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Dr Clare Hughes  -  PhD


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Link to ScopusTM Database

Selected Publications

Wainwright, SD., Bondeson, J., Caterson, B., Hughes, CE. (2013). ADAMTS4_v1 is a splice variant of ADAMTS4 that is expressed as a protein in human synovium and cleaves aggrecan at the interglobular domain. Arthritis Rheum Jul 29. Doi: 10.1002/art.38102. [Epub ahead of print]

Shu, C., Hughes C., Smith, S.M., Smith, M.M., Hayes, A., Caterson, B., Little, C.B., Melrose, J. (2013). The ovine newborn and human foetal intervertebral disc contain perlecan and aggrecan variably substituted with native 7D4 CS sulphation motif: Spatiotemporal immunolocalisation and co-distribution with Notch-1 in the human foetal disc. Glycoconjugate Journal 30(7):717-725

Guan, F., Li, S., Wang, Z-L., Yang, H., Xue, S., Wang, W., Song, D., Zhou, X., Zhou, W., Chen, J-H., Caterson, B., Hughes, C. (2013). Histopathology of chondronecrosis development in knee articular cartilage in a rat model of Kashin-Beck disease using T-2 toxin and selenium deficiency conditions. Rheumatology International 33:1:157-166.

Li, S., Cao, J., Caterson, B., Hughes, C.E. (2012). Proteoglycan metabolism, cell death and Kashin-Beck Disease. Glycoconjugate 29:5:241-248.

Melrose, J., Isaacs, MD., Smith S., Hughes CE., Little CB., Caterson B., Hayes AJ (2012) Chondroitin sulphate and heparin sulphate sulphation motifs and their proteoglycans are involved in articular cartilage formation during human foetal knee joint development. Histochem Cell Biol. Sept 138;3;461-475 DOI:10.1007/s00418-012-0968-6.

Li S, Hayes AJ, Caterson B, Hughes CE. (2012). The effect of beta-xylosides on the chondrogenic differentiation of mesenchymal stem cells. Histochem Cell Biol. Aug 23. [Epub ahead of print] PMID: 22910844

Serpi M, Bibbo R, Rat S, Roberts H, Hughes C, Caterson B, Alcaraz MJ, Gibert AT, Verson CR, McGuigan C. (2012). Novel Phosphoramidate Prodrugs of N-Acetyl-(D)-Glucosamine with Antidegenerative Activity on Bovine and Human Cartilage Explants. J Med Chem. May 24;55(10):4629-39. Epub 2012 May 11. PMID: 22501024

Hayes AJ, Isaacs MD, Hughes C, Caterson B, Ralphs JR. (2011). Collagen fibrillogenesis in the development of the annulus fibrosus of the intervertebral disc. Eur Cell Mater. 2011 Oct 11;22:226-41. PMID: 22048900 [PubMed - indexed for MEDLINE].

Hayes AJ, Hughes CE, Ralphs JR, Caterson B. (2011). Chondroitin sulphate sulphation motif expression in the ontogeny of the intervertebral disc. Eur Cell Mater. Jan 7;21:1-14. PMID: 21213210.

Hurst S, Zainal Z, Caterson B, Hughes CE, Harwood JL.(2010). Dietary fatty acids and arthritis. Prostaglandins Leukot Essent Fatty Acids. 2010 Apr-Jun;82(4-6):315-8. Epub 2010 Mar 1. PMID: 20189789.