Relevant Key Words:

Molecular genetics, Refractive error, Myopia, Sclera, Extracellular matrix, Quantitative genetics, Quantitative trait loci (QTL), Matrix metalloproteinases

Research Expertise relevant to tissue engineering & repair:

My research is aimed at discovering the causes of high myopia (extreme shortsightedness). The sclera provides the eye with its strength and resilience, and is largely responsible for determining the size and shape of the eye. In myopia, the eye elongates more than usual. I am studying the molecular changes that occur in eyes developing myopia, along with an investigation of “susceptibility genes” for high myopia. Matrix metalloproteinases are implicated in the scleral remodelling that occurs during myopia development.

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If you have reagents that may be of interest to the CITER Membership, e.g. cell lines, microbiological cultures. Please give a representative list below: