Dr Rosalind John - PhD
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Recent Publications (Cardiff)
Under review
Tunster SJ, Van de Pette M and John RM. Fetal overgrowth in the Cdkn1c mouse model of Beckwith-Wiedemann syndrome.
Publications 2011
John RM and Lefebvre L (2011) Developmental regulation of somatic imprints. Differentiation. [Epub ahead of print].
Tunster SJ, Van de Pette M and John RM (2011) BACs as basic tools for studying genomic imprinting. Journal of Biomedicine and Biotechnology 283013.
Publications 2010
John RM (2010). Engineering mouse models to investigate the function of imprinting. Briefings in Functional Genomics 9(4):294-303.
Tycko B and John RM (2010). The role of imprinted genes in placental growth: implications for the developmental origins of health and disease. In “The Role of Placentation in Developmental Programming”(Ed. Burton G), Cambridge University Press.
Wood MD, Hiura H, Tunster SJ, Arima T, Shin J-Y, Higgins MJ and John RM (2010).Autonomous silencing of the imprinted Cdkn1c gene in stem cells. Epigenetics 5(3):1-8.
Tunster SJ, Tycko B and John RM (2010) The imprinted Phlda2 gene regulates extraembryonic energy stores. Molecular and Cellular Biology 30(1):295-306
Hiura H, Sugawara A, Ogawa H, John RM, Miyauchi N, Miyanari Y, Horiike T, Li Y, Yaegashi N, Sasaki H, Kono T and Arima T (2010) A tripartite paternally methylated region within the Gpr1-Zdbf2 imprinted domain on mouse chromosome 1 identified by meDIP-on-chip. Nucleic Acids Research 38(15):4929-4945.
Previous selected publications
Kobayashi H, Hiura H, John RM, Sato A, Otsu E, Kobayashi N, Suzuki R, Suzuki F, Hayashi C, Utsunomiya T, Yaegashi N and Arima T (2009) DNA methylation errors at imprinted loci after assisted conception originate in the parental sperm. European Journal of Human Genetics 17(12):1582-91.
Sowpati DT, Thiagarajan D, Sharma S, Sultana H, John RM, Surani A, Mishra RK and Khosla S (2008) An intronic DNA sequence within the mouse Neuronatin gene exhibits biochemical characteristics of an ICR and acts as a transcriptional activator in Drosophila. Mechanisms of Development 125(11-12):963-73.
Andrews S, Wood M, Tunster S, Barton SC, Surani MA and John RM (2007) Cdkn1c (p57Kip2) is the major regulator of embryonic growth within its imprinted domain on mouse distal chromosome 7. BMC Developmental Biology 7(1):53.
Arima T, Yamasaki K, John RM, Kato K, Sakumi K, Nakabeppu Y, Wake N and Kono T (2006) The human HYMAI/PLAGL1 differentially methylated region acts as an imprint control region in mice. Genomics 88(5):650-658.
Azuara V, Perry P, Sauer S, Spivakov M, Jørgensen HF, John RM, Gouti M, Casanova M, Warnes G, Merkenschlager M and Fisher AG (2006) Chromatin signatures of pluripotent cell lines. Nature Cell Biology 8(5):532-8.