Prof Trevor Dale - PhD
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Selected Publications
Jonker J.W., Freeman, J., Bolscher, E., Alvi, A., Titley, I., Schinkel, A.H., and Trevor C. Dale (2005) Bcrp1 and Mdr1a/1b are required for the side population phenotype in the mammary gland Stem Cells 23 (8) 1059-65
Smalley, M.J., Signoret, N., Ewan, K., Robertson, D., Tilley, Al, Paterson, H. Ding, Y. and Dale, T.C. (2005) Dishevelled (Dvl-2) activates canonical signalling in the absence of cytoplamic puncta. J. Cell Sci. 118 (22) 5279-89
Dale, T. (2005) Protein and nucleic acid together: a mechanism for the emergence of biological selection. J. Theor. Biol. 240 (3) 337-342
Dajani, R. Fraser, E.Roe, S., Yeo, M., Good, V.M., Thompson, V., Dale, T. C., and Pearl, L. H. (2003) Structural basis for recruitment of glycogen synthase kinase 3beta to the axin-APC scaffold complex. EMBO J, 22:494-501.
Fraser, E., Young, N., Dajani, R., Koh, J., Ryves, J. Williams, R., Yeo, M., Webster, M-T., Richardson, C. Smalley, M., Pearl, L. H., Harwood, A. and Dale, T. C. (2002) Identification of Axin and Frat binding region of GSK-3. J. Biol Chem. 277 (3) 2176-85.
Franca-Koh, J., Yeo, M., Fraser, E., Young, N., Dale, T. C. (2002) The regulation of glycogen synthase kinase-3 nuclear export by Frat/GBP. J. Biol. Chem. 277 (46): 43844-8.
Alvi, A. J., Clayton, H., Joshi, C., Enver, T., Ashworth, A., Vivanco, M. d. M., Dale, T. C.*, Smalley, M. J. (2002) Functional and molecular characterisation of mammary SP cells. Breast Cancer Research 5 (1) R1-8.
Dajani, R., Roe, S. M., Sara, E., Young, N., Good, V., Dale, T. C., and Pearl, L.H. (2001) Crystal Structure of Glycogen Synthase Kinase 3b : Structural basis for phosphate-primed substrate specificity. Cell 105 (6) 711-720.
Naylor, S., Smalley, M. J., Robertson, D., Gusterson, B. A., Edwards, P. A. W., and Dale, T. C. (2000). Retroviral expression of Wnt-1 and Wnt-7b produces different effects in mouse mammary epithelium. J. Cell Sci. 113, 2129-2138.
Smalley, M. J., Sara, E., Paterson, H., Naylor, S., Cook, D., Jayatilake, H., Fryer, L., Hutchinson, L., Fry, M. J., Dale, T. C. (1999). Interaction of Axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF-dependent transcription. EMBO J. 18 (10) 2823-2835