Dr Karen Reed
I have worked as a postdoctoral research associate within the group of Prof. Alan Clarke in Cardiff school of Biosciences since Oct 2002. My research utilises a number of clinically relevant, transgenic mouse models of cancer (principally intestinal and liver cancer) with the aim of clarifying or establishing some of the critical molecular events that contribute to the initiation, establishment and progression of cancer.
Prior to moving to Cardiff, I worked within the group of Prof Wolf Reik at the Babraham Institute, Cambridge, under whose supervision I also completed a PhD (awarded in Sept 2000). Here my research focused on understanding the epigenetic regulation of the imprinted locus on mouse distal chromosome 7 (a chromosome region involved in foetal overgrowth and cancer susceptibility) and I characterised the molecular basis of, and consequential imprinted phenotype of, the novel radiation-induced mouse mutation Minute (Mnt).
Preceding this I graduated from the University of Bath with a BSc honours degree in Applied Biology in 1996. During my degree course I completed a year’s research in The Institute of Medical Genetics, Cardiff, where I characterised the inheritance of multiple genetic markers within families of Rett syndrome patients (a childhood neurodevelopmental disorder) and refined the genetic map of this disease.
My objective now is to develop my own research group using the expertise I have obtained from working at Cambridge and Cardiff.