School of Biosciences
029 2087 5188
029 2087 6749
Relevant Key Words:
Cell Transplantation, Neurodegenerative Disease, Stem Cells, Behavioural Recovery
Research Expertise relevant to tissue engineering & repair:
Experimental and clinical cell transplantation in the brain. Development of animal models of Parkinson’s and Huntington’s disease for assessing cell transplantation repair, with a focus on anatomical reconstruction and behavioural recovery of function. We are interested in providing the research basis for clinical trials of cell transplantation in PD and HD, and co-ordinate the first UK clinical trial of fetal striatal cell transplantation in HD. A large proportion of the experimental work in the lab is (a) developing and refining genetic animal models of human disease (b) developing and refining behavioural assessment protocols for use in animal models that are valid to the pathology and symptoms of human disease (c) identifying alternatives to human fetal cells as a source for clinical transplantation, with a substantial interest in stem cells (incl. neuronal embryonic precursors, ES cells and adult stem cells) and in using viral vectors for gene therapy, and a supplementary interest in xenotransplantation.
If you have reagents that may be of interest to the CITER Membership, e.g. cell lines, microbiological cultures. Please give a representative list below: