Dr D. Dafydd Jones - PhD
Click here to see all publications
Selected Publications
Della Pia E, Elliot M*, Jones DD* & Macdonald JE (2012). Orientation-Dependent Electron Transport in a Single Redox Protein. ACS Nano In Press. * joint corresponding authors. See perspective on this paper: http://pubs.acs.org/doi/abs/10.1021/nn205016v?ref=tw
Gamble M, Künze G, Dodson E, Wilson KS & Jones DD (2011). Regulation of an intracellular subtilisin protease activity by a short propeptide sequence through an original combined dual mechanism. Proc Natl Acad Sci 108, 3536-41
Della Pia E, Chi Q*, Jones DD*, Macdonald JE, Ulstrup J. & Elliot M (2011) Single-molecule mapping of long-range electron transport for a cytochrome b562 Nano Letters 11, 176-82. * joint corresponding authors.
Edwards WR, Williams AJ, Morris JL, Allemann RK & Jones DD (2010) Regulation of beta-lactamase activity by remote binding of heme: functional coupling of unrelated proteins through domain insertion. Biochemistry 49, 6541-9.
Vévodová J, Gamble M, Künze G, Ariza A, Dodson E, Jones DD* & Wilson KS* (2010). Crystal structure of an intracellular subtilisin reveals novel structural features unique to this subtilisin family. Structure 18, 744-55. * joint corresponding authors.
Stott KM, Yusof AM, Perham RN & Jones DD (2009). A surface loop directs conformational switching of a lipoyl domain between a folded and a novel misfolded structure. Structure 17, 1117-27.
Baldwin AJ, Arpino JAJ, Edwards WR, Tippmann EM, Jones DD (2009). Expanded chemical diversity sampling through whole protein evolution. Molecular Biosystem 5, 764-766.
Baldwin AJ, Busse K, Simm AM, Jones DD (2008). Expanded molecular diversity generation during directed evolution by trinucleotide exchange. Nucleic Acids Res. 36, e77.
Edwards WR, Busse K, Allemann RK, Jones DD (2008). Linking the functions of unrelated proteins using a novel directed evolution domain insertion method. Nucleic Acids Res. 36, e78.
Jones DD & Barker PD (2005). Controlling self-assembly by linking protein folding, DNA binding and the redox chemistry of haem. Angew Chem Int Ed Engl. 44, 6337-6341.
Jones DD, Stott KM, Howard MJ, Perham RN (2000). Restricted motion of the lipoyl-lysine swinging arm in the pyruvate dehydrogenase complex of Escherichia coli. Biochemistry 39, 8448-59.
Patents
Jones, D.D. (Novozymes A/S). Directed evolution technology concerning the creation of hybrid enzymes with altered properties. WO2005010176.
Jones, D.D. (Cardiff University). A directed evolution technology for altering the amino acid sequence of a protein. WO 2006077411.