Dr Niklaas Buurma - MRSC, FHEA
Telephone:+44 (0)29 208 70301
Fax:+44 (0)29 208 74030
Research Group: Biological and Organic Chemistry
Dr Buurma’s research is aimed at understanding reactions and interactions in aqueous solutions in order to control processes in water and is focused on two main areas.
The first area involves the development of conjugated DNA-binders with interesting optoelectronic properties for molecular diagnostics and therapeutic purposes as well as for use in self-assembled nanobioelectronic systems. Our contributions to this area include the synthesis of news DNA-binding compounds and subsequent studies of their DNA-binding properties as well as the development of data-analysis software for the analysis of isothermal titration calorimetry (ITC) data for complex coupled equilibria.
The second area of interest involves the study of organic reactions in aqueous solutions. We currently focus on studies of micellar medium effects, kinetic and mechanistic studies of surfactant-assisted metal-catalysed as well as nanoparticle-catalysed reactions. In addition, we study pharmaceutically relevant racemisation processes (in collaboration with AstraZeneca).
The ultimate aim of all our projects is to develop and use our ability to control and direct reactions and interactions in aqueous solution, bringing chemistry, (nano)engineering and nature together.
For more information, click on the 'Research' tab above.
CH0001 Fundamental Aspects of Chemistry