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Dr Neil Rodrigues 


Selected Publications

Rodrigues, NP and Tipping, AJ (2014). The Transcription Factor GATA2 Regulates Quiescence in Haematopoietic Stem and Progenitor Cells. Tumor Dormancy, Quiescence, and Senescence, Volume 2: Aging, Cancer,  and Noncancer Pathologies. 277-288

Guha, P., Morgan, JW., Mostoslavsky, G., Rodrigues, NP.* and Boyd, AS* (2013). Lack of immune response to differentiated cells derived from syngeneic induced pluripotent stem cells. Cell Stem Cell (on-line prior to publication) (*joint senior author)

Boyd AS.*, Rodrigues, NP.*, Liu, KO., Fu, X and Xu, Y (2012). Immune recognition of induced pluripotent stem cells. Stem Cells 30(5), 797-803. (*joint first authorship)

Rodrigues, NP*, Tipping, AJ, Wang, Z and Enver T (2011). GATA-2 mediated regulation of hematopoietic stem and progenitor cells, myelodysplasia and myeloid leukemia. International Journal of Biochemistry and Cell Biology 44(3):457-60 (*corresponding author)

Kranc, KR., Schepers, H.*, Rodrigues, NP.*, Bamforth, S.D., Villadsen, E., Ferry, H., Bouriez-Jones, T., Sigvardsson, M., Bhattacharya, S., Jacobsen, SEW and Enver, T. (2009). Cited2 is an essential regulator of adult hematopoietic stem cells. Cell Stem Cell 5(6), 659-65 (* joint second authorship)

Tipping, AJ., Pina, C., Castor, A., Hong, D., Rodrigues, NP., Lozzari, L., May, GE., Jacobsen, SEW and Enver, T. (2009) High GATA-2 expression inhibits human hematopoietic stem and progenitor function via effects on cell cycle. Blood 113, 2661 – 2672

Rodrigues, NP., Boyd, AS., Fuggaza, C., May, GE, Guo, YP, Tipping, AJ, Scadden, DT., Vyas, P. and Enver, T. (2008) GATA-2 regulates granulocyte-macrophage progenitor cell function. Blood 112(13), 4862 - 4873

Nijnik A,, Woodbine L., Marchetti C., Dawson S., Lambe T., Liu C., Rodrigues NP., Crockford TL., Cabuy E., Vindigni A., Enver T., Bell JI., Slijepcevic P., Goodnow CC., Jeggo PA. and Cornall RJ (2007) DNA repair is limiting for haematopoietic stem cells during ageing. Nature 447(7145), 686-90

Rodrigues, NP., Janzen, V., Forkert, R., Dombkowski, D., Boyd, AS., Orkin, SH., Enver, T., Vyas, P. and Scadden, DT (2005) Haploinsufficiency of GATA-2 perturbs adult hematopoietic stem cell homeostasis. Blood 106(2), 477-484

Craiu, A., Saito, Y., Limon, A., Eppich, HM., Olson, DP., Rodrigues, N., Adams, GB., Dombkowski, D., Richardson, P., Schlossman, R., Choi, PS., Grogins, J., O'Connor, PG., Cohen, K., Attar, EC., Freshman, J., Rich, R., Mangano, JA., Gribben, JG., Anderson, KC. and Scadden DT (2005) Flowing cells through pulsed electric fields efficiently purges stem cell preparations of contaminating myeloma cells while preserving stem cell function. Blood 105(5), 2235-8

Qiu, J., Takagi, Y., Harada, J., Rodrigues, N., Moskowitz, MA., Scadden, DT and Cheng, T (2004) Regenerative response in ischemic brain restricted by p21cip1/waf1. J. Exp. Med 199 (7), 199(7), 937-45

Adams, GB., Chabner, KT., Foxall, RB., Weibrecht, KW., Rodrigues, NP., Dombkowski, D., Fallon, R., Poznansky, MC. and Scadden DT (2003) Heterologous cells cooperate to augment stem cell migration, homing, and engraftment. Blood 101(1), 45-51

Cheng, T., Shen, H., Rodrigues, N., Stier, S. and Scadden, DT (2001) Transforming growth factor-{beta}1 mediates cell-cycle arrest of primitive hematopoietic cells independent of p21Cip1/Waf1 or p27Kip1. Blood 98(13), 3643-3649

Cheng, T., Rodrigues, N., Dombkowski, D., Stier, S. and Scadden, DT (2000). Stem cell repopulating efficiency governed by p27kip1. Nature Medicine 8, 1235-1240

Cheng, T., Rodrigues, N., Shen, H., Yong-guang, Y., Sykes, M. and Scadden, DT (2000). Hematopoietic stem cell quiescence is maintained by p21cip/waf1. Science 287, 1804-1808