Relevant Key Words:

Extracellular Matrix Structure, Function and Proteins

Research Expertise relevant to tissue engineering & repair:

Structure, folding and assembly of multidomain proteins, specifically those of the extracellular matrix (collagens, laminins, nidogen, tenascins, matrilins); alpha-helical coiled coils; protein sequence/structure relationship.

Circular Dichroism (CD) spectroscopy: An AVIV CD215 with a 5-cell thermostated cell holder is available. CD spectroscopy can be useful to

a) estimate the secondary structure of proteins

b) determine whether mutations affect the structure, stability or binding interactions

c) determine the thermodynamics of folding of proteins, peptides and DNA

d) determine the kinetics of folding or drug binding.

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If you have reagents that may be of interest to the CITER Membership, e.g. cell lines, microbiological cultures. Please give a representative list below: