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Dr Andrew Morby  -  PhD


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Link to ScopusTM Database

Selected Publications

J. Shi, W.P. Lindsay, J.W. Huckle, A.P. Morby and N.J. Robinson. Cyanobacterial metallothionein gene expressed in Escherichia coli : Metal binding properties of the expressed protein. FEBS Letters. 303 159-163 1992

J.W. Huckle, A.P. Morby, J.S. Turner and N.J. Robinson. Isolation and nucleotide sequence determination of a prokaryotic metallothionein gene, smtA, and analysis of transcriptional control by trace metal ions. Molecular Microbiology 7 177-188 1993

J.S.Turner, A.P. Morby, B.A. Whitton, A. Gupta and N.J. Robinson. Construction and characterisation of cyanobacterial mutants lacking a functional metallothionein locus. Journal of Biological Chemistry 286 4494-4498 1993

A.P. Morby, J.S. Turner, J.W. Huckle and N.J. Robinson SmtB is a metal-dependent repressor of the cyanobacterial metallothionein gene smtA: Identification of a Zn inhibited DNA-protein complex21 (4) 921-925 1993.

A. P. Morby, J. Hobman and N. L. Brown The role of cysteine residues in the transport of mercuric ions by the Tn501 MerT and MerP mercury resistance proteins Molecular Microbiology, 17, (1), 25-35 (1995)

N.J. Robinson, P.J. Robinson, A. Gupta, A.J. Bleasby, B.A. Whitton and A.P. Morby Singular over-representation of HIP1 in DNA from many cyanobacteria. Nucleic Acids Research 23 729-735 (1995)

D.K. Blencowe, S. J. Marshall and A. P. Morby Preliminary characterisation of zntA, a gene which encodes a Zn(II)/Cd(II)-export protein in Escherichia coli. Biotechnology et alia 2 1-6 (1997)

J.R. Snape, N.A. Walkley, A.P. Morby, S. Nicklin and G.F. White Purification, properties and sequence of glycerol trinitrate reductase from Agrobacterium radiobacter. Journal of Bacteriology 179 7796-7802 (1997)

K.R. Brocklehurst, J.L. Hobman, B. Lawley, L. Blank, S.J. Marshall, N.L. Brown and A.P. Morby. ZntR is a Zn(II)-responsive MerR-like transcriptional regulator of zntA in Escherichia coli. Molecular Microbiology 31 893-902 (1999)

J.R. Wilson, C. Leang, A.P. Morby, J.L. Hobman and N.L. Brown. MerF is a mercury transport protein: different structures but a common mechanism for mercuric ion transporters ? FEBS Letters 472 78-82 (2000).

K.R. Brocklehurst and A.P. Morby. Metal-ion tolerance in Escherichia coli: analysis of transcriptional profiles by gene-array technology. Microbiology 146 2277-2282 (2000)

K.R. Brocklehurst, J.L. Hobman, B. Lawley, L. Blank, S.J. Marshall, N.L. Brown and A.P. Morby. ZntR is aZn(II)-responsive MerR-like transcriptional regulator of zntA in Escherichia coli. Molecular Microbiology 31893-902 (1999)

J.R. Wilson, C. Leang, A.P. Morby, J.L. Hobman and N.L. Brown. MerF is a mercury transport protein:different structures but a common mechanism for mercuric ion transporters ? FEBS Letters 472 78-82 (2000).

K.R. Brocklehurst and A.P. Morby. Metal-ion tolerancein Escherichia coli: analysis of transcriptionalprofiles by gene-array technology. Microbiology 146 2277-2282 (2000)

A. Al-Malki, A.P. Morby and J.L. Harwood. Pea choline kinase: purification, properties and isolation of a cDNA. Biochem Soc Trans. 28 721-723 (2000)

S. Khan, K.R. Brocklehurst, G.W. Jones and A.P. Morby. The functional analysis of directed amino-acidalterations in ZntR from Escherichia coli. Biochem Biophys Res Commun. 299 438-445 (2002).

D.K.Blencowe and A.P. Morby Zn(II)-metabolism in Prokaryotes FEMS Review 27 291-311 (2003).

A.P. Morby Co-Editor FEMS Review issue 27 (2003).

K. R. Brocklehurst, S. J. Megit and A. P. Morby. Characterisation of CadR from Pseudomonas aeruginosa: a Cd(II)-responsive MerR homologue Biochem Biophys ResCommun. 304 234-239 (2003).

D.K.Blencowe and A.P. Morby Zn(II)-metabolism in Prokaryotes FEMS Review 27 291-311 (2003).

A.P. Morby Co-Editor FEMS Review issue 27 (2003).

K. R. Brocklehurst, S. J. Megit and A. P. Morby. Characterisation of CadR from Pseudomonas aeruginosa: a Cd(II)-responsive MerR homologue Biochem Biophys Res Commun. 304 234-239 (2003).

S. Gul, R. Brown, E. May, M. Mazzulla, C. Berry, A.P. Morby & D. Powell Staphylococcus aureus DNA ligase: Characterization of its kinetics of catalysis and development of a high throughput screening compatible chemiluminescent hybridisation protection assay. Biochemical Journal 383 551-9 (2004)

Patents

Genetic Biosensors using chemiluminescence. R.C.Brown, A.P. Morby, P. Kille & J. Cryer MLT 2001 GB2355791

Methods of detecting modification of genetic material and monitoring processes thereof. R.C. Brown, C.Berry, I. Weeks & A.P. Morby 2003 WO 03052138