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Dr Lee Parry  -  PhD

Meniel, V., Song F., Phesse, T.J., Jenkins, J.R., Parry, L., Dunwoodie, S., Watson, A., Clarke, A.R.  Cited1 deficiency suppresses intestinal tumorigenesis through de-repression of the Wnt pathway (2013). PLoS Genet. 9(8):e1003638. doi: 10.1371/journal.pgen.1003638.

Parry, L., Young, M., El-Marjou, F., Clarke, A.R.  Evidence for crucial role of Paneth cells in mediating the intestinal response to injury. (2012) Stem Cells 2013 Apr; 31(4):776-85. doi: 10.1002/stem.1326

Jardé, T., Evans, R.J., McQuillan, K.L., Parry, L., Feng, G.J., Alvares, B., Clarke, A.R., Dale, T.C.  In vivo and in vitro models for the therapeutic targeting of Wnt signaling using a Tet-OΔN89β-catenin system (2012) Oncogene, doi: 10.1038/onc.2012.103

Smartt, H.J.M., Greenhough, A., Ordóñez-Morán, P., Talero, E., Cherry, C.A., Wallam, C.A., Parry, L., Kharusi, M.A., Roberts, H.R., Mariadason, J.M., Clarke, A.R., Huelsken, J., Williams, A.C., Paraskeva, C.  β-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells (2011) Gut, 61(9):1306-14

Parry, L., Clarke, A.R.  The roles of the methyl-CpG binding proteins in cancer (2011) Genes and Cancer, 2(6), pp. 618-630

Cole, A.M., Ridgway, R.A., Derkits, S.E., Parry, L., Barker, N., Clevers, H., Clarke, A.R., Sansom, O.J. P21 loss blocks senescence following Apc loss and provokes tumourigenesis in the renal but not the intestinal epithelium (2010) EMBO Molecular Medicine, 2(11), pp. 472-486

Phesse, T.J., Parry, L., Reed, K.R., Ewan, K.B., Dale, T.C., Sansom, O.J., Clarke, A.R.  Deficiency of Mbd2 attenuates Wnt signaling  (2008) Molecular and Cellular Biology, 28(19), pp. 6094-6103

Wilson, C., Idziaszczyk, S., Parry, L., Guy, C., Griffiths, D.F.R., Lazda, E., Bayne, R.A.L., Smith, A.J.H., Sampson, J.R., Cheadle, J.P.  A mouse model of tuberous sclerosis 1 showing background specific early post-natal mortality and metastatic renal cell carcinoma (2005) Human Molecular Genetics, 14(13), pp. 1839-1850

Kirby, D.M., Salemi, R., Sugiana, C., Ohtake, A., Parry, L., Bell, K.M., Kirk, E.P., Boneh, A., Taylor, R.W., Dahl, H.-H.M., Ryan, M.T., Thorburn, D.R.  NDUFS6 mutations are a novel cause of lethal neonatal mitochondrial complex I deficiency (2004) Journal of Clinical Investigation, 114(6), pp. 837-845

Dixon, P.F., Avery, S., Chambers, E., Feist, S., Mandhar, H., Parry, L., Stone, D.M., Strømmen, H.K., Thurlow, J.K., Tsin-yee Lui, C., Way, K.  Four years of monitoring for viral haemorrhagic septicaemia virus in marine waters around the United Kingdom (2003) Diseases of Aquatic Organisms, 54(3), pp. 175-186

Hodges, A.K., Li, S., Maynard, J., Parry, L., Braverman, R., Cheadle, J.P., DeClue, J.E., Sampson, J.R. Pathological mutations in TSC1 and TSC2 disrupt the interaction between hamartin and tuberin (2001) Human Molecular Genetics, 10(25), pp. 2899-2905

Parry, L., Maynard, J.H., Patel, A., Clifford, S.C., Morrissey, C., Maher, E.R., Cheadle, J.P., Sampson, J.R.  Analysis of the TSC1 and TSC2 genes in sporadic renal cell carcinomas (2001) British Journal of Cancer, 85(8), pp. 1226-1230

Parry, L., Maynard, J., Patel, A., Hodges, A., Von Deimling, A., Sampson, J., Cheadle, J.  Molecular analysis of the TSC1 and TSC2 tumour suppressor genes in sporadic glial and glioneuronal tumours (2000) Human Genetics, 107(4), pp. 350-356

Parry, L., Dixon, P.F.  Stability of nine viral haemorrhagic septicaemia virus (VHSV) isolates in seawater (1997) Bulletin of the European Association of Fish Pathologists, 17(1), pp. 31-36

Dixon, P.F., Feist, S., Kehoe, E., Parry, L., Stone, D.M., Way, K.  Isolation of viral haemorrhagic septicaemia virus from Atlantic herring Clupea harengus from the English channel (1997) Diseases of Aquatic Organisms, 30(2), pp. 81-89