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Major BIOSI Papers 2008

Marsh V, Winton DJ, Williams GT, Dubois N, Trumpp A, Sansom OJ, & Clarke AR (2008) Epithelial Pten is dispensable for intestinal homeostasis, but suppresses adenoma development and progression following Apc mutation Nature Genetics 40: 1436-1444

Reed K, Athineos D, Meniel V, Wilkins J, Ridgeway R, Burke Z, Muncan V, Clarke AR and Sansom OJ (2008) B-catenin deficiency (but not Myc deletion) suppresses the immediate phenotypes of Apc loss in the liver. Proc Natl Acad Sci USA 105(48)18919-18923

Hughes SW, Errington A, Lorincz ML, Kekesi KA, Juhasz G, Orban G, Cope DW, Crunelli V (2008) Novel modes of rhythmic burst firing at cognitively-relevant frequencies in thalamocortical neurons Brain Research (1235)12-20

O'Keeffe G, Gutierrez H, Pandolfi PP, Riccardi C, Davies AM (2008) NGF-promoted axon growth and target innervation requires GITRL-GITR signalling. Nature Neuroscience 11:135-142

Vizard TN, O'Keeffe G, Gutierrez H, Kos CH, Riccardi D, Davies AM (2008) Regulation of axonal and dendritic growth by the extracellular calcium-sensing receptor. Nature Neuroscience 11:285-291

Davies, AM (2008) Neurotrophins giveth and they taketh away Nature Neuroscience 11: 627-628

Krojer T, Sawa, J, Schafer, E, Saibil, HR, Ehrmann, M and T Clausen (2008) Structural basis for the regulated protease and chaperone function of DegP Nature 453:885-890

Krojer, T, Pangerl, K, Kurt, J, Sawa, J, Stingl, C, Mechtler, K, Huber, R, Ehrmann, M, and T.,Clausen (2008) The interplay of PDZ and protease domain of DegP ensures efficient elimination of misfolded proteins Proc Natl Acad Sci USA 105:7702-7707

Wright N, Glazewski S, Hardingham N, Phillips K, Pervolaraki E, Fox K (2008) Laminar analysis of the role of GluR1 in experience-dependent and synaptic depression in barrel cortex Nature Neuroscience 11(10):1140-2

Ehninger D, Li W, Fox K, Stryker MP, Silva AJ (2008) Reversing neurodevelopmental disorders in adults Neuron 60(6):950-60

Cho, J, King, JS, Qian, X, Harwood, AJ, Shears SB (2008) Dephosphorylation of 2,3-bisphosphoglycerate by MIPP expands the regulatory capacity of the Rapoport-Luebering glycolytic shunt. Proc Natl Acad Sci USA 105(16):5998-6003

Krojer T, Pangerl K, Kurt J, Sawa J, Stingl C, Mechtler K, Huber R, Ehrmann M, Clausen T (2008) Interplay of PDZ and protease domain of DegP ensures efficient elimination of misfolded proteins Proc Natl Acad Sci USA 105(22): 7702-7

Groll M, Schellenberg B, Bachmann AS, Archer CR, Huber R, Powell TK, Lindow S, Kaiser M, Dudler R (2008) A plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism Nature 452(7188):755-8

Jones BV, Begley M, Hill C, Gahan CG, Marchesi JR (2008) Functional and comparative metagenomic analysis of bile salt hydrolase activity in the human gut microbiome. Proc Natl Acad Sci USA 105(36):13580-5

Hall J, Whalley HC, McKirdy JW, Rom, Aniuk L, McGonigle D, McIntosh AM, Baig BJ, Gountouna VE, Job DE, Donaldson DI, Sprengelmeyer R, Young AW, Johnstone EC, Lawrie SM (2008) Overactivation of fear systems to neutral faces in schizophrenia Biological Psychiatry 64(1):70-3

Lopez-Juez, E, Dillon, E, Magyar, A, Khan, S, Hazeldine, S, de Jager, S, Murray, JAH, Beemster, G, Bogre, L, and Shanahan, H (2008) Distinct light-mediated gene expression and cell cycle programs in the shoot apex and cotyledons. Plant Cell 20:947-68

McLaren JE, Ramji DP, Karen R Reed, Dimitris Athineos, Valerie S Meniel, Julie A Wilkins, Rachel A Ridgway, Zoe D. Burke, Vanesa Muncan, Alan R. Clarke, Owen J. Sansom (2008) B-catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of Apc loss in the liver. Proc Natl Acad Sci USA 105(48) 18919–18923

Vizard T.N, O'Keeffe GW, Gutierrez H, Kos CH, Riccardi D, Davies AM (2008) Regulation of axonal and dendritic growth by the extracellular calcium-sensing receptor Nature Neuroscience 11:285-291

Sengpiel F (2008) Binocular vision: only half a brain needed Current Biology 18(22):R1054-6

Elgar SJ, Han J and Taylor MV (2008) mef2 activity levels differentially regulate gene expression during Drosophila muscle development Proc Natl Acad Sci USA 105:918-923

Ray A, Van der Goes van Naters WM, Carlson JR (2008) A regulatory code for neuron-specific odor receptor expression. PLoS Biology 6 e125