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Dr Richard Clarkson  -  PhD

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Link to ScopusTM Database

Selected Publications

Wakefield A, Soukupova J, Montagne A, Ranger J, French R, Muller W and Clarkson R (2012) Bcl3 selectively promotes metastasis of ERBB2-driven mammary tumours Cancer Research (epub) 10.1158/0008-5472.CAN-12-1321

Smalley M, Piggott L and Clarkson R (2012) Breast cancer stem cells: obstacles to therapy.  Cancer Letters (epub)

Piggott L, Omidvar N, Perez S, Eberl M and Clarkson R (2011) Suppression of Apoptosis Inhibitor c-FLIP Selectively Eliminates Breast Cancer Stem Cell Activity in Response to the Anti-cancer Agent, TRAIL.  Breast Cancer Research Sep 14;13(5):R88.

Kreuzaler P., Staniszewska A, Li W, Omidvar N, Kadjouar B, Turkson J, Poli V, Flavell R, Clarkson R, and Watson C (2011) Stat3 controls lysosomal mediated cell death in vivo.  Nature Cell Biology 13 p303-309

Tiffen P, Omidvar N, Marquez, N, Croston D, Watson C, Clarkson R (2008)  A dual role for Oncostatin M signalling in the differentiation and death of mammary epithelial cells in vivo. Mol. Endocrinol. 22 p2677-88

Clarkson R, et al (2006)  The genes induced by STAT3 and STAT5 in mammary epithelial cells define the roles of these STATs in mammary development. Mol. Endocrinol. 20 p675-85

Abell K, Bilancio A, Clarkson RW, et al (2005) Stat3-induced apoptosis requires a molecular switch in PI(3)K subunit composition. Nat Cell Biol. 2005 Apr;7(4):392-8

Clarkson RWE, Wayland M, Lee J, Freeman T and Watson CJ (2003) Gene expression profiling mammary gland development reveals putative roles for death receptors and immune mediators in post-lactational regression Breast Cancer Research 6 (2) pp.92-109

Clarkson R and Watson C (2003) Microarray analysis of the Involution Switch. J. Mammary Gland Biology and Neoplasia, 8 p309-319

Kritikou E, Sharkey A, Abell K, Came P, Anderson E, Clarkson R, Watson C(2003) A dual, non-redundant, role for LIF as a regulator of development and STAT3-mediated cell death in mammary gland. Development. 130 p3459-68.

Clarkson R, Heeley J, Chapman R, Ailleut F, Hay R, Wyllie A, Watson C (2000) NF-kB inhibits apoptosis in murine mammary epithelial cells J Biol Chem. 275: pp.12737-12742

Clarkson RWE, Watson CJ (1999) NF-kB and Apoptosis in Mammary Epithelial Cells J.  Mammary Gland Biology and Neoplasia  4 (2) pp.165-175 

Clarkson RWE, Levitt L, Shang C, Howard T, Waters MJ (1999) Ternary Complex Factors Sap1a and Elk1 Mediate Growth Hormone Induced Transcription of Egr-1 in 3T3-F442A Pre-adipocytes Mol Endocrinol, 13 p619-31  

Clarkson RWE,  Chen C-M,  Harrison S, Wells C, Muscat G, Waters MJ  (1995)  Early Responses of Trans-acting Factors to Growth Hormone in Preadipocytes: Differential Regulation of CCAAT Enhancer Binding Protein Beta and C/EBP delta Mol. Endocrinol 9, 108-121