Studies and trials

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ABACus (Awareness and beliefs about cancer) is a randomised controlled trial of the health check intervention to improve cancer symptom awareness and help-seeking among people living in socioeconomically deprived communities.


AML16 and LI-1 together have evaluated (or are in the process of evaluating) 11 novel therapies with more treatments due to come on board later in 2016.

AML15, AML16

In patients given intensive chemotherapy, AML16 for the first time demonstrated the value of measuring response using sophisticated laboratory techniques to identify patients who, although they might be in remission, will relapse early and are therefore candidates for novel treatments or intensification.


Between 2009 and 2014 AML17 recruited over 3,500 patients aged generally under 60 to what is the largest ever trial in Acute Myeloid Leukaemia run in the UK.


AML18 is an international trial looking to identify the best treatment for the third course of chemotherapy across 100 centres in the UK, Denmark and Australasia and is focused on older patients with acute myeloid leukaemia and high risk myelodysplastic syndrome.


AML19 is the current trial for younger adults with acute myeloid leukaemia (AML) or high risk myelodysplastic syndrome (MDS).


Community led ANti-psychotic Drug REduction for Adults with Learning Disabilities: A Randomised Double-blind Placebo Controlled Trial.


Biomarker-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection trial.


A study to determine whether adding in a bath emollient is helpful in relieving childhood eczema.


Best-Of is a phase III study assessing the "Best-Of" radiotherapy compared to the "Best-Of" surgery (trans-oral surgery (TOS) in patients with T1-T2, N0 oropharyngeal carcinoma.