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Dr Riccardo Brambilla 

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Link to ScopusTM Database

Key bibliometric numbers (24 September 2013)

Publications (only peer reviewed papers): 49 (+1 in press + 2 submitted)

Years: 1988-2013 (25 years)


Total number of citations: 2750

Mean citation per publication: 56.1

H index: 26

Selected Peer Reviewed Publications

Nicola Solari, Alessandra Bonito Oliva, Gilberto Fisone and Riccardo Brambilla. Understanding cognitive deficits in Parkinson’s disease: lessons from preclinical animal models. Learn. Mem. (2013). 20: 592-600. doi:10.1101/lm.032029.113

Milica Cerovic, Raffaele d’Isa, Raffaella Tonini and Riccardo Brambilla. Molecular and cellular mechanisms of dopamine-mediated behavioral plasticity in the striatum. Neurobiology of Learning and Memory 105 (2013) 63–80. doi: 10.1016/j.nlm.2013.06.013.

Steven Millership, Natalia Ninkina, Irina Guschina, Jessica Norton, Riccardo Brambilla, Pieter Oort, Sean Adams, Rowena J. Dennis, Peter J. Voshol, Justin J. Rochford and Vladimir L. Buchman. (2012) Increased lipolysis and altered lipid homeostasis protect γ-synuclein–null mutant mice from diet-induced obesity. PNAS Doi: 10.1073/pnas.1210022110.

Matteo Marti, Donata Rodi, Qin Li, Remo Guerrini, Stefania Fasano, Ilaria Morella, Alessandro Tozzi, Riccardo Brambilla, Paolo Calabresi, Michele Simonato, Erwan Bezard and Michele Morari. (2012) Nociceptin/orphanin FQ receptor agonists attenuate L-DOPA-induced dyskinesias. J Neurosci.  DOI:10.1523/JNEUROSCI.6408-11.2012.

Raffaele d’Isa, Steven Clapcote, Vootele Voikar,  David Wolfer, Karl Peter Giese, Riccardo Brambilla and Stefania Fasano (2011) Mice lacking Ras-GRF1 have impaired fear conditioning but normal spatial memory: convergent evidence from two independent mutant lines. In Special Topic on Cell signaling and behavior (Eds. R. Brambilla and G. Fisone), Front. Behav. Neurosci. DOI: 10.3389/fnbeh.2011.00078 

Silingardi, D., Angelucci, A., De Pasquale, R., Borsotti, M., Squitieri, G., Brambilla, R., Putignano, E., Pizzorusso, T. and Berardi, (2011) N. ERK pathway activation bidirectionally affects visual recognition memory and synaptic plasticity in the perirhinal cortex. In Special Topic on Cell signaling and behavior (Eds. R. Brambilla and G. Fisone), Front. Behav. Neurosci. DOI: 10.3389/fnbeh.2011.00084 

Stefania Fasano and Riccardo Brambilla. (2011) Ras-ERK signaling in behavior: old questions and new perspectives. In Special Topic on Cell Signaling and Behavior (Eds. R. Brambilla and G. Fisone), Front. Behav. Neurosci. DOI: 10.3389/fnbeh.2011.00079 

Fasano, S., Bezard, E., D'Antoni, A., Indrigo, M., Francardo, V., Qin, L., Dovero, S., Cerovic, P., Cenci M.A. and Brambilla R. (2010) Inhibition of Ras-GRF1 in the striatum reverts motor symptoms associated to L-DOPA induced Dyskinesia. PNAS 107, 21824–21829 Doi:10.1073/pnas.1012071107

A. Papale, M. Cerovic and R. Brambilla (2009) Viral Vector Approaches to Modify Gene Expression in the Brain. J. Neurosci. Meth, DOI: 10.1016/j.jneumeth.2009.08.013. Invited Review.

S. Fasano, A. D’Antoni, P. C. Orban, , E. Valjent, E. Putignano, H. Vara, , T. Pizzorusso, M. Giustetto, Y. Bongjune, M. P. Soloway, R. Maldonado, J. Caboche and R. Brambilla. (2009) Ras-Guanine Nucleotide-Releasing Factor 1 (Ras-GRF1) Controls Activation of Extracellular Signal-Regulated Kinase (ERK) Signaling in the Striatum and Long-Term Behavioral Responses to Cocaine. Biol Psychiatry, 66:758 –768 Doi:10.1016/j.biopsych.2009.03.014

C. Cunha, A. Angelucci, A. D’Antoni, M. D. Dobrossy, S. B Dunnett, N.Berardi and R. Brambilla (2009) Brain-Derived Neurotrophic Factor (BDNF) overexpression in the forebrain resultsin learning and memory impairments. Neurobiol Dis. 33(3): 258-268.

M. Marchi, A. D’Antoni, I. Formentini, R. Parra, R. Brambilla, G. M. Ratto and M. Costa (2008) The N-terminal non catalytic domain of ERK1 MAP kinase is responsible for the functional differences with ERK2. PLOS ONE 3(12):e3873. Epub 2008 Dec 4.

Ferguson, S. M., S. Fasano, Yang, P., Brambilla, R., and Robinson, T. E. (2006) Knockout of ERK1 MAPK enhances cocaine-evoked immediate early gene expression and behavioural plasticity. Neuropsychopharmacology 31(12):2660-8.

C. Vantaggiato, I. Formentini, A. Bondanza, C. Bonini, L. Naldini and R. Brambilla (2006) ERK1 and ERK2 mitogen-activated protein kinases affect Ras-dependent cell signaling differentially. J. Biol. 5:14.

Biffi, A. Capotondo, S. Fasano, U. del Carro, S. Marchesini, H. Azuma, M. Malaguti, S. Amadio, R. Brambilla, M. Grompe, C. Bordignon, A. Quattrini and L. Naldini (2006) Gene therapy of metachromatic leukodystrophy reverses neurological damage and deficits in mice. JCI, 116, 3070-3082.

C. Pittenger, S. Fasano, D. Mazzocchi-Jones, S.B. Dunnett, E. R. Kandel and R. Brambilla (2006) Impaired bidirectional synaptic plasticity and procedural memory formation in striatum-specific CREB-deficient mice. J Neurosci. 26, 2808-2813.

Biffi, M. De Palma, A. Quattrini, U. Del Carro, S. Amadio, I. Visigalli, M. Sessa, S. Fasano, R. Brambilla, S. Marchesini, C. Bordignon and L. Naldini. (2004) Correction of Metachromatic Leukodystrophy in the Mouse Model by Transplantation of Genetically Modified Hematopoietic Stem Cells. JCI 113, 1118-1129.

C. Mazzucchelli, C. Vantaggiato, A. Ciamei, S. Fasano, P. Pakhotin, W. Krezel, H. Welzl, D. P. Wolfer, G. Pagès, O. Valverde, A. Marowsky, A. Porrazzo, P.C. Orban, R. Maldonado, M. U. Ehrengruber, V. Cestari, H.-P. Lipp, P. F. Chapman, J. Pouysségur and R. Brambilla (2002) Knockout of ERK1 MAP kinase enhances synaptic plasticity in the striatum and facilitates striatal-mediated learning and memory. Neuron 34, 807-820.

P. C. Orban, P. F. Chapman and R. Brambilla (1999) Is the Ras/MAPK signalling pathway necessary for long-term memory formation? TINS, 22, 38-43.

R. Brambilla, N. Gnesutta, L. Minichiello, G. White, A.J. Roylance, C.E. Herron, M. Ramsay, D.P. Wolfer, V. Cestari, C. Rossi-Arnaud, S.G.N. Grant, P.F. Chapman, H.-P. Lipp, E. Sturani and  R. Klein. (1997) A role for the Ras signaling pathway in synaptic transmission and long-term memory. Nature 390, 281-286.

Books and Book Chapters

Riccardo Brambilla, Editor. Viral Vectors Approaches in Neurobiology and Brain Diseases (Springer-Humana Press). In press (2013). The book contains 17 chapters from different contributors, two of whose authored by Prof. Brambilla.

Fisone G and Brambilla R (2012) Neuronal signaling and behavior. Front. Behav. Neurosci. 6:72. doi:10.3389/fnbeh.2012.00072 (e-Book).

Raffaele d’Isa, Riccardo Brambilla and Stefania Fasano. Behavioral Methods for the Study of Ras-ERK Pathway in Memory Formation and Consolidation: Passive Avoidance and Object Recognition.  In “Ras Signaling ” (L. Trabalzini, Ed.), Methods in Molecular Biology, Humana Press (Springer) (2013), in press.

Daniel Orellana, Ilaria Morella, Marzia Indrigo, Alessandro Papale  and Riccardo Brambilla. The Extracellular Signal-Regulated Kinase (ERK) Cascade in Neuronal Cell Signalling. In “Protein Kinase Technologies” (Mukai, H Ed.), Neuromethods, Springer (2012), Volume 68, Part 2, 133-152. ISBN 978-1-61779-824-5. DOI: 10.1007/978-1-61779-824-5_8.

Raffaele d'Isa, Nicola, Solari, and Riccardo Brambilla. Biological Memory in Animals and in Man. In “Memory Mass Storage” (Campardo G, Tiziani F and Iaculo M Eds.  ), Springer (2011). ISBN 978-3-642-14752-4. Doi:10.1007/978-3-642-14752-4_9

M. Indrigo, A. Papale, D.Orellana and Riccardo Brambilla. Lentiviral vectors to study the differential function of ERK1 and ERK2 MAP kinases. In “MAP Kinase Signaling Protocols” (Seger R, Ed.), Humana Press (Springer) (2010). Methods Mol. Biol., 661, 205-220. ISBN 978-1-60761-795-2. Doi: 10.1007/978-1-60761-795-2_12. *