Dr Peter Evans
A Founder of Abcellute, a Spin Out Company from the Cardiff School of Biosciences
The company featured in the top 50 (Daily Telegraph December 2009). The list has been compiled "to show the breadth of cutting edge technology emerging from Britain's universities.” www.telegraph.co.uk/.../Tracking-50-top-university-spin-out-companies.html
Griffiths, B.J.N. and Evans, P.J. (2009) Preservation of Cells II. Japanese Patent Number 4243638 published 9th January. 26 pages.
Griffiths, B.J.N. and Evans,P.J. (2008) Preservation of Cells I. Japanese Patent Number 4129396 published 23rd May. 22 pages.
Yamamoto, T., Kobayashi, M., Tomari, T., Griffiths, B.J.N., Watson, A.B., Suzuki, K., Ebihara, T., Evans, P.J., Ishii,N., Tasiro, N. and Tsutsui, N. (2008) Application of a New Hepatocyte Preservation Technology Using a Unique Matrix for In Vitro Toxicology Assays. Society of Toxicology (47th Annual Meeting) Seattle, Washington, USA.
Yamamoto, T., Kobayashi, M., Griffiths, B.J.N., Evans,P.J., Watson,A.B., Suzuki, K., Ebihara, T. and Tsutsui, N. (2007) Application of a New Hepatocyte Preservation Technology Using a Unique Matrix to Assess the Hepatotoxicity of New Drug Candidates. 6th World Congress on Alternatives and Animal Use in the Life Sciences. Tokyo, Japan.
Griffiths B.J.N and Evans P.J. (2007) Liver Cells from the Shelves. National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) Parliamentary Event. Westminster, London.
Saberi, M.R., Vinh, T.K., Yee, S.W., Griffiths, B.J.N., Evans, P.J. & Simons, C. (2006) Potent CYP19 (Aromatase) 1-[(Benzofuran-2-yl)(phenylmethyl)pyridine, -Imidazole and –Triazole Inhibitors: Synthesis and Biological Evaluation. J. Med. Chem. 49, 1016-1022.
Griffiths, B. & Evans, P. (2006) The Preservation of Hepatocytes at Non-Freezing Temperatures. Medicon Valley- Hepatocyte User Group Symposium, Snekkerstein, Denmark.
Griffiths, B.J.N. and Evans, P.J. (2004) Preservation of Cells. European Patent Specification. EP 1 343 369 B1. pp 1-29.
Anderson, K., Parkes, H., Griffiths, B. and Evans, P. (2004) Measurements for Biotechnology (MfB); Increasing Confidence in Cell-Based Technology. HUG Valencia, Spain. eds. Bayliss, M., Castell, J.V., Hawksworth, G., Maurel, P., Rietstap, F. & Woodrooffe, A. p53 Fundacion ALIVE.
Griffiths, B.J.N. & Evans, P.J. (2003) Toxicity Testing of New Chemical Entities. A 25 page confidential report commissioned by the Welsh School of Pharmacy.
Griffiths, B.N.J. & Evans, P.J. (2003) Patent Application PCT/GB01/05668.
Griffiths, B.J.N. & Evans, P.J. (2001) Early Membrane Depressions in Hepatocytes Cultured on Primaria Supports. Cell Biol. Int. 25: 489-494.
Griffiths, B.J.N. & Evans, P.J. (2001) Membrane Dips Over Nuclei Correlate with DNA Synthesis in Spreading Hepatocytes. J. Structural Biol. 134: 67-75.
Ali, A.R. & Evans, P.J. (2001) Utilization of Amino Acids in Growing Kidney Proximal Tubule Cell Cultures. Cell Biol. Int. 25: 451-465.
Griffiths, B.J.N. & Evans, P.J. (2000) Ultrastructural Changes in Hypothermically Preserved Hepatocytes. Cryobiology 40: 176-181.
Evans, P.J. (1999) Decreased Intracellular Proteolysis Correlates with the Maintenance of Specific Isoenzymes of Cytochrome P450. Cell Biol. Int. 23: 117-124.
Evans, P.J. (1995) Maintenance of Cytochrome P450 Levels in Hepatocytes Preserved on Gelatin Gels. Cell Biol. Int. 19: 855-860.
Evans, P.J. (1994) Protein Degradation in Kidney Proximal Tubule Cell Monolayers. Biochim. Biophys. Acta 1221: 243-249.
Evans, P.J. (1994) Hypothermic Preservation of Hepatocytes on Gelatin Gels. Cell Biol. Int. 18: 999-1008.
Evans, P.J. (1992) Selective Inhibition of the Synthesis of Phosphoenolpyruvate Carboxykinase in Freshly Isolated Proximal Tubule Cells. Biochim. Biophys. Acta 1133: 255-260.
Kumar, S. & Evans, P.J. (1990) Controlled Breakage of Hepatocytes by Sodium Pentobarbitone. Biochem. Pharmacol. (Life Sci. Adv.) 9: 1-4.
Mayne, A.M. & Evans, P.J. (1988) Effect of Antibiotics on the Binding of Pargyline to Monoamine Oxidase in Cultured Hepatocytes. Biochem. Pharmacol. 37: 2823-2832.
Mayne, A.M. & Evans, P.J. (1987) Fate of the Monoamine Oxidase Inhibitor Pargyline in Cultured Hepatocytes. Biochem. Pharmacol. 36: 2289-2295.
Mayer, R.J., Russell, S.M., Amenta, J.S., Evans, P.J., Fernig, D. & Doherty, F. (1985) Intracellular Degradative Fate of Transplanted and Microinjected Proteins. In: Intracellular Protein Catabolism, eds. Khairallah, E.A., Bond, J.S. and Bird, J.W.C. pp 395-404, Alan R. Liss, New York.
Evans, P.J. (1984) Mechanisms of Intracellular Protein Degradation in Primary Cultures of Adult Kidney Cells. Kidney Res. News 23: 3.
Evans, P.J. & Mayer, R.J. (1984) Comparison of the Degradative Fate of Monoamine Oxidase in Endogenous and Transplanted Mitochondrial Outer Membrane in Rat Hepatocytes. Biochem. J. 219, 61-72.
Russell, S.M., Evans, P.J. & Mayer, R.J. (1984) Mitochondrial Transplantation in Hepatocytes and HTC cells:Studies of Subsequent Protein Destruction. Biochem. Soc. Trans. 12: 3
Mayer, R.J., Evans, P.J., Russell, S.M. & Amenta, J.S. (1984) Degradative Fate of Transplanted Proteins. Ciba Found. Symp.103: 202-219.
Brookes, C., Wright, A., Evans, P.J. & Mayer, R.J. (1984) Aflatoxin B1: Effect on the Synthesis and Degradation of Mitochondrial Proteins in Hepatocyte Monolayers. Carcinogenesis 5: 759-765.
Evans,P.J. & Mayer, R. J. (1983) Degradationof Transplanted Mitochondrial Proteins by Hepatocyte Monolayers. Biochem. J. 216: 151-161.
Evans, P.J. (1983) A Non-Enzymic Oxygen Uptake and its Implications in the Assay of 4-Hydroxyphenylpyruvate Dioxygenase by an Oxygen Electrode. Cell. Mol. Life Sci. 39: 274-275.
Evans,P.J.. Russell, S.M., Doherty. F & Mayer, R.J. (1983) Intracellular Protein Degradation: Studies on Transplanted Mitochondrial and Microinjected Cytosolic Proteins. In: Proteinase Inhibitors: Medical and Biological Aspects. Eds. N. Katanuma, H, Holzer & U. Umezawa, pp269-278. Japan Sci. Soc. Press, Tokia/Springer-Verlag, Berlin.
Mayer, R.J., Evans, P.J., Russell, S. M. & Doherty, F. (1982) Fate of Proteins Introduced into Hepatocytes, Hepatomas and Preadipocytes by Organelle Membrane-Cell Fusion or Red Blood Cell Mediated Microinjection. 12th International Congress of Biochemistry. Perth, Australia.
Evans, P.J. & Mayer, R.J. (1982) Organelle-Membrane Cell Fusion; Destruction of Transplanted Mitochondrial Proteins in Hepatocyte Monolayers. Biochem. Biophys. Res. Comm. 107: 51-58.
Evans, P.J. (1982) Purification and Electrophoretic Analysis of Rabbit Cytosolic Tyrosine Aminotransferase. (1982) Enzyme 28: 82-87.
Evans, P.J. (1981) The Regulation of Hepatic Tyrosine Aminotransferase. Biochim. Biophys. Acta 677: 433-444.
Evans, P.J. (1981) A Possible Link Between the Subforms of Tyrosine Aminotransferase and its Inducibility by Dibutyryl cAMP. FEBS Lett. 132: 193-196.