenia genes. The Journal of Clinical Investigation 115(6), pp. 1440-1448. (10.1172/JCI24759)
• Turic, D. et al. 2005. A family based study implicates solute carrier family 1-member 3 (SLC1A3) gene in attention-deficit/hyperactivity disorder. Biological psychiatry 57(11), pp. 1461-1466. (10.1016/j.biopsych.2005.03.025)
• O'Donovan, M. C. 2005. An evaluation of chromatin condensation and DNA integrity in the spermatozoa of men with cancer before and after therapy. Andrologia -Berlin- 37(2-3), pp. 83-90. (10.1111/j.1439-0272.2005.00658.x)
• Norton, N. et al. 2005. No evidence for association between polymorphisms in GRM3 and schizophrenia. BMC Psychiatry 5, article number: 23. (10.1186/1471-244X-5-23)
• Holmans, P. A. et al. 2005. Genome screen for loci influencing age at onset and rate of decline in late onset Alzheimer's disease. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 135B(1), pp. 24-32. (10.1002/ajmg.b.30114)
• Bray, N. J., Preece, A. C., Williams, N. M., Escott-Price, V., Buckland, P. R., Owen, M. J. and O'Donovan, M. C. 2005. Haplotypes at the dystrobrevin binding protein 1 (DTNBP1) gene locus mediate risk for schizophrenia through reduced DTNBP1 expression. Human Molecular Genetics 14(14), pp. 1947-1954. (10.1093/hmg/ddi199)
• Cope, N. A. et al. 2005. Strong evidence that KIAA0319 on chromosome 6p is a susceptibility gene for developmental dyslexia. American Journal of Human Genetics 76(4), pp. 581-591. (10.1086/429131)
• Escott-Price, V., Norton, N., Williams, N. M., Holmans, P. A., Owen, M. J. and O'Donovan, M. C. 2005. Streamlined analysis of pooled genotype data in SNP-based association studies. Genetic Epidemiology 28(3), pp. 273-282. (10.1002/gepi.20062)
• Buckland, P. R., Hoogendoorn, B., Guy, C., Smith, S. K., Coleman, S. L. and O'Donovan, M. C. 2005. Low gene expression conferred by association of an allele of the 5-HT2C receptor gene with antipsychotic-induced weight gain. American Journal of Psychiatry 162(3), pp. 613-615. (10.1176/appi.ajp.162.3.613)
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• Turic, D., Williams, H., Langley, K., Owen, M. J., Thapar, A. and O'Donovan, M. C. 2005. A family based study of catechol-O-methyltransferase (COMT) and attention deficit hyperactivity disorder (ADHD).. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 133B(1), pp. 64-67. (10.1002/ajmg.b.30123)
• Owen, M. J., O'Donovan, M. C. and Harrison, P. J. 2005. Schizophrenia: a genetic disorder of the synapse?. British Medical Journal (BMJ) 330(7484), pp. 158-159. (10.1136/bmj.330.7484.158)
• Craddock, N. J., O'Donovan, M. C. and Owen, M. J. 2005. Genes for schizophrenia and bipolar disorder? Implications for psychiatric nosology. Schizophrenia Bulletin 32(1), pp. 9-16. (10.1093/schbul/sbj033)
• Kent, L. et al. 2005. Association of the paternally transmitted copy of common Valine allele of the Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene with susceptibility to ADHD. Molecular Psychiatry 10(10), pp. 939-943. (10.1038/sj.mp.4001696)
• Glaser, B., Kirov, G., Bray, N. J., Green, E., O'Donovan, M. C., Craddock, N. J. and Owen, M. J. 2005. Identification of a potential Bipolar risk haplotype in the gene encoding the winged-helix transcription factor RFX4. Molecular Psychiatry 10(10), pp. 920-927. (10.1038/sj.mp.4001689)
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• Green, E. et al. 2005. Localization of bipolar susceptibility locus by molecular genetic analysis of the chromosome 12q23-q24 region in two pedigrees with bipolar disorder and Darier's disease. American Journal of Psychiatry 162(1), pp. 35-42. (10.1176/appi.ajp.162.1.35)

2004

• Buckland, P. R. et al. 2004. A high proportion of polymorphisms in the promoters of brain expressed genes influences transcriptional activity. Acta Biochimica et Biophysica 1690(3), pp. 238-249.
• Fowler, T. A. et al. 2004. Early onset antisocial behaviour in children with ADHD is associated with a functional variant in the catechol-O-methyltransferase (COMT) gene [Abstract]. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 130B(1), pp. 98-98. (10.1002/ajmg.b.30101)
• Bray, N. J. et al. 2004. Allelic variation in the expression of neuropsychiatric candidate genes [Conference Abstract]. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 130B(1), pp. 25-25.
• Peirce, T. R. et al. 2004. Convergent functional genomics, association and linkage analysis suggests 2 ',3 '-cyclic nucleotide 3 '-phosphodiesterase (CNP) as a potential susceptibility gene for schizophrenia [Conference Abstract]. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 130B(1), pp. 81-81. (10.1002/ajmg.b.30101)
• Bray, N. J., Jehu, L., Escott-Price, V., Buckland, P. R., Williams, J., Owen, M. J. and O'Donovan, M. C. 2004. Allelic expression of APOE in brain [Conference Abstract]. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 130B(1), pp. 61-61.
• Norton, N. et al. 2004. Interaction between neuregulin 1 and its receptor ERBB4 increases susceptibility to schizophrenia [Conference Abstract]. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 130B(1), pp. 18-18.
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• Morris, D. et al. 2004. Association analysis of two candidate phospholipase genes that map to the chromosome 15q15.1-15.3 region associated with reading disability. American Journal Of Medical Genetics Part A 129B(1), pp. 97-103. (10.1002/ajmg.b.30033)
• Hoogendoorn, B., Coleman, S. L., Guy, C., Smith, S. K., O'Donovan, M. C. and Buckland, P. R. 2004. Functional analysis of polymorphisms in the promoter regions of genes on 22q11. Human Mutation 24(1), pp. 35-42. (10.1002/humu.20061)
• Zammit, S. et al. 2004. Polymorphisms in the MAOA, MAOB, and COMT genes and aggressive behavior in schizophrenia. American Journal of Medical Genetics 128B(1), pp. 19-20. (10.1002/ajmg.b.30021)
• Bray, N. J., Jehu, L., Escott-Price, V., Buckland, P. R., Owen, M. J., Williams, J. and O'Donovan, M. C. 2004. P4-101 Allelic expression of APOE in brain [Conference Abstract]. Neurobiology of Aging 25, pp. S503-S503. (10.1016/S0197-4580(04)81659-2)
• Mills, S. et al. 2004. No evidence of association between Catechol-O-Methyltransferase (COMT) Val(158)Met genotype and performance on neuropsychological tasks in children with ADHD: A case-control study. BMC Psychiatry 4, pp. 15-15. (10.1186/1471-244X-4-15)
• Plomin, R. et al. 2004. A functional polymorphism in the succinate-semialdehyde dehydrogenase (aldehyde dehydrogenase 5 family, member A1) gene is associated with cognitive ability. Molecular Psychiatry 9(6), pp. 582-586. (10.1038/sj.mp.4001441)
• Kirov, G. et al. 2004. Strong evidence for association between the dystrobrevin binding protein 1 gene (DTNBP1) and schizophrenia in 488 parent-offspring trios from Bulgaria. Biological psychiatry 55(10), pp. 971-975. (10.1016/j.biopsych.2004.01.025)
• Turic, D., Langley, K., Kirov, G., Owen, M. J., Thapar, A. and O'Donovan, M. C. 2004. Direct analysis of the genes encoding G proteins G alpha T2, G alpha o, G alpha Z in ADHD. American Journal of Medical Genetics 127B(1), pp. 68-72. (10.1002/ajmg.b.20173)
• Owen, M. J., Williams, N. M. and O'Donovan, M. C. 2004. Dysbindin-1 and schizophrenia: from genetics to neuropathology. The Journal of Clinical Investigation 113(9), pp. 1255-1257. (10.1172/JCI200421470)
• Murphy, K., Williams, H., Owen, M. J. and O'Donovan, M. C. 2004. What can velo-cardio-facial syndrome tell us about the genetics of schizophrenia?. European Psychiatry 19(Supp1), pp. 96S-96S.
• Williams, N. M. et al. 2004. Identification in 2 independent samples of a novel schizophrenia risk haplotype of the dystrobrevin binding protein gene (DTNBP1). Archives of General Psychiatry 61(4), pp. 336-344. (10.1001/archpsyc.61.4.336)
• Huezo-Diaz, P. et al. 2004. An association study of the neurotensin receptor gene with schizophrenia and clozapine response. Schizophrenia Research 66(2-3), pp. 193-195. (10.1016/S0920-9964(03)00128-2)
• Williams, N. M. et al. 2004. Support for RGS4 as a susceptibility gene for schizophrenia. Biological Psychiatry 55(2), pp. 192-195. (10.1016/j.biopsych.2003.11.002)
• Langley, K., Marshall, L., van den Bree, M. B., Thomas, H. V., Owen, M. J., O'Donovan, M. C. and Thapar, A. 2004. Association of the dopamine D4 receptor gene 7-repeat allele with neuropsychological test performance of children with ADHD. American Journal of Psychiatry 161(1), pp. 133-138. (10.1176/appi.ajp.161.1.133)
• Williams, N. M. et al. 2004. Identification in two independent samples of a novel schizophrenia risk haplotype of the dystobrevin binding protein gene (DTNBP1). Archives of general psychiatry 61(4), pp. 336-344. (10.1001/archpsyc.61.4.336)
• Guy, C., Hoogendoorn, B., Smith, S. K., Coleman, S. L., O'Donovan, M. C. and Buckland, P. R. 2004. Promoter polymorphisms in glutathione-S-transferase genes affect transcription. Pharmacogenetics 14(1), pp. 45-51. (10.1097/00008571-200401000-00005)
• Owen, M. J., Williams, N. M. and O'Donovan, M. C. 2004. The molecular genetics of schizophrenia: new findings promise new insights. Molecular Psychiatry 9(1), pp. 14-27. (10.1038/sj.mp.4001444)
• Myers, A. J. et al. 2004. Variation in the urokinase-plasminogen activator gene does not explain the chromosome 10 linkage signal for late onset AD. American Journal of Medical Genetics 124B(1), pp. 29-37. (10.1002/ajmg.b.20036)
• Bray, N. J., Buckland, P. R., Hall, H., Owen, M. J. and O'Donovan, M. C. 2004. The serotonin-2A receptor gene locus does not contain common polymorphism affecting mRNA levels in adult brain. Molecular Psychiatry 9(1), pp. 109-114. (10.1038/sj.mp.4001366)
• Bray, N. J. et al. 2004. Allelic expression of APOE in human brain: effects of epsilon status and promoter haplotypes. Human Molecular Genetics 13(22), pp. 2885-2892. (10.1093/hmg/ddh299)
• Cichon, S. et al. 2004. Lack of support for a genetic association of the XBP1 promoter polymorphism with bipolar disorder in probands of European origin. Nature Genetics 36(8), pp. 783-784. (10.1038/ng0804-783)
• Turic, D. et al. 2004. Follow-up of genetic linkage findings on chromosome 16p13: evidence of association of N-methyl-D aspartate glutamate receptor 2A gene polymorphism with ADHD. Molecular Psychiatry 9(2), pp. 169-173. (10.1038/sj.mp.4001387)
• Norton, N., Williams, N. M., O'Donovan, M. C. and Owen, M. J. 2004. DNA pooling as a tool for large-scale association studies in complex traits. Annals of Medicine 36(2), pp. 146-152. (10.1080/07853890310021724)
• Busby, V. et al. 2004. Alpha-T-Catenin Is Expressed in Human Brain and Interacts With the Wnt Signaling Pathway But Is Not Responsible for Linkage to Chromosome 10 in Alzheimer's Disease. Neuromolecular Medicine 5(2), pp. 133-146. (10.1385/NMM:5:2:133)

2003

• Williams, N. M. et al. 2003. A systematic genomewide linkage study in 353 sib pairs with schizophrenia. The American journal of human genetics 73(6), pp. 1355-1367. (10.1086/380206)
• Smith, S. K., Hoogendoorn, B., Guy, C., Coleman, S. L., O'Donovan, M. C. and Buckland, P. R. 2003. Lack of functional promoter polymorphisms in genes involved in glutamate neurotransmission. Psychiatric Genetics 13(4), pp. 193-199. (10.1097/00041444-200312000-00001)
• Ivanov, D. et al. 2003. Chromosome 22q11 deletions, velo-cardio-facial syndrome and early-onset psychosis: Molecular genetic study. The British Journal of Psychiatry 183(5), pp. 409-413. (10.1192/bjp.183.5.409)
• Thapar, A., Langley, K., Marshall, L., van den Bree, M. B., Thomas, H. V., Owen, M. J. and O'Donovan, M. C. 2003. ADHD children with and without the dopamine D4 receptor 7-repeat allele: Evidence of differences in performance on neuropsychological tests. Behavior Genetics 33(6), pp. 721-721.
• O'Donovan, M. C., Williams, N. M. and Owen, M. J. 2003. Recent advances in the genetics of schizophrenia. Human Molecular Genetics 12(suppl), pp. R125-R133. (10.1093/hmg/ddg302)
• Kirov, G. et al. 2003. Variation in the protocadherin - A gene cluster?. Genomics 82(4), pp. 433-440. (10.1016/S0888-7543(03)00167-8)
• Hoogendoorn, B., Coleman, S. L., Guy, C., Smith, S. K., Bowen, T., Buckland, P. R. and O'Donovan, M. C. 2003. Functional analysis of human promoter polymorphisms. Human Molecular Genetics 12(18), pp. 2249-2254. (10.1093/hmg/ddg246)
• Payton, A. et al. 2003. No evidence of association between HLA-DRB1 and attention deficit hyperactivity disorder.. Psychiatric Genetics 13(3), pp. 183-185.
• Harold, D. et al. 2003. Sequence variation in the CHAT locus shows no association with late-onset Alzheimer's disease. Human Genetics 113(3), pp. 258-267. (10.1007/s00439-003-0960-2)
• Norton, N. et al. 2003. Mutation screening of the Homer gene family and association analysis in schizophrenia. American Journal of Medical Genetics 120B(1), pp. 18-21. (10.1002/ajmg.b.20032)
• Bray, N. J., Buckland, P. R., Williams, N. M., Williams, H. J., Norton, N., Owen, M. J. and O'Donovan, M. C. 2003. A haplotype implicated in schizophrenia susceptibility is associated with reduced COMT expression in human brain. The American Journal of Human Genetics 73(1), pp. 152-161. (10.1086/376578)
• Bray, N. B., Buckland, P. R., Owen, M. J. and O'Donovan, M. C. 2003. Cis-acting variation in the expression of a high proportion of genes in human brain. Human Genetics 113(2), pp. 149-153. (10.1007/s00439-003-0956-y)
• Williams, H. et al. 2003. Detailed analysis of PRODH and PsPRODH reveals no association with schizophrenia. American Journal of Medical Genetics 120B(1), pp. 42-46. (10.1002/ajmg.b.20049)
• Williams, H. J. et al. 2003. Association between PRODH and schizophrenia is not confirmed. Molecular Psychiatry 8(7), pp. 644-645. (10.1038/sj.mp.4001276)
• Lewis, C. M. et al. 2003. Genome scan meta-analysis of schizophrenia and bipolar disorder, Part II: schizophrenia. American Journal of Human Genetics 73(1), pp. 34-48. (10.1086/376549)
• Langley, K. et al. 2003. No evidence of association of two 5HT transporter gene polymorphisms and attention deficit hyperactivity disorder. Psychiatric Genetics 13(2), pp. 107-110. (10.1097/01.ypg.0000056177.32550.a5)
• Williams, N. M. et al. 2003. Support for genetic variation in neuregulin 1 and susceptibility to schizophrenia. Molecular Psychiatry 8(5), pp. 485-487. (10.1038/sj.mp.4001348)
• Turic, D. et al. 2003. Linkage disequilibrium mapping provides further evidence of a gene for reading disability on chromosome 6p21.3-22. Molecular Psychiatry 8(2), pp. 176-185. (10.1038/sj.mp.4001216)
• Lawson, D. C. et al. 2003. Association analysis of monoamine oxidase a and attention deficit hyperactivity disorder. American Journal of Medical Genetics 116B(1), pp. 84-89. (10.1002/ajmg.b.10002)
• O'Donovan, M. C. and Owen, M. J. 2003. Genetic findings in psychotic disorders. In: Soares, J. C. and Gershon, S. eds. Handbook of Medical Psychiatry. New York: Marcel Dekker, pp. 417-432.
• Owen, M. J. and O'Donovan, M. C. 2003. Schizophrenia and genetics. In: Plomin, R. et al. eds. Behavioral Genetics in the Postgenomic Era. Washington, DC: APA Books, pp. 463-480., (10.1037/10480-023)
• Buckland, P. R., Coleman, S. L., Hoogendoorn, B., Guy, C., Smith, S. K. and O'Donovan, M. C. 2003. A high proportion of chromosome 21 promoter polymorphisms influence transcriptional activity. Gene Expression 11(5), pp. 233-239. (10.3727/000000003783992225)
• O'Donovan, M. C., Jones, I. R. and Craddock, N. J. 2003. Anticipation and repeat expansion in bipolar disorder. American Journal of Medical Genetics 123C(1), pp. 10-17. (10.1002/ajmg.c.20009)

2002

• Sham, P., Bader, J. S., Craig, I., O'Donovan, M. C. and Owen, M. J. 2002. DNA Pooling: a tool for large-scale association studies. Nature Reviews Genetics 3(11), pp. 862-871. (10.1038/nrg930)
• Bray, N. J. et al. 2002. Screening the protocadherin 8 (PCDH8) gene in schizophrenia [Conference Abstract]. American Journal of Medical Genetics 114(7), pp. 844-844.
• Bray, N. J., Buckland, P. R., Williams, H., Norton, N., Williams, N. M., Owen, M. J. and O'Donovan, M. C. 2002. Detection of cis-acting polymorphisms and epigenetic modification affecting gene expression [Conference Abstracts]. American Journal of Medical Genetics 114(7), pp. 750-750. (10.1002/ajmg.10971)
• Bray, N. J. et al. 2002. Screening the human protocadherin 8 (PCDH8) gene in schizophrenia. Genes, Brain and Behavior 1(3), pp. 187-191. (10.1034/j.1601-183X.2002.10307.x)
• Coleman, S. L., Hoogendoorn, B., Guy, C., Smith, S. K., O'Donovan, M. C. and Buckland, P. R. 2002. Streamlined approach to functional analysis of promoter-region polymorphisms. Biotechniques 33(2), pp. 412-418.
• Norton, N. et al. 2002. Schizophrenia and functional polymorphisms in the MAOA and COMT genes: No evidence for association or epistasis. American Journal Of Medical Genetics Part A 114(5), pp. 491-496. (10.1002/ajmg.10517)
• Norton, N. et al. 2002. Universal, robust, highly quantitative SNP allele frequency measurement in DNA pools. Human Genetics 110(5), pp. 471-478. (10.1007/s00439-002-0706-6)
• Levinson, D. F. et al. 2002. No major schizophrenia locus detected on chromosome 1q in a large multicenter sample. Science 296(5568), pp. 739-741. (10.1126/science.1069914)
• Anney, R. et al. 2002. Characterisation, mutation detection, and association analysis of alternative promoters and 5' UTRs of the human dopamine D3 receptor gene in schizophrenia. Molecular psychiatry 7(5), pp. 493-502. (10.1038/sj.mp.4001003)
• Coleman, S. L., Buckland, P. R., Hoogendoorn, B., Guy, C., Smith, S. K. and O'Donovan, M. C. 2002. Experimental analysis of the annotation of promoters in the public database. Human Molecular Genetics 11(16), pp. 1817-1821. (10.1093/hmg/11.16.1817)
• Williams, N. M. et al. 2002. Mutation screening and LD mapping in the VCFS deleted region of chromosome 22q11 in schizophrenia using a novel DNA pooling approach. Molecular Psychiatry 7(10), pp. 1092-1100. (10.1038/sj.mp.4001188)
• Williams, N. M. et al. 2002. Determination of the genomic structure and mutation screening in schizophrenic individuals for five subunits of the N-methyl-D-aspartate glutamate receptor. Molecular Psychiatry 7(5), pp. 508-514. (10.1038/sj.mp.4001030)
• Williams, N. M., O'Donovan, M. C. and Owen, M. J. 2002. Genome scans and microarrays: converging on genes for schizophrenia?. Genome Biology 3(4), pp. Reviews1011-Reviews1011.5.
• Zammit, S., O'Donovan, M. C. and Owen, M. J. 2002. Neurogenetics of schizophrenia. In: D'haenen, H., den Boer, J. A. and Willner, P. eds. Biological Psychiatry. Chichester: Wiley, pp. 663-671., (10.1002/0470854871.chxvii9)
• Thapar, A. and O'Donovan, M. C. 2002. Neurogenetics. In: D'haenen, H., den Boer, J. A. and Willner, P. eds. Biological Psychiatry. Chichester: Wiley, pp. 167-180., (10.1002/0470854871.chxii)
• West, A. et al. 2002. Evidence to suggest biased phenotypes in children with Attention Deficit Hyperactivity Disorder from completely ascertained trios. Molecular Psychiatry 7(9), pp. 962-966. (10.1038/sj.mp.4001129)
• Hawi, Z. et al. 2002. Serotonergic system and attention deficit hyperactivity disorder (ADHD): a potential susceptibility locus at the 5-HT(1B) receptor gene in 273 nuclear families from a multi-centre sample. Molecular Psychiatry 7(7), pp. 718-725. (10.1038/sj.mp.4001048)

2001

• Jurewicz, I., Owen, R., O'Donovan, M. C. and Owen, M. J. 2001. Searching for susceptibility genes in schizophrenia. European Neuropsychopharmacology 11(6), pp. 395-398. (10.1016/S0924-977X(01)00116-X)
• Abraham, R. et al. 2001. Substantial linkage disequilibrium across the insulin-degrading enzyme locus but no association with late-onset Alzheimer's disease. Human Genetics 109(6), pp. 646-652. (10.1007/s00439-001-0614-1)
• Kirov, G., Lowry, C. A., Stephens, M., Oldfield, S., O'Donovan, M. C., Lightman, S. L. and Owen, M. J. 2001. Screening ABCG1, the human homologue of the Drosophila white gene, for polymorphisms and association with bipolar affective disorder. Molecular Psychiatry 6(6), pp. 671-677. (10.1038/sj.mp.4000899)
• Williams, H. et al. 2001. Association analysis of TBX1 and schizophrenia. American Journal of Medical Genetics - Neuropsychiatric Genetics 105(7), pp. 561.
• Payton, A. et al. 2001. Examining for association between candidate gene polymorphisms in the dopamine pathway and attention-deficit hyperactivity disorder: a family-based study. Neuroscience Letters 105(5), pp. 464-470. (10.1002/ajmg.1407)
• Bowen, T. et al. 2001. Mutation screening of the KCNN3 gene reveals a rare frameshift mutation [Letter]. Molecular Psychiatry 6(3), pp. 259-260. (10.1038/sj.mp.4000128)
• Jacobsen, N. J. O., Elvidge, G., Franks, E. K. E., O'Donovan, M. C., Craddock, N. J. and Owen, M. J. 2001. CUX2, a potential regulator of NCAM expression: Genomic characterization and analysis as a positional candidate susceptibility gene for bipolar disorder. American Journal of Medical Genetics 105(3), pp. 295-300. (10.1002/ajmg.1325)
• Jacobsen, N. J. O. et al. 2001. Exclusion of the Darier's disease gene, ATP2A2, as a common susceptibility gene for bipolar disorder. Molecular Psychiatry 6(1), pp. 92-97. (10.1038/sj.mp.4000774)
• Williams, N. et al. 2001. Screening of candidate genes related to myelination for mutations associated with schizophrenia. American Journal of Medical Genetics - Neuropsychiatric Genetics 105(7), pp. 589.

2000

• Vincent, J. B. et al. 2000. Long repeat tracts at SCA8 in major psychosis. American Journal of Medical Genetics 96(6), pp. 873-876. (10.1002/1096-8628(20001204)96:6<873::AID-AJMG37>3.0.CO;2-9)
• Bowen, T. et al. 2000. No evidence of association from transmission disequilibrium analysis of the hKCa3 gene in bipolar disorder. Bipolar Disorders 2(4), pp. 328-331. (10.1034/j.1399-5618.2000.020406.x)
• Austin, J. et al. 2000. The high affinity neurotensin receptor gene (NTSR1): comparative sequencing and association studies in schizophrenia. Molecular Psychiatry 5(5), pp. 552-557. (10.1038/sj.mp.4000761)
• Williams, H., Murphy, K., Spurlock, G., O'Donovan, M. and Owen, M. 2000. No association of the -277A variant allele of the UFD1L promoter polymorphism and schizophrenia. American Journal of Medical Genetics - Neuropsychiatric Genetics 96(4), pp. 533-534.
• Bray, N. J. et al. 2000. No evidence for association between a non-synonymous polymorphism in the gene encoding human metabotropic glutamate receptor 7 and schizophrenia. Psychiatric Genetics 10(2), pp. 83-86. (10.1097/00041444-200010020-00005)
• Morris, D. W. et al. 2000. Family-based association mapping provides evidence for a gene for reading disability on chromosome 15q. Human Molecular Genetics 9(5), pp. 843-848. (10.1093/hmg/9.5.843)
• Austin, J. et al. 2000. Association analysis of the proneurotensin gene and bipolar disorder. Psychiatric Genetics 10(1), pp. 51-54. (10.1097/00041444-200010010-00009)
• Austin, J. et al. 2000. Comparative sequencing of the proneurotensin gene and association studies in schizophrenia. Molecular Psychiatry 5(2), pp. 208-212. (10.1038/sj.mp.4000693)
• Bowen, T. et al. 2000. Repeat sizes at CAG/CTG loci CTG18.1, ERDA1 and TGC13-7a in schizophrenia. Psychiatric Genetics 10(1), pp. 33-37. (10.1097/00041444-200010010-00006)
• Owen, M. J., Cardno, A. G. and O'Donovan, M. C. 2000. Psychiatric genetics: back to the future. Molecular Psychiatry 5(1), pp. 22-31. (10.1038/sj.mp.4000702)
• Kirov, G., Stephens, M., Williams, N. M., O'Donovan, M. C. and Owen, M. J. 2000. Automated genotyping of single-nucleotide polymorphisms by extension of fluorescently labelled primers: analysis of individual and pooled DNA samples. Balkan Journal of Medical Genetics 3, pp. 23-28.
• Cardno, A. G., O'Donovan, M. C. and Owen, M. J. 2000. Genetic risk factors for schizophrenia. International Journal of Mental Health 29(3), pp. 13-38.
• Speight, G. et al. 2000. Comparative sequencing and association studies of aromatic L-amino acid decarboxylase in schizophrenia and bipolar disorder. Molecular Psychiatry 5(3), pp. 327-331. (10.1038/sj.mp.4000717)
• Hoogendoorn, B. et al. 2000. Cheap, accurate and rapid allele frequency estimation of single nucleotide polymorphisms by primer extension and DHPLC in DNA pools. Human Genetics 107(5), pp. 488-493. (10.1007/s004390000397)
• Williams, N. et al. 2000. Identification and characterisation of SNPs in candidate genes for schizophrenia. American Journal of Medical Genetics - Neuropsychiatric Genetics 96(4), pp. 462.
• Williams, N. et al. 2000. Linkage disequilibrium mapping and candidate gene screening of the VCFS deleted region for mutations associated with schizophrenia. American Journal of Medical Genetics - Neuropsychiatric Genetics 96(4), pp. 475.

1999

• O'Donovan, M. C. and Owen, M. J. 1999. Candidate-gene association studies of schizophrenia. American Journal of Human Genetics 65(3), pp. 587-592. (10.1086/302560)
• Jacobsen, N. J. et al. 1999. ATP2A2 mutations in Darier's disease and their relationship to neuropsychiatric phenotypes. Human Molecular Genetics 8(9), pp. 1631-1636. (10.1093/hmg/8.9.1631)
• Guy, C., Bowen, T., Jones, I. R., McCandless, F., Owen, M. J., Craddock, N. J. and O'Donovan, M. C. 1999. CTG18.1 and ERDA-1 CAG/CTG repeat size in bipolar disorder. Neurobiology of Disease 6(4), pp. 302-307. (10.1006/nbdi.1999.0249)
• Jones, A. C., Austin, J., Hansen, N., Hoogendoorn, B., Oefner, P. J., Cheadle, J. P. and O'Donovan, M. C. 1999. Optimal temperature selection for mutation detection by denaturing HPLC and comparison to single-stranded conformation polymorphism and heteroduplex analysis. Clinical Chemistry 45(8), pp. 1133-1140.
• Cardno, A. G. et al. 1999. CAG repeat length in the hKCa3 gene and symptom dimensions in schizophrenia. Biological Psychiatry 45(12), pp. 1592-1596. (10.1016/s0006-3223(99)00033-5)
• Sakuntabhai, A. et al. 1999. Mutations in ATP2A2, encoding a Ca2+ pump, cause Darier disease. Nature Genetics 21(3), pp. 271-277.
• Franks, E., Guy, C., Jacobsen, N., Bowen, T., Owen, M. J., O'Donovan, M. C. and Craddock, N. J. 1999. Eleven trinucleotide repeat loci that map to chromosome 12 excluded from involvement in the pathogenesis of bipolar disorder. American Journal of Medical Genetics 88(1), pp. 67-70. (10.1002/(SICI)1096-8628(19990205)88:1<67::AID-AJMG12>3.0.CO;2-#)
• Guy, C. et al. 1999. No association between a polymorphic CAG repeat in the human potassium channel gene hKCa3 and bipolar disorder. American Journal of Medical Genetics 88(1), pp. 57-60. (10.1002/(sici)1096-8628(19990205)88:1%3C57::aid-ajmg10%3E3.0.co;2-6)
• Hoogendoorn, B., Owen, M. J., Oefner, P. J., Williams, N. M., Austin, J. and O'Donovan, M. C. 1999. Genotyping single nucleotide polymorphisms by primer extension and high performance liquid chromatography. Human Genetics 104(1), pp. 89-93. (10.1007/s004390050915)

1998

• Li, T. et al. 1998. Analysis of CAG/CTG repeat size in Chinese subjects with schizophrenia and bipolar affective disorder using the repeat expansion detection method. Biological psychiatry 44(11), pp. 1160-1165. (10.1016/S0006-3223(97)00492-7)
• O'Donovan, M. C. et al. 1998. Blind analysis of denaturing high-performance liquid chromatography as a tool for mutation detection. Genomics 52(1), pp. 44-49. (10.1006/geno.1998.5411)
• Bowen, T. et al. 1998. Further support for an association between a polymorphic CAG repeat in the hKCa3 gene and schizophrenia. Molecular Psychiatry 3(3), pp. 266-269. (10.1038/sj.mp.4000400)
• Oretti, R. G., O'Donovan, M. C., McGuffin, P. and Buckland, P. R. 1998. Tryptophan pyrrolase gene expression in an alcohol preferring and non-preferring mouse strain. Addiction Biology 3(1), pp. 71-77. (10.1080/13556219872362)
• Bowen, T. et al. 1998. Linked polymorphisms upstream of exons 1 and 2 of the human cholecystokinin gene are not associated with schizophrenia or bipolar disorder. Molecular Psychiatry 3(1), pp. 67-71. (10.1038/sj.mp.4000293)
• Cardno, A. G. et al. 1998. Association between functional psychosis and expanded CAG/CTG repeats is not explained by health stratification [comparative study]. Psychiatric Genetics 8(1), pp. 29-32. (10.1097/00041444-199800810-00005)

1997

• Jones, L. et al. 1997. No evidence for expanded polyglutamine sequences in bipolar disorder and schizophrenia. Molecular Psychiatry 2(6), pp. 478-482. (10.1038/sj.mp.4000297)
• Craddock, N. J. et al. 1997. Expanded CAG/CTG repeats in bipolar disorder: no correlation with phenotypic measures of illness severity. Biological psychiatry 42(10), pp. 876-881. (10.1016/s0006-3223(96)00516-1)
• Guy, C. et al. 1997. Exclusion of expansion of 50 CAG/CTG trinucleotide repeats in bipolar disorder. American Journal of Psychiatry 154(8), pp. 1146-1147.
• Speight, G. et al. 1997. Exclusion of CAG/CTG trinucleotide repeat loci which map to chromosome 4 in bipolar disorder and schizophrenia. American Journal of Medical Genetics 74(2), pp. 204-206. (10.1002/(SICI)1096-8628(19970418)74:2<204::AID-AJMG19>3.0.CO;2-M)
• O'Donovan, M. C. and Guy, C. 1997. Bias in the genomic distribution of CAG and CTG trinucleotide repeats. American Journal of Medical Genetics 74(1), pp. 62-64. (10.1002/(SICI)1096-8628(19970221)74:1<62::AID-AJMG14>3.0.CO;2-P)

1996

• Craddock, N. J., O'Donovan, M. C. and Owen, M. J. 1996. Introducing Selfcite 2.0--career enhancing software. BMJ 313(7072), pp. 1659-1660. (10.1136/bmj.313.7072.1659)
• Cardno, A. G. et al. 1996. Expanded CAG/CTG repeats in schizophrenia. A study of clinical correlates. British Journal of Psychiatry 169(6), pp. 766-771. (10.1192/bjp.169.6.766)
• O'Donovan, M. C., Craddock, N. J., Guy, C., McGuffin, P. and Owen, M. J. 1996. Involvement of expanded trinucleotide repeats in common diseases. The Lancet 348(9043), pp. 1739-1740. (10.1016/s0140-6736(05)65870-9)
• O'Donovan, M. C. et al. 1996. Confirmation of association between expanded CAG/CTG repeats and both schizophrenia and bipolar disorder. Psychological Medicine -London- 26(6), pp. 1145-1153. (10.1017/s0033291700035868)
• Bowen, T. et al. 1996. Expansion of 50 CAG/CTG repeats excluded in schizophrenia by application of a highly efficient approach using repeat expansion detection and a PCR screening set. American Journal of Human Genetics 59(4), pp. 912-917.
• O'Donovan, M. C. 1996. Genetics of Mental disorders .1. Theoretical aspects - Mendlewicz,J, Papadimitriou,GN. British Journal of Psychiatry 168(2), pp. 256-256.
• O'Donovan, M. C. and Owen, M. J. 1996. Dynamic mutations and psychiatric genetics. Psychological Medicine 26(1), pp. 1-6. (10.1017/S0033291700033663)

1995

• O'Donovan, M. C. et al. 1995. Expanded CAG repeats in schizophrenia and bipolar disorder [letter]. Nature Genetics 10(4), pp. 380-381. (10.1038/ng0895-380)

1994

• Thapar, A., Gottesman, I. I., Owen, M. J., O'Donovan, M. C. and McGuffin, P. 1994. The genetics of mental retardation. The British Journal of Psychiatry 164(6), pp. 747. (10.1192/bjp.164.6.747)
• Spurlock, G., Buckland, P. R., O'Donovan, M. C. and McGuffin, P. 1994. Lack of effect of antidepressant drugs on the levels of mRNAs encoding serotonergic receptors, synthetic enzymes and 5HT transporter. Neuropharmacology 33(3-4), pp. 433-440. (10.1016/0028-3908(94)90073-6)
• McGuffin, P., Owen, M. J., O'Donovan, M. C., Thapar, A. and Gottesman, I. I. 1994. Seminars in psychiatric genetics. Gaskell, Royal College of Psychiatrists.

1993

• Buckland, P. R., O'Donovan, M. C. and McGuffin, P. 1993. Clozapine and sulpiride up-regulate dopamine D3 receptor mRNA levels. Neuropharmacology 32(9), pp. 901-907. (10.1016/0028-3908(93)90146-T)
• McGuffin, P. and O'Donovan, M. C. 1993. Taking a balanced view on triazolam. British Medical Journal (BMJ) 306(6893), pp. 1690-1691. (10.1136/bmj.306.6893.1690-c)
• O'Donovan, M. C. and McGuffin, P. 1993. Correction: Short acting benzodiazepines. British Medical Journal (BMJ) 306(6886), pp. 1146-1146. (10.1136/bmj.306.6886.1146)
• O'Donovan, M. C. and McGuffin, P. 1993. Short acting benzodiazepines.. British Medical Journal (BMJ) 306(6883), pp. 945-946. (10.1136/bmj.306.6883.945)
• O'Donovan, M. C. 1993. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 72(6), pp. 971-983. (10.1016/0092-8674(93)90585-E)
• Buckland, P. R., O'Donovan, M. C. and McGuffin, P. 1993. Both splicing variants of the dopamine D2 receptor mRNA are up-regulated by antipsychotic drugs. Neuroscience Letters 150(1), pp. 25-28. (10.1016/0304-3940(93)90099-7)

1992

• O'Donovan, M. C., Buckland, P. R., Spurlock, G. and McGuffin, P. 1992. Bi-directional changes in the levels of messenger RNAs encoding γ-aminobutyric acidA receptor α subunits after flurazepam treatment. European Journal of Pharmacology: Molecular Pharmacology 226(4), pp. 335-341. (10.1016/0922-4106(92)90051-V)
• O'Donovan, M. C. and Owen, M. J. 1992. Advances and Retreats in the Molecular Genetics of Major Mental Illness. Annals of Medicine 24(3), pp. 171-177. (10.3109/07853899209147816)
• O'Donovan, M. C., Buckland, P. R. and McGuffin, P. 1992. Levels of GABAa receptor subunit mRNA in rat brain following flurazepam treatment. Journal of Psychopharmacology 6(3), pp. 364-369. (10.1177/026988119200600304)
• Buckland, P. R., O'Donovan, M. C. and McGuffin, P. 1992. Changes in dopamine D1, D2 and D3 receptor mRNA levels in rat brain following antipsychotic treatment. Psychopharmacology 106(4), pp. 479-483. (10.1007/BF02244818)
• Buckland, P. R., O'Donovan, M. C. and McGuffin, P. 1992. Changes in dopa decarboxylase mRNA but not tyrosine hydroxylase mRNA levels in rat brain following antipsychotic treatment. Psychopharmacology 108(1-2), pp. 98-102. (10.1007/BF02245292)
• Buckland, P. R., O'Donovan, M. C. and McGuffin, P. 1992. Lack of effect of chronic antipsychotic treatment on dopamine D5 receptor mRNA level. European Neuropsychopharmacology 2(4), pp. 405-409. (10.1016/0924-977X(92)90002-P)
• O'Donovan, M. C., Buckland, P. R. and McGuffin, P. 1992. The expression of neuroreceptor genes and benzodiazepine tolerance.. Clinical Neuropharmacology 15(Supp1), pp. 218A-219A. (10.1097/00002826-199201001-00114)

1991

• O'Donovan, M. C. and McGuffin, P. 1991. Growing points in psychiatric genetics. British Journal of Hospital Medicine 46(6), pp. 359-360.
• Havard, H. L., Buckland, P. R., O'Donovan, M. C. and McGuffin, P. 1991. The effects of antidepressant drugs on kainate receptor mRNA levels. Neuropharmacology 30(6), pp. 675-677. (10.1016/0028-3908(91)90090-X)
• O'Donovan, M. C. and Buckland, P. R. 1991. Simultaneous quantification of several mRNA species by solution hybridisation with oligonucleotides. Nucleic Acids Research 19(12), pp. 3466. (10.1093/nar/19.12.3466)

1989

• Espie, C., Pashley, A., Bonham, K., Sourindhrin, I. and O'Donovan, M. C. 1989. The mentally handicapped person with epilepsy: a comparative study investigating psychosocial functioning.. Journal of Mental Health Defiency Research 33(2), pp. 123-135.